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Phenylmercury Acetate
Phenylmercuric acetate is an organomercury compound used as a preservative, disinfectant, and antitranspirant. Properties Phenylmercuric acetate forms colorless, lustrous crystals, and is soluble in ethanol, benzene, acetic acid, and sparingly in water. Applications Phenylmercuric acetate has been used as a preservative in eyedrops and paint, disinfectant, former fungicide in agriculture, and a potential fungicide in leather processing. It kills crabgrass, the seedlings of which are especially vulnerable, but leaves most lawn grasses intact. It exhibits anti-fungal activity against a broad range of ocular pathogenic fungi, with the greatest activity against ''Fusarium'' spp, and has been investigated as a potential treatment for keratomycosis. Phenylmercuric acetate was used for disinfecting mucous membranes, but due to toxicological and ecotoxicological reasons, is no longer used. In the 1950s, phenylmercuric acetate was used as a catalyst in 3M Tartan brand polyurethane flexi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organomercury Compound
Organomercury refers to the group of organometallic compounds that contain mercury. Typically the Hg–C bond is stable toward air and moisture but sensitive to light. Important organomercury compounds are the methylmercury(II) cation, CH3Hg+; ethylmercury(II) cation, C2H5Hg+; dimethylmercury, (CH3)2Hg, diethylmercury and merbromin ("Mercurochrome"). Thiomersal is used as a preservative for vaccines and intravenous drugs. The toxicity of organomercury compounds presents both dangers and benefits. Dimethylmercury in particular, is notoriously toxic, but found use as an antifungal agent and insecticide. Merbromin and phenylmercuric borate are used as topical antiseptics, while nitromersol is used as a preservative for vaccines and antitoxins. Synthesis Organomercury compounds are generated by many methods, including the direct reaction of hydrocarbons and mercury(II) salts. In this regard, organomercury chemistry more closely resembles organopalladium chemistry and contrasts wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preservative
A preservative is a substance or a chemical that is added to products such as food products, beverages, pharmaceutical drugs, paints, biological samples, cosmetics, wood, and many other products to prevent decomposition by microbial growth or by undesirable chemical changes. In general, preservation is implemented in two modes, chemical and physical. Chemical preservation entails adding chemical compounds to the product. Physical preservation entails processes such as refrigeration or drying.Erich Lück and Gert-Wolfhard von Rymon Lipinski "Foods, 3. Food Additives" in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2002, Wiley-VCH, Weinheim. Preservative food additives reduce the risk of foodborne infections, decrease microbial spoilage, and preserve fresh attributes and nutritional quality. Some physical techniques for food preservation include dehydration, UV-C radiation, freeze-drying, and refrigeration. Chemical preservation and physical preservation techniques are som ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Disinfectant
A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than sterilization, which is an extreme physical or chemical process that kills all types of life. Disinfectants are generally distinguished from other antimicrobial agents such as antibiotics, which destroy microorganisms within the body, and antiseptics, which destroy microorganisms on living tissue. Disinfectants are also different from biocides—the latter are intended to destroy all forms of life, not just microorganisms. Disinfectants work by destroying the cell wall of microbes or interfering with their metabolism. It is also a form of decontamination, and can be defined as the process whereby physical or chemical methods are used to reduce the amount of pathogenic microorganisms on a surface. Disinfectants can also be used to destroy m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antitranspirant
Antitranspirants are compounds applied to the leaves of plants to reduce transpiration. They are used on Christmas trees, on cut flowers, on newly transplanted shrubs, and in other applications to preserve and protect plants from drying out too quickly. They have also been used to protect leaves from salt burn and fungal diseases . They block the active excretion of hydrogen cation from the guard cells. Due to presence of carbon dioxide, a rapid acidification of cytoplasm takes place leading to stomatal closure. Milbarrow (1974) has described the formation of these chemicals in the chloroplast. It moves to the stomata, where it is responsible for checking the intake of Potassium ion or induces loss of potassium ion from the guard cells. Antitranspirants are of two types: metabolic inhibitors and film-forming antitranspirants. Metabolic inhibitors reduce the stomatal opening and increase the leaf resistance to water vapour diffusion without affecting carbon dioxide uptake. Examp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Antimicrobial Chemotherapy
The ''Journal of Antimicrobial Chemotherapy'' is a peer-reviewed medical journal which covers antimicrobial chemotherapy, including laboratory aspects and clinical use of antimicrobial agents. It is published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy and was established in 1975. In January 2015 J. Peter Donnelly ( Radboud University Nijmegen Medical Centre) became the eighth editor-in-chief replacing Alan P. Johnson (Health Protection Agency, London, United Kingdom). The journal has had two previous publishers. All content is available for free after 12 months while authors also have the option to have their articles published immediately as open access. History The ''Journal of Antimicrobial Chemotherapy'' was founded by David Williams in 1975, who was also its editor for its first six years. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal received a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crabgrass
