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Silicosis
Silicosis is a form of occupational lung disease caused by inhalation of crystalline silica dust. It is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs. It is a type of pneumoconiosis. Silicosis (particularly the acute form) is characterized by shortness of breath, cough, fever, and cyanosis (bluish skin). It may often be misdiagnosed as pulmonary edema (fluid in the lungs), pneumonia, or tuberculosis. Using workplace controls, silicosis is almost always a preventable disease. Silicosis resulted in at least 43,000 deaths globally in 2013, down from at least 50,000 deaths in 1990. The name ''silicosis'' (from the Latin ''silex'', or flint) was originally used in 1870 by Achille Visconti (1836–1911), prosector in the Ospedale Maggiore of Milan. The recognition of respiratory problems from breathing in dust dates to ancient Greeks and Romans. Agricola, in the mid-16th century, wrote about lung problems from dust inhalation i ...
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Abrasive Blasting
Sandblasting, sometimes known as abrasive blasting, is the operation of forcibly propelling a stream of abrasive material against a surface under high pressure to smooth a rough surface, roughen a smooth surface, shape a surface or remove surface contaminants. A pressurised fluid, typically compressed air, or a centrifugal wheel is used to propel the blasting material (often called the ''media''). The first abrasive blasting process was patented by Benjamin Chew Tilghman on 18 October 1870. There are several variants of the process, using various media; some are highly abrasive, whereas others are milder. The most abrasive are shot blasting (with metal shot) and sandblasting (with sand). Moderately abrasive variants include glass bead blasting (with glass beads) and plastic media blasting (PMB) with ground-up plastic stock or walnut shells and corncobs. Some of these substances can cause anaphylactic shock to individuals allergic to the media. A mild version is sodablastin ...
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Occupational Lung Disease
Occupational lung diseases are work-related, lung conditions that have been caused or made worse by the materials a person is exposed to within the workplace. It includes a broad group of diseases, including occupational asthma, industrial bronchitis, chronic obstructive pulmonary disease (COPD), bronchiolitis obliterans, inhalation injury, interstitial lung diseases (such as pneumoconiosis, hypersensitivity pneumonitis, lung fibrosis), infections, lung cancer and mesothelioma. These diseases can be caused directly or due to immunological response to an exposure to a variety of dusts, chemicals, proteins or organisms. Occupational cases of interstitial lung disease may be misdiagnosed as COPD, idiopathic pulmonary fibrosis, or a myriad of other diseases; leading to a delay in identification of the causative agent. Types of occupational lung diseases Asthma Asthma is a respiratory disease that can begin or worsen due to exposure at work and is characterized by episodic narrowing ...
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Pneumonoultramicroscopicsilicovolcanoconiosis
''Pneumonoultramicroscopicsilicovolcanoconiosis'' () is a made up word coined in 1935 by the then president of the National Puzzlers' League, Everett M. Smith. It has sometimes been used as a synonym for the occupational disease known as silicosis, but it should not be as most silicosis is not related to mining of volcanic dusts, and no evidence of silicosis has been found in populations exposed to crystalline silica in volcanic ash. It is the longest word in the English language published in a dictionary, Oxford Dictionaries, which defines it as "an artificial long word said to mean a lung disease caused by inhaling very fine volcanic dust". Clinical and toxicological research conducted on volcanic crystalline silica has found little to no evidence of its ability to cause silicosis/pneumoconiosis-like diseases and geochemical anlayses have shown that there are inherent factors in the crystalline structure which may render volcanic crystalline silica much less pathogenic than some ...
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Pneumoconiosis
Pneumoconiosis is the general term for a class of interstitial lung disease where inhalation of dust ( for example, ash dust, lead particles, pollen grains etc) has caused interstitial fibrosis. The three most common types are asbestosis, silicosis, and coal miner's lung. Pneumoconiosis often causes restrictive impairment, although diagnosable pneumoconiosis can occur without measurable impairment of lung function. Depending on extent and severity, it may cause death within months or years, or it may never produce symptoms. It is usually an occupational lung disease, typically from years of dust exposure during work in mining; textile milling; shipbuilding, ship repairing, and/or shipbreaking; sandblasting; industrial tasks; rock drilling (subways or building pilings); or agriculture. It is one of the most common occupational diseases in the world. Types Depending upon the type of dust, the disease is given different names: * Coalworker's pneumoconiosis (also known as coal miner' ...
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Frances Perkins
Frances Perkins (born Fannie Coralie Perkins; April 10, 1880 – May 14, 1965) was an American workers-rights advocate who served as the 4th United States secretary of labor from 1933 to 1945, the longest serving in that position. A member of the Democratic Party, Perkins was the first woman ever to serve in a presidential cabinet. As a loyal supporter of her longtime friend, President Franklin D. Roosevelt, she helped make labor issues important in the emerging New Deal coalition. She was one of two Roosevelt cabinet members to remain in office for his entire presidency (the other being Interior Secretary Harold L. Ickes). Her most important role came in developing a policy for social security in 1935. She also helped form government policy for working with labor unions, although the union leaders distrusted her. Her Labor Department helped to mediate strikes by way of the United States Conciliation Service. Perkins dealt with many labor questions during World War II, w ...
