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Prodigiosin
Prodigiosin is the red dyestuff produced by many strains of the bacterium '' Serratia marcescens'', as well as other Gram-negative, gamma proteobacteria such as ''Vibrio psychroerythrus'' and '' Hahella chejuensis''. It is responsible for the pink tint occasionally found in grime that accumulates on porcelain surfaces such as bathtubs, sinks, and toilet bowls. It is in the prodiginines family of compounds which are produced in some Gram-negative gamma proteobacteria, as well as select Gram-positive Actinobacteria (e.g. ''Streptomyces coelicolor''). The name ''prodigiosin'' is derived from '' prodigious'' (''i.e.'' something marvelous). Secondary metabolite Prodigiosin is a secondary metabolite of ''Serratia marcescens''. Because it is easy to detect, it has been used as a model system to study secondary metabolism. Prodigiosin production has long been known to be enhanced by phosphate limitation. In low phosphate conditions, pigmented strains have been shown to grow to a hig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prodiginine Biosynthesis
The prodiginines are a family of red tri pyrrole dyestuffs produced by Gammaproteobacteria (e.g. '' Serratia marcescens'') as well as some Actinomycetota (e.g. ''Streptomyces coelicolor''). The group is named after prodigiosin (prodiginine) and is biosynthesized through a common set of enzymes. They are interesting due to their history and their varied biological activity. Structural types Prodigiosin colour.svg, Prodigiosin Cycloprodigiosin.svg, Cycloprodigiosin Cyclononylprodigiosin.svg, Cyclononylprodigiosin Undecylprodigiosin coloured.svg, Undecylprodigiosin Butyl-meta-cycloheptylprodiginine.svg, Butyl-meta-cycloheptylprodiginine Natural sources The prodiginines are secondary metabolites originally noted in ''Serratia'' species, especially ''Serratia marcescens''. They are also found in Actinomycetes, for example ''Streptomyces coelicolor'' and some marine bacteria, including '' Hahella chejuensis'' and '' Pseudoalteromonas denitrificans''. Cyclononylprodigiosin was is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prodiginines
The prodiginines are a family of red tri pyrrole dyestuffs produced by Gammaproteobacteria (e.g. '' Serratia marcescens'') as well as some Actinomycetota (e.g. ''Streptomyces coelicolor''). The group is named after prodigiosin (prodiginine) and is biosynthesized through a common set of enzymes. They are interesting due to their history and their varied biological activity. Structural types Prodigiosin colour.svg, Prodigiosin Cycloprodigiosin.svg, Cycloprodigiosin Cyclononylprodigiosin.svg, Cyclononylprodigiosin Undecylprodigiosin coloured.svg, Undecylprodigiosin Butyl-meta-cycloheptylprodiginine.svg, Butyl-meta-cycloheptylprodiginine Natural sources The prodiginines are secondary metabolites originally noted in ''Serratia'' species, especially ''Serratia marcescens''. They are also found in Actinomycetes, for example ''Streptomyces coelicolor'' and some marine bacteria, including '' Hahella chejuensis'' and '' Pseudoalteromonas denitrificans''. Cyclononylprodigiosin was is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prodiginine
The prodiginines are a family of red tri pyrrole dyestuffs produced by Gammaproteobacteria (e.g. '' Serratia marcescens'') as well as some Actinomycetota (e.g. ''Streptomyces coelicolor''). The group is named after prodigiosin (prodiginine) and is biosynthesized through a common set of enzymes. They are interesting due to their history and their varied biological activity. Structural types Prodigiosin colour.svg, Prodigiosin Cycloprodigiosin.svg, Cycloprodigiosin Cyclononylprodigiosin.svg, Cyclononylprodigiosin Undecylprodigiosin coloured.svg, Undecylprodigiosin Butyl-meta-cycloheptylprodiginine.svg, Butyl-meta-cycloheptylprodiginine Natural sources The prodiginines are secondary metabolites originally noted in ''Serratia'' species, especially ''Serratia marcescens''. They are also found in Actinomycetes, for example ''Streptomyces coelicolor'' and some marine bacteria, including '' Hahella chejuensis'' and '' Pseudoalteromonas denitrificans''. Cyclononylprodigiosin was is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prodigiosin 1
