Spermatocidal Agents
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Spermatocidal Agents
Spermicide is a contraceptive substance that destroys sperm, inserted vaginally prior to intercourse to prevent pregnancy. As a contraceptive, spermicide may be used alone. However, the pregnancy rate experienced by couples using only spermicide is higher than that of couples using other methods. Usually, spermicides are combined with contraceptive barrier methods such as diaphragms, condoms, cervical caps, and sponges. Combined methods are believed to result in lower pregnancy rates than either method alone. Spermicides are typically unscented, clear, unflavored, non-staining, and lubricative. Types and effectiveness The most common active ingredient of spermicides is nonoxynol-9. Spermicides containing nonoxynol-9 are available in many forms, such as jelly (gel), films, and foams. Used alone, spermicides have a perfect use failure rate of 6% per year when used correctly and consistently, and 16% failure rate per year in typical use. Spermicide brands This list of exam ...
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Contraceptive
Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent unwanted pregnancy. Birth control has been used since ancient times, but effective and safe methods of birth control only became available in the 20th century. Planning, making available, and using birth control is called family planning. Some cultures limit or discourage access to birth control because they consider it to be morally, religiously, or politically undesirable. The World Health Organization and Centers for Disease Control and Prevention, United States Centers for Disease Control and Prevention provide guidance on the safety of birth control methods among women with specific medical conditions. The most effective methods of birth control are Sterilization (medicine), sterilization by means of vasectomy in males and tubal ligation in females, intrauterine devices (IUDs), and contraceptive implant, implantable birth control. This is follo ...
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Lactic Acid
Lactic acid is an organic acid. It has a molecular formula . It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as natural sources. Lactic acid is an alpha-hydroxy acid (AHA) due to the presence of a hydroxyl group adjacent to the carboxyl group. It is used as a synthetic intermediate in many organic synthesis industries and in various biochemical industries. The conjugate base of lactic acid is called lactate (or the lactate anion). The name of the derived acyl group is lactoyl. In solution, it can ionize by loss of a proton to produce the lactate ion . Compared to acetic acid, its p''K'' is 1 unit less, meaning lactic acid is ten times more acidic than acetic acid. This higher acidity is the consequence of the intramolecular hydrogen bonding between the α-hydroxyl and the carboxylate group. Lactic acid is chiral, consisting of two enantiomers. One ...
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Snopes
''Snopes'' , formerly known as the ''Urban Legends Reference Pages'', is a Fact checking, fact-checking website. It has been described as a "well-regarded reference for sorting out myths and rumors" on the Internet. The site has also been seen as a source for both validating and Debunker, debunking urban legends and similar stories in Culture of the United States, American popular culture. History 1990s In 1994, David and Barbara Mikkelson created an urban folklore web site that would become ''Snopes.com''. ''Snopes'' was an early online encyclopedia focused on urban legends, which mainly presented search results of user discussions. The site grew to encompass a wide range of subjects and became a resource to which Internet users began submitting pictures and stories of questionable veracity. According to the Mikkelsons, ''Snopes'' predated the search engine concept of fact-checking via search results. David Mikkelson had originally adopted the username "Snopes" (the name o ...
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Macmillan Publishers
Macmillan Publishers (occasionally known as the Macmillan Group; formally Macmillan Publishers Ltd and Macmillan Publishing Group, LLC) is a British publishing company traditionally considered to be one of the 'Big Five' English language publishers. Founded in London in 1843 by Scottish brothers Daniel and Alexander MacMillan, the firm would soon establish itself as a leading publisher in Britain. It published two of the best-known works of Victorian era children’s literature, Lewis Carroll's ''Alice's Adventures in Wonderland'' (1865) and Rudyard Kipling's ''The Jungle Book'' (1894). Former Prime Minister of the United Kingdom, Harold Macmillan, grandson of co-founder Daniel, was chairman of the company from 1964 until his death in December 1986. Since 1999, Macmillan has been a wholly owned subsidiary of Holtzbrinck Publishing Group with offices in 41 countries worldwide and operations in more than thirty others. History Macmillan was founded in London in 1843 by Daniel ...