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Bernardino Ramazzini
Bernardino Ramazzini (; 4 October 1633 – 5 November 1714) was an Italian physician. Ramazzini, along with Francesco Torti, was an early proponent of the use of cinchona bark (from which quinine is derived) in the treatment of malaria. His most important contribution to medicine was his book on occupational diseases, ''De Morbis Artificum Diatriba'' ("Diseases of Workers"). Life Ramazzini was born in Carpi on 4 October 1633 according to his birth certificate. He studied medicine at the University of Parma, where his interest in occupational diseases began. Career He was appointed to the chair of theory of medicine at University of Modena in 1682 then served as professor of medicine at the University of Padua from 1700 until his death. He is often called "the father of occupational medicine" The first edition of ''De Morbis'' was published in 1700 in Modena, the second in 1713 in Padua. Occupational medicine His book on occupational diseases, ''De Morbis Artificum Diatriba ...
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Cor Pulmonale
Pulmonary heart disease, also known as cor pulmonale, is the enlargement and failure of the right ventricle of the heart as a response to increased vascular resistance (such as from pulmonic stenosis) or high blood pressure in the lungs. Chronic pulmonary heart disease usually results in right ventricular hypertrophy (RVH), whereas acute pulmonary heart disease usually results in dilatation. Hypertrophy is an adaptive response to a long-term increase in pressure. Individual muscle cells grow larger (in thickness) and change to drive the increased contractile force required to move the blood against greater resistance. Dilatation is a stretching (in length) of the ventricle in response to acute increased pressure. To be classified as pulmonary heart disease, the cause must originate in the pulmonary circulation system; RVH due to a systemic defect is not classified as pulmonary heart disease. Two causes are vascular changes as a result of tissue damage (e.g. disease, hypoxic in ...
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Pallor
Pallor is a pale color of the skin that can be caused by illness, emotional shock or stress, stimulant use, or anemia, and is the result of a reduced amount of oxyhaemoglobin and may also be visible as pallor of the conjunctivae of the eyes on physical examination. Pallor is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause. It is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar presentations such as hypopigmentation (lack or loss of skin pigment) or simply a fair complexion. Causes * migraine attack or headache * excess estradiol and/or estrone * osteoporosis * emotional response, due to fear, embarrassment, grief, rage * anorexia * anemia, due to blood loss, poor nutrition, or underlying disease such as sickle cell anemia Sickle cell disease (SCD) is a group of blood disorders typicall ...
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Cyanosis
Cyanosis is the change of body tissue color to a bluish-purple hue as a result of having decreased amounts of oxygen bound to the hemoglobin in the red blood cells of the capillary bed. Body tissues that show cyanosis are usually in locations where the skin is thinner, including the mucous membranes, lips, nail beds, and ear lobes. Some medications containing amiodarone or silver, Mongolian spots, large birth marks, and the consumption of food products with blue or purple dyes can also result in the bluish skin tissue discoloration and may be mistaken for cyanosis. Cyanosis is further classified into central cyanosis vs. peripheral cyanosis. Pathophysiology The mechanism behind cyanosis is different depending on whether it is central or peripheral. Central cyanosis Central cyanosis is caused by a decrease in arterial oxygen saturation (SaO2) and begins to show once the concentration of deoxyhemoglobin in the blood reaches a concentration of ≥ 5.0 g/dL (≥ 3.1 mmol/L ...
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Tachypnea
Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing. In adult humans at rest, any respiratory rate of 1220 per minute is considered clinically normal, with tachypnea being any rate above that. Children have significantly higher resting ventilatory rates, which decline rapidly during the first three years of life and then steadily until around 18 years. Tachypnea can be an early indicator of pneumonia and other lung diseases in children, and is often an outcome of a brain injury. Distinction from other breathing terms Different sources produce different classifications for breathing terms. Some of the public describe tachypnea as any rapid breathing. Hyperventilation is then described as increased ventilation of the alveoli (which can occur through increased rate or depth of breathing, or a mix of both) where there is a smaller rise in metabolic carbon dioxide relative to this increase in ventilation. ...
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Fatigue (medical)
Fatigue describes a state of tiredness that does not resolve with rest or sleep. In general usage, fatigue is synonymous with extreme tiredness or exhaustion that normally follows prolonged physical or mental activity. When it does not resolve after rest or sleep, or occurs independently of physical or mental exertion, it may be a symptom of a medical condition that may become severe or progressive. Fatigue can be a feature of a mental disorder such as depression; may be associated with conditions of chronic pain such as fibromyalgia; it may also feature in conditions of chronic low-level inflammation, and be a disease-related symptom in many other conditions. Fatigue often has no known cause, and is recognised as being very complex in nature. Fatigability describes a susceptibility to fatigue. Physical fatigue results from muscle fatigue brought about by intense physical activity. Mental fatigue results from prolonged periods of cognitive activity which impairs cognitive abil ...
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Dyspnea
Shortness of breath (SOB), also medically known as dyspnea (in AmE) or dyspnoea (in BrE), is an uncomfortable feeling of not being able to breathing, breathe well enough. The American Thoracic Society defines it as "a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity", and recommends evaluating dyspnea by assessing the intensity of its distinct sensations, the degree of distress and discomfort involved, and its burden or impact on the patient's activities of daily living. Distinct sensations include effort/work to breathe, chest tightness or pain, and "air hunger" (the feeling of not enough oxygen). The tripod position is often assumed to be a sign. Dyspnea is a normal symptom of heavy physical exertion but becomes disease, pathological if it occurs in unexpected situations, when resting or during light exertion. In 85% of cases it is due to asthma, pneumonia, cardiac ischemia, interstitial lung disease, congesti ...
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