Prodigiosin is the red dyestuff produced by many strains of the bacterium '' Serratia marcescens'', as well as other Gram-negative, gamma proteobacteria such as ''Vibrio psychroerythrus'' and '' Hahella chejuensis''. It is responsible for the pink tint occasionally found in grime that accumulates on porcelain surfaces such as bathtubs, sinks, and toilet bowls. It is in the prodiginines family of compounds which are produced in some Gram-negative gamma proteobacteria, as well as select Gram-positive Actinobacteria (e.g. ''Streptomyces coelicolor''). The name ''prodigiosin'' is derived from '' prodigious'' (''i.e.'' something marvelous). Secondary metabolite Prodigiosin is a secondary metabolite of ''Serratia marcescens''. Because it is easy to detect, it has been used as a model system to study secondary metabolism. Prodigiosin production has long been known to be enhanced by phosphate limitation. In low phosphate conditions, pigmented strains have been shown to grow to a high ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serratia Marcescens
''Serratia marcescens'' () is a species of rod-shaped, Gram-negative bacteria in the family Yersiniaceae. It is a facultative anaerobe and an opportunistic pathogen in humans. It was discovered in 1819 by Bartolomeo Bizio in Padua, Italy.Serratia marcescens. (2011, April). Retrieved from https://microbewiki.kenyon.edu/index.php/Serratia_marcescens ''S. marcescens'' is commonly involved in hospital-acquired infections (HAIs), also called nosocomial infections, particularly catheter-associated bacteremia, urinary tract infections, and wound infections, and is responsible for 1.4% of HAI cases in the United States. It is commonly found in the respiratory and urinary tracts of hospitalized adults and in the gastrointestinal systems of children. Due to its abundant presence in the environment, and its preference for damp conditions, ''S. marcescens'' is commonly found growing in bathrooms (especially on tile grout, shower corners, toilet water lines, and basins), where it man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces Coelicolor
''Streptomyces albidoflavus'' is a bacterium species from the genus of ''Streptomyces'' which has been isolated from soil from Poland. ''Streptomyces albidoflavus'' produces dibutyl phthalate and streptothricins. Small noncoding RNA Bacterial small RNAs are involved in post-transcriptional regulation. Using deep sequencing ''S. albidoflavus'' transcriptome was analysed at the end of exponential growth. 63 small RNAs were identified. Expression of 11 of them was confirmed by Northern blot. The sRNAs were shown to be only present in ''Streptomyces'' species. sRNA scr4677 (''Streptomyces coelicolor'' sRNA 4677) is located in the intergenic region between anti-sigma factor ''SCO4677'' gene and a putative regulatory protein gene ''SCO4676''. ''scr4677'' expression requires the ''SCO4677'' activity and ''scr4677'' sRNA itself seem to affect the levels of the ''SCO4676''-associated transcripts. Targets of two of ''S. albidoflavus'' noncoding RNAs have been identified. Noncoding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vatican City
Vatican City (), officially the Vatican City State ( it, Stato della Città del Vaticano; la, Status Civitatis Vaticanae),—' * german: Vatikanstadt, cf. '—' (in Austria: ') * pl, Miasto Watykańskie, cf. '—' * pt, Cidade do Vaticano—' * es, Ciudad del Vaticano—' is an independent city-state, microstate and enclave within Rome, Italy. Also known as The Vatican, the state became independent from Italy in 1929 with the Lateran Treaty, and it is a distinct territory under "full ownership, exclusive dominion, and sovereign authority and jurisdiction" of the Holy See, itself a sovereign entity of international law, which maintains the city state's temporal, diplomatic, and spiritual independence. With an area of and a 2019 population of about 453, it is the smallest state in the world both by area and population. As governed by the Holy See, Vatican City State is an ecclesiastical or sacerdotal-monarchical state ruled by the Pope who is the bishop of Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raphael
