Renal Circulation
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Renal Circulation
The renal circulation supplies the blood to the kidneys via the renal arteries, left and right, which branch directly from the abdominal aorta. Despite their relatively small size, the kidneys receive approximately 20% of the cardiac output. Each renal artery branches into segmental arteries, dividing further into interlobar arteries, which penetrate the renal capsule and extend through the renal columns between the renal pyramids. The interlobar arteries then supply blood to the arcuate arteries that run through the boundary of the cortex and the medulla. Each arcuate artery supplies several interlobular arteries that feed into the afferent arterioles that supply the glomeruli. After filtration occurs, the blood moves through a small network of venules that converge into interlobular veins. As with the arteriole distribution, the veins follow the same pattern: the interlobular provide blood to the arcuate veins then back to the interlobar veins, which come to form the renal v ...
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Renal Pyramid
The renal medulla is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries. The interlobar arteries each in turn branch into arcuate arteries, which in turn branch to form interlobular arteries, and these finally reach the glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum portion of the blood out of the vessel and into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the Loop of Henle, through the distal tubule and finally leaves the kidney by means of the collecting duct, leading to the renal pelvis, the dilated portion of the ureter. The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') contains the structures of th ...
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Kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains on ...
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Renal Vein
The renal veins are large-calibre veins that drain blood filtered by the kidneys into the inferior vena cava. There is one renal vein draining each kidney. Because the inferior vena cava is on the right half of the body, the left renal vein is longer than the right one. Structure One renal vein drains each kidney. A renal vein is situated anterior to its corresponding accompanying renal artery. The renal veins empty into the inferior vena cava, entering it at nearly a 90° angle. Due to the right-ward displacement of the inferior vena cava from the midline, the left renal vein is some 3 times longer than the right one (~7.5 cm and ~2.5 cm, respectively). The renal vein divides into 4 divisions upon entering the kidney: * the anterior branch which receives blood from the anterior portion of the kidney and, * the posterior branch which receives blood from the posterior portion. Tributaries Because the tributaries of the inferior vena cava are not bilaterally symmetrical, the l ...
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Interlobar Veins
The interlobar veins are veins of the renal circulation The renal circulation supplies the blood to the kidneys via the renal arteries, left and right, which branch directly from the abdominal aorta. Despite their relatively small size, the kidneys receive approximately 20% of the cardiac output. Eac ... which drain the renal lobes. External links * - "Renal Vasculature: Efferent Arterioles & Peritubular Capillaries" * - "Urinary System: neonatal kidney, vasculature" Kidney anatomy {{circulatory-stub ...
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Arcuate Veins
The arcuate vein is a vessel of the renal circulation. It is located at the border of the renal cortex and renal medulla The renal medulla is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries whi .... References External links * - "Urinary System: neonatal kidney, vasculature" * - "Urinary System: kidney, PAS stain, arcuate artery and vein, longitudinal" * - "Urinary System: kidney, PAS stain, arcuate artery and vein, transverse" * * - "Renal Vasculature: Major Arteries" * - "Renal Vasculature: Efferent Arterioles & Peritubular Capillaries" Training at wisc-online.com Kidney anatomy {{circulatory-stub ...
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Interlobular Veins
The stellate veins join to form the interlobular veins, which pass inward between the rays Ray may refer to: Fish * Ray (fish), any cartilaginous fish of the superorder Batoidea * Ray (fish fin anatomy), a bony or horny spine on a fin Science and mathematics * Ray (geometry), half of a line proceeding from an initial point * Ray (gra ..., receive branches from the plexuses around the convoluted tubules, and, having arrived at the bases of the renal pyramids, join with the venae rectae. References External links * - "Urinary System: kidney, H&E, interlobular artery and vein" Kidney anatomy {{circulatory-stub ...
