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Right-handed
In human biology, handedness is an individual's preferential use of one hand, known as the dominant hand, due to it being stronger, faster or more dextrous. The other hand, comparatively often the weaker, less dextrous or simply less subjectively preferred, is called the non-dominant hand. In a study from 1975 on 7688 children in US grades 1-6, Left handers comprised 9.6% of the sample, with 10.5% of male children and 8.7% of female children being left-handed. Handedness is often defined by one's writing hand, as it is fairly common for people to prefer to do some tasks with each hand. There are examples of true ambidexterity (equal preference of either hand), but it is rare—most people prefer using one hand for most purposes. Most of the current research suggests that left-handedness has an epigenetic marker—a combination of genetics, biology and the environment. Because the vast majority of the population is right-handed, many devices are designed for use by right-hand ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambidexterity
Ambidexterity is the ability to use both the right and left hand equally well. When referring to objects, the term indicates that the object is equally suitable for right-handed and left-handed people. When referring to humans, it indicates that a person has no marked preference for the use of the right or left hand. Only about one percent of people are naturally ambidextrous, which equates to about 70,000,000 people in the world. In modern times, it is common to find some people considered ambidextrous who were originally left-handed and who learned to be ambidextrous, either deliberately or as a result of training in schools or in jobs where right-handed habits are often emphasized or required. Since many everyday devices (such as can openers and scissors) are asymmetrical and designed for right-handed people, many left-handers learn to use them right-handedly due to the rarity or lack of left-handed models. Thus, left-handed people are more likely to develop motor skills in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambidexterity
Ambidexterity is the ability to use both the right and left hand equally well. When referring to objects, the term indicates that the object is equally suitable for right-handed and left-handed people. When referring to humans, it indicates that a person has no marked preference for the use of the right or left hand. Only about one percent of people are naturally ambidextrous, which equates to about 70,000,000 people in the world. In modern times, it is common to find some people considered ambidextrous who were originally left-handed and who learned to be ambidextrous, either deliberately or as a result of training in schools or in jobs where right-handed habits are often emphasized or required. Since many everyday devices (such as can openers and scissors) are asymmetrical and designed for right-handed people, many left-handers learn to use them right-handedly due to the rarity or lack of left-handed models. Thus, left-handed people are more likely to develop motor skills in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boxing
Boxing (also known as "Western boxing" or "pugilism") is a combat sport in which two people, usually wearing protective gloves and other protective equipment such as hand wraps and mouthguards, throw punches at each other for a predetermined amount of time in a boxing ring. Although the term "boxing" is commonly attributed to "western boxing", in which only the fists are involved, boxing has developed in various ways in different geographical areas and cultures. In global terms, boxing is a set of combat sports focused on striking, in which two opponents face each other in a fight using at least their fists, and possibly involving other actions such as kicks, elbow strikes, Knee (strike), knee strikes, and headbutts, depending on the rules. Some of the forms of the modern sport are western boxing, Bare-knuckle boxing, bare knuckle boxing, kickboxing, Muay Thai, muay-thai, lethwei, savate, and Sanda (sport), sanda. Boxing techniques have been incorporated into many martial ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Locus (genetics)
In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association mapping, also known as "linkage disequilibrium mapping", is a method of ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University College London
, mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = £1.544 billion (2019/20) , chancellor = Anne, Princess Royal(as Chancellor of the University of London) , provost = Michael Spence , head_label = Chair of the council , head = Victor L. L. Chu , free_label = Visitor , free = Sir Geoffrey Vos , academic_staff = 9,100 (2020/21) , administrative_staff = 5,855 (2020/21) , students = () , undergrad = () , postgrad = () , coordinates = , campus = Urban , city = London, England , affiliations = , colours = Purple and blue celeste , nickname ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Linkage
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more ''linked'' than markers that are far apart. In other words, the nearer two genes are on a chromosome, the lower the chance of recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly ''unlinked'', although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located. Genetic linkage is the most prominent exception to Gregor Mendel's Law of Independent Assortment. The first experiment to demonstrate li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome-wide Association Study
In genomics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of Single-nucleotide polymorphism, genetic variants in different individuals to see if any variant is associated with a trait. GWA studies typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. When applied to human data, GWA studies compare the DNA of participants having varying phenotypes for a particular trait or disease. These participants may be people with a disease (cases) and similar people without the disease (controls), or they may be people with different phenotypes for a particular trait, for example blood pressure. This approach is known as phenotype-first, in which the participants are classified first by their clinical manifestation(s), as oppose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Left-right Asymmetry
Left-right asymmetry, (LR asymmetry) is the process in early embryonic development that Homochirality#Symmetry breaking, breaks the normal symmetry in the Symmetry#In biology, bilateral embryo. In vertebrates, left-right asymmetry is established early in development at a structure called the left-right organizer (the name of which varies between species) and leads to activation of different signalling pathways on the left and right of the embryo. This in turn cause several organs in adults to develop LR asymmetry, such as the tilt of the heart, the different number lung lobes on each side of the body and the position of the stomach and spleen on the right side of the body. If this process does not occur correctly in humans it can result in the syndromes heterotaxy or situs inversus. LR asymmetry is pervasive throughout all animals, including invertebrates. Examples of invertebrate LR asymmetry include the large and small claws of the fiddler crab, asymmetrical gut coiling in ''Dros ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polygenic
A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance. The term "monozygous" is usually used to refer to a hypothetical gene as it is often difficult to distinguish the effect of an individual gene from the effects of other genes and the environment on a particular phenotype. Advances in statistical methodology and high throughput sequencing are, however, allowing researchers to locate candidate genes for the trait. In the case that such a gene is identified, it is referred to as a quantitative trait locus (QTL). These genes are generally pleiotropic as well. The genes that contribute to type 2 diabetes are thought to be mostly polygenes. In July 2016, scientists reported identif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heritability
Heritability is a statistic used in the fields of breeding and genetics that estimates the degree of ''variation'' in a phenotypic trait in a population that is due to genetic variation between individuals in that population. The concept of heritability can be expressed in the form of the following question: "What is the proportion of the variation in a given trait within a population that is ''not'' explained by the environment or random chance?" Other causes of measured variation in a trait are characterized as environmental factors, including observational error. In human studies of heritability these are often apportioned into factors from "shared environment" and "non-shared environment" based on whether they tend to result in persons brought up in the same household being more or less similar to persons who were not. Heritability is estimated by comparing individual phenotypic variation among related individuals in a population, by examining the association between ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silvia Paracchini
Silvia Paracchini FRSE is a geneticist who researches the contribution of genetic variation to neurodevelopmental traits such as dyslexia and human handedness. Education As an undergraduate, Paracchini studied Biological Sciences at the University of Pavia, Italy. During this time she undertook an ERASMUS scholarship project at the Technical University of Denmark. She obtained her DPhil in Human Genetics from the University of Oxford in 2003. Career and research After obtaining her doctorate, Paracchini held a post-doctoral research position with the Wellcome Trust Centre for Human Genetics from 2003 to 2011. In 2011, she was awarded a Royal Society University Research Fellowship. Her research group at the University of St Andrews School of Medicine explores the genetic underpinnings of human behavioral traits like handedness, and neurodevelopment disorders like dyslexia by combining large genetic screenings for quantitative measures followed by gene function characterizatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