Raffaello Sanzio da Urbino, better known as Raphael (; or ; March 28 or April 6, 1483April 6, 1520), was an Italian painter and architect of the High Renaissance. His work is admired for its clarity of form, ease of composition, and visual achievement of the Neoplatonic ideal of human grandeur. Together with Leonardo da Vinci and Michelangelo, he forms the traditional trinity of great masters of that period. His father was court painter to the ruler of the small but highly cultured city of Urbino. He died when Raphael was eleven, and Raphael seems to have played a role in managing the family workshop from this point. He trained in the workshop of Perugino, and was described as a fully trained "master" by 1500. He worked in or for several cities in north Italy until in 1508 he moved to Rome at the invitation of the pope, to work on the Vatican Palace. He was given a series of important commissions there and elsewhere in the city, and began to work as an architect. He was s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stationary Phase (biology)
250px, Growth is shown as ''L'' = log(numbers) where numbers is the number of colony forming units per ml, versus ''T'' (time.) Bacterial growth is proliferation of bacterium into two daughter cells, in a process called binary fission. Providing no event occurs, the resulting daughter cells are genetically identical to the original cell. Hence, bacterial growth occurs. Both daughter cells from the division do not necessarily survive. However, if the surviving number exceeds unity on average, the bacterial population undergoes exponential growth. The measurement of an exponential bacterial growth curve in batch culture was traditionally a part of the training of all microbiologists; the basic means requires bacterial enumeration (cell counting) by direct and individual (microscopic, flow cytometry), direct and bulk (biomass), indirect and individual (colony counting), or indirect and bulk (most probable number, turbidity, nutrient uptake) methods. Models reconcile theory with th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Borrelia Burgdorferi
''Borrelia burgdorferi'' is a bacterial species of the spirochete class in the genus '' Borrelia'', and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of ''Borrelia burgdorferi'' sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies. ''B. burgdorferi'' sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. ''Borrelia'' species are Gram-negative. Microbiology ''Borrelia burgdorferi'' is named after the researcher Willy Burgdorfer, who first isolated the bacterium in 1982. ''Borrelia burgdorferi'' is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and survive. Like all other ''Borrelia'' sps., this bacterium is also gram-negative and a spirochete. Borrelia colonies are often smaller, rounded, and white with an elevated center. ''B. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dyestuff
A dye is a colored substance that chemically bonds to the substrate to which it is being applied. This distinguishes dyes from pigments which do not chemically bind to the material they color. Dye is generally applied in an aqueous solution and may require a mordant to improve the fastness of the dye on the fiber. There are two broad categories of dyes: natural and synthetic; Natural dyes are dyes extracted from plants, Insects, or minerals. The majority of natural dyes are vegetable dyes derived from plant sources such as roots, berries, bark, leaves, and wood, as well as other biological sources like fungi. Synthetic dyes are also referred to as "coal tar dyes" because they are derived from substances that, until recently, could only be extracted from coal tar. A synthetic dye consists of a chromophore and an auxochrome added to a benzene derivative. Both dyes and pigments are colored, because they absorb only some wavelengths of visible light. Dyes are usually soluble in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lyme Disease
Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the ''Borrelia'' bacterium, which is spread by ticks in the genus ''Ixodes''. The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. The rash is typically neither itchy nor painful. Approximately 70–80% of infected people develop a rash. Early diagnosis can be difficult. Other early symptoms may include fever, headaches and tiredness. If untreated, symptoms may include loss of the ability to move one or both sides of the face, joint pains, severe headaches with neck stiffness or heart palpitations. Months to years later repeated episodes of joint pain and swelling may occur. Occasionally shooting pains or tingling in the arms and legs may develop. Despite appropriate treatment about 10 to 20% of those affected develop joint pains, memory problems and tiredness for at least six months. Lym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