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Glomerulus
''Glomerulus'' () is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons. ''Glomerulus'' is the diminutive of the Latin ''glomus'', meaning "ball of yarn". ''Glomerulus'' may refer to: * the filtering unit of the kidney; see Glomerulus (kidney). * a structure in the olfactory bulb; see Glomerulus (olfaction). * the contact between specific cells in the cerebellum; see Glomerulus (cerebellum) The cerebellar glomerulus is a small, intertwined mass of nerve fiber terminals in the granular layer of the cerebellar cortex. It consists of post-synaptic granule cell dendrites and pre-synaptic Golgi cell axon terminals surrounding the pre- .... See also * Glomerulation, a hemorrhage of the bladder {{SIA ...
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Afferent Arteriole
The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems. They play an important role in the regulation of blood pressure as a part of the tubuloglomerular feedback mechanism. The afferent arterioles branch from the renal artery, which supplies blood to the kidneys. The afferent arterioles later diverge into the capillaries of the glomerulus. Regulation When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin–angiotensin–aldosterone system, to increase blood pressure and increase reabsorption of sodium ions into the bloodstream via aldosterone. The macula densa cell can also increase the blood pressure of the afferent arterioles by decreasing the synthesis ...
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Interlobular
Cortical radial arteries, formerly known as interlobular arteries, are renal blood vessels given off at right angles from the side of the arcuate arteries looking toward the cortical substance. The interlobular arteries pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form end-arteries. In their outward course, they give off lateral branches, which are the afferent arterioles that supply the renal corpuscles. The afferent arterioles, then, enter Bowman's capsule and end in the glomerulus. From each glomerulus, the corresponding efferent arteriole arises and then exits the capsule near the point where the afferent arteriole enters. Distally, efferent arterioles branch out to form dense plexuses (i.e., capillary beds) around their adjacent renal tubules. For cortical nephrons, a single network of capillaries, known as the peritubular capillari ...
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Arcuate Arteries
The arcuate arteries of the kidney, also known as arciform arteries, are vessels of the renal circulation. They are located at the border of the renal cortex and renal medulla. They are named after the fact that they are shaped in arcs due to the nature of the shape of the renal medulla. Arcuate arteries arise from renal interlobar arteries The interlobar arteries are vessels of the renal circulation which supply the renal lobes. The interlobar arteries branch from the lobar arteries which branch from the segmental arteries, from the renal artery. They give rise to arcuate arteries .... References External links * - "Urinary System: kidney, PAS stain, arcuate artery and vein, longitudinal" * - "Urinary System: kidney, PAS stain, arcuate artery and vein, transverse" * - "Urinary System: neonatal kidney, vasculature" Kidney anatomy {{circulatory-stub ...
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Interlobar Arteries
The interlobar arteries are vessels of the renal circulation which supply the renal lobes. The interlobar arteries branch from the lobar arteries which branch from the segmental arteries, from the renal artery. They give rise to arcuate arteries The arcuate arteries of the kidney, also known as arciform arteries, are vessels of the renal circulation. They are located at the border of the renal cortex and renal medulla. They are named after the fact that they are shaped in arcs due to the .... References External links * - "Renal Vasculature: Efferent Arterioles & Peritubular Capillaries" * - "Urinary System: neonatal kidney, vasculature" Diagram at eku.edu* * Kidney anatomy {{circulatory-stub ...
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Cardiac Output
In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols Q, \dot Q, or \dot Q_ , edited by Catherine E. Williamson, Phillip Bennett is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by both ventricles of the heart, per unit time (usually measured per minute). Cardiac output (CO) is the product of the heart rate (HR), i.e. the number of heartbeats per minute (bpm), and the stroke volume (SV), which is the volume of blood pumped from the left ventricle per beat; thus giving the formula: :CO = HR \times SV Values for cardiac output are usually denoted as L/min. For a healthy individual weighing 70 kg, the cardiac output at rest averages about 5 L/min; assuming a heart rate of 70 beats/min, the stroke volume would be approximately 70 mL. Because cardiac output is related to the quantity of blood delivered to various parts of the body, it is an important component of how effi ...
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