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Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ...
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Parody
A parody, also known as a spoof, a satire, a send-up, a take-off, a lampoon, a play on (something), or a caricature, is a creative work designed to imitate, comment on, and/or mock its subject by means of satiric or ironic imitation. Often its subject is an original work or some aspect of it (theme/content, author, style, etc), but a parody can also be about a real-life person (e.g. a politician), event, or movement (e.g. the French Revolution or 1960s counterculture). Literary scholar Professor Simon Dentith defines parody as "any cultural practice which provides a relatively polemical allusive imitation of another cultural production or practice". The literary theorist Linda Hutcheon said "parody ... is imitation, not always at the expense of the parodied text." Parody may be found in art or culture, including literature, music, theater, television and film, animation, and gaming. Some parody is practiced in theater. The writer and critic John Gross observes in his ''Oxford Boo ...
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Ig Nobel Prize
The Ig Nobel Prize ( ) is a satiric prize awarded annually since 1991 to celebrate ten unusual or trivial achievements in scientific research. Its aim is to "honor achievements that first make people laugh, and then make them think." The name of the award is a pun on the Nobel Prize, which it parodies, and on the word '' ignoble'' ("not noble"). Organized by the scientific humor magazine, '' Annals of Improbable Research'' (AIR), the Ig Nobel Prizes are presented by Nobel laureates in a ceremony at the Sanders Theater, Harvard University, and are followed by the winners' public lectures at the Massachusetts Institute of Technology. History The Ig Nobels were created in 1991 by Marc Abrahams, editor and co-founder of the '' Annals of Improbable Research'', a former editor-in-chief of the ''Journal of Irreproducible Results'' who has been master of ceremonies at all awards ceremonies. Awards were presented at that time for discoveries "that cannot, or should not, be reproduced ...
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Benzalkonium Chloride
Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound. ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent. ADBACs are a mixture of alkylbenzyldimethylammonium chlorides, in which the alkyl group has various even-numbered alkyl chain lengths. Solubility and physical properties Depending on purity, benzalkonium chloride ranges from colourless to a pale yellow (impure). Benzalkonium chloride is readily soluble in ethanol and acetone. Dissolution in water is ready, upon agitation. Aqueous solutions should be neutral to slightly alkaline. Solutions foam when shaken. Concentrated solutions have a bitter taste and a faint almond-like odour. Standard concentrates are manufactured as 50% and 80% w/w solutions, and sold under trade names such as BC50, BC ...
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Octoxynol-9
Triton X-100 (''n'') is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-( 1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630, which might differ from it mainly in having slightly shorter ethylene oxide chains. As a result, Triton X-100 is slightly more hydrophilic than Igepal CA-630 thus these two detergents may not be considered to be functionally interchangeable for most applications. Triton X-100 was originally a registered trademark of Rohm & Haas Co. It was subsequently purchased by Union Carbide and then acquired by Dow Chemical Company upon the acquisition of Union Carbide. Soon afterward (in 2009), Dow also acquired Rohm & Haas Co. Physical properties Undiluted Triton X-100 is a clear viscous fluid (less viscous than undiluted glycerol). Undiluted Triton X-100 has a viscosity of ab ...
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Nonoxynol-9
Nonoxynol-9, sometimes abbreviated as N-9, is an organic compound that is used as a surfactant. It is a member of the nonoxynol family of nonionic surfactants. N-9 and related compounds are ingredients in various cleaning and cosmetic products. It is widely used in contraceptives for its spermicidal properties. Uses Spermicide As a spermicide, it attacks the acrosomal membranes of the sperm, causing the sperm to be immobilized. Nonoxynol-9 is the active ingredient in most spermicidal creams, jellies, foams, gel, film, and suppositories. Lubricant Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%. Condoms Many models of condoms are lubricated with solutions containing nonoxynol-9. In this role, it has been prom ...
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