''Digitaria'' is a genus of plants in the grass family native to tropical and warm temperate regions but can occur in tropical, subtropical, and cooler temperate regions as well. Common names include crabgrass, finger-grass, and fonio. They are slender monocotyledonous annual and perennial lawn, pasture, and forage plants; some are often considered lawn pests. ''Digitus'' is the Latin word for "finger", and they are distinguished by the long, finger-like inflorescences they produce. Uses The seeds are edible, most notably those of fonio (''Digitaria exilis'' and ''Digitaria iburua''), ''Digitaria sanguinalis'', as well as ''Digitaria compacta''. They can be toasted, ground into a flour, made into porridge or fermented to make beer. Fonio has been widely used as a staple crop in parts of Africa. It also has decent nutrient qualities as a forage for cattle. Lawns The prevalent species of ''Digitaria'' in North America are large crabgrass (''D. sanguinalis''), sometimes known a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fungal Keratitis
Fungal keratitis is a fungal infection of the cornea, which can lead to blindness. It generally presents with a red, painful eye and blurred vision. There is also increased sensitivity to light, and excessive tears or discharge. It is caused by fungal organisms such as ''Fusarium'', ''Aspergillus'' or '' Candida''. Fungal keratitis has a worldwide distribution, but is more common in the tropics. Around 1 million people become blind every year due to fungal keratitis. Theodor Leber first described a case of fungal keratitis caused by ''Aspergillus'' in 1879. Signs and symptoms The symptoms of fungal keratitis typically emerge over 5-10 days and present with a painful eye, blurred vision, and redness of eye. There is increased sensitivity to light, and excessive tears or discharge. The symptoms are markedly less as compared to a similar bacterial ulcer. Symptoms may be noted to persist after contact lenses are removed, or following antibiotic treatment. Signs: The eyelids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erythema
Erythema (from the Greek , meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology include nervous blushes. Types * Erythema ab igne * Erythema chronicum migrans * Erythema induratum * Erythema infectiosum (or fifth disease) * Erythema marginatum * Erythema migrans * Erythema multiforme (EM) * Erythema nodosum * Erythema toxicum * Erythema elevatum diutinum * Erythema gyratum repens * Keratolytic winter erythema * Palmar erythema Causes It can be caused by infection, massage, electrical treatment, acne medication, allergies, exercise, solar radiation (sunburn), photosensitization, acute radiation syndrome, mercury toxicity, blister agents, niacin administration, or waxing and tweezing of the hairs—any of which can cause the capillaries to dilate, resulting in redness. Erythema is a common sid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hives
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. Hives may burn or sting. The patches of rash may appear on different body parts, with variable duration from minutes to days, and does not leave any long-lasting skin change. Fewer than 5% of cases last for more than six weeks. The condition frequently recurs. Hives frequently occur following an infection or as a result of an Allergy, allergic reaction such as to medication, insect bites, or food. Psychological stress, cold temperature, or vibration may also be a trigger. In half of cases the idiopathy, cause remains unknown. Risk factors include having conditions such as hay fever or asthma. Diagnosis is typically based on the appearance. Patch testing may be useful to determine the allergy. Prevention is by avoiding whatever it is that causes the condition. Treatment is typically with antihistamines such as diphenhydramine and cetirizine. In severe cases, corticosteroids or leukotriene inhi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) " isotype") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing four Ig-like constant domains (Cε1–Cε4). IgE is thought to be an important part of the immune response against infection by certain parasitic worms, including ''Schistosoma mansoni'', ''Trichinella spiralis'', and ''Fasciola hepatica''. IgE is also utilized during immune defense against certain protozoan parasites such as ''Plasmodium falciparum''. IgE may have evolved as a defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylmercuric Borate
Phenylmercuric borate is a topical antiseptic and disinfectant that is soluble in water, ethanol and glycerol. It was used until the 1990s as an active ingredient in disinfectants and in the field of wound treatment for the skin, mouth and throat, for example under the trade name ''Merfen Orange''. However, it has been replaced by other substances due to the high mercury content. See also * Phenylmercuric nitrate Phenylmercuric nitrate is an organomercury compound with powerful antiseptic and antifungal effects. It was once commonly used as a topical solution for disinfecting wounds, but as with all organomercury compounds it is highly toxic, especially ... References Antiseptics Borates Organomercury compounds Phenyl compounds {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylmercuric Nitrate
Phenylmercuric nitrate is an organomercury compound with powerful antiseptic and antifungal effects. It was once commonly used as a topical solution for disinfecting wounds, but as with all organomercury compounds it is highly toxic, especially to the kidneys, and is no longer used in this application. However it is still used in low concentrations as a preservative in eye drops for ophthalmic use, making it one of the few organomercury derivatives remaining in current medical use. See also * Merbromin * Phenylmercury acetate * Phenylmercuric borate * Thiomersal Thiomersal (INN), or thimerosal (USAN, JAN), is an organomercury compound. It is a well-established antiseptic and antifungal agent. The pharmaceutical corporation Eli Lilly and Company gave thiomersal the trade name Merthiolate. It has been u ... References Antiseptics Organomercury compounds {{chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
