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Poly Drug Use
Polysubstance use or poly drug use or refers to the use of combined psychoactive substances. Polysubstance use may be used for entheogenic, recreational, or off-label indications, with both legal and illegal substances. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects, or tolerance, of the primary drug and make the experience more enjoyable with drug synergy effects, or to supplement for primary drug when supply is low. Common combinations The most common psychoactive substances are alcohol, caffeine, cannabis, and nicotine (tobacco, and nicotine replacement therapy). Some of the absolutely most common polysubstance combinations are: * Alcohol combined with cannabis — known as ''cross-fading'' and may easily cause spins in people who are drunk and smoke potent cannabis. * #Ayahuasca, Ayahuasca: N,N-Dimethyltryptamine, DMT combined with MAOIs. * Caffeinated alcoholic drinks Combination drugs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caffeinated Alcoholic Beverage
A caffeinated alcoholic drink is a drink that contains both alcohol (drug), alcohol (also known formally as ethanol) and a significant amount of caffeine. Caffeine, a stimulant, masks some of the depressant effects of alcohol. However, in 2010 and 2011, this type of drink faced criticism for posing health risks to their drinkers. In some places there is a ban on caffeinated alcoholic drinks. Ingredients The main ingredients in caffeinated alcoholic drinks are alcohol (drug), alcohol and caffeine. The caffeine is often added by ingredients like energy drinks, coffee, tea, or dark chocolate, which also can be consumed as side-drinks with any alcoholic drink. Wine column writer Joe Fattorini hypothesize that there's an individual tolerance to bitter flavors and the link between taste in coffee and wine stems from the number of taste buds we have. Caffeine free energy drinks/alcoholic beverages * Guarana – compound of plant-based stimulants ** Cult Shaker – a flavored alcoho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Side Effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug. Developing drugs is a complicated process, because no two people are exactly the same, so even drugs that have virtually no side effects, might be difficult for some people. Also, it is difficult to make a drug that targets one part of the body but that does not affect other parts, the fact that increases the risk of side effects in the untargeted parts. Occasionally, drugs are prescribed or procedures performed specifically for their side effects; in that case, said side effect ceases to be a side effect and is now an intended effect. For instance, X-rays were historically (and are currently) used as an imaging technique; the discovery of their oncolytic capability led to their employ in radiotherapy (ablation o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caffeinated Alcoholic Drink
A caffeinated alcoholic drink is a drink that contains both alcohol (also known formally as ethanol) and a significant amount of caffeine. Caffeine, a stimulant, masks some of the depressant effects of alcohol. However, in 2010 and 2011, this type of drink faced criticism for posing health risks to their drinkers. In some places there is a ban on caffeinated alcoholic drinks. Ingredients The main ingredients in caffeinated alcoholic drinks are alcohol and caffeine. The caffeine is often added by ingredients like energy drinks, coffee, tea, or dark chocolate, which also can be consumed as side-drinks with any alcoholic drink. Wine column writer Joe Fattorini hypothesize that there's an individual tolerance to bitter flavors and the link between taste in coffee and wine stems from the number of taste buds we have. Caffeine free energy drinks/alcoholic beverages * Guarana – compound of plant-based stimulants ** Cult Shaker – a flavored alcohol beverage containing Guarana ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MAOI
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants, especially for treatment-resistant depression and atypical depression. They are also used to treat panic disorder, social anxiety disorder, Parkinson's disease, and several other disorders. Reversible inhibitors of monoamine oxidase A (RIMAs) are a subclass of MAOIs that selectively and reversibly inhibit the MAO-A enzyme. RIMAs are used clinically in the treatment of depression and dysthymia. Due to their reversibility, they are safer in single-drug overdose than the older, irreversible MAOIs, and weaker in increasing the monoamines important in depressive disorder. RIMAs have not gained widespread market share in the United States. Medical uses MAOIs have been found to be effective in the treatment of panic disorder with agoraphobia, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,N-Dimethyltryptamine
''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "business trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
