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Perisinusoidal Space
The perisinusoidal space (or space of Disse) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the sinusoids to be absorbed by the hepatocytes. Fenestration and discontinuity of the endothelium facilitates this transport. This space may be obliterated in liver disease, leading to decreased uptake by hepatocytes of nutrients and wastes such as bilirubin. The perisinusoidal space also contains hepatic stellate cells (also known as ''Ito cells''), which store fat or fat soluble vitamins including vitamin A). A variety of insults that cause inflammation can result in the cells transforming into myofibroblasts, resulting in collagen Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanometre
330px, Different lengths as in respect to the molecular scale. The nanometre (international spelling as used by the International Bureau of Weights and Measures; SI symbol: nm) or nanometer (American and British English spelling differences#-re, -er, American spelling) is a units of measurement, unit of length in the International System of Units (SI), equal to one billionth (short scale) of a metre () and to 1000 picometres. One nanometre can be expressed in scientific notation as , and as metres. History The nanometre was formerly known as the millimicrometre – or, more commonly, the millimicron for short – since it is of a micron (micrometre), and was often denoted by the symbol mμ or (more rarely and confusingly, since it logically should refer to a ''millionth'' of a micron) as μμ. Etymology The name combines the SI prefix ''nano-'' (from the Ancient Greek , ', "dwarf") with the parent unit name ''metre'' (from Greek , ', "unit of measurement"). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fat Soluble Vitamins
A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term ''vitamin'' does not include the three other groups of essential nutrients: minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. Some sources list fourteen vitamins, by including choline, but major health organizations list thirteen: vitamin A (as all-''trans''-retinol, all-''trans'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph Disse
Joseph Hugo Vincenz Disse (25 December 1852 – 9 July 1912) was a German anatomist and histologist born in Brakel Brakel () is a municipality in the Belgian province of East Flanders in the Denderstreek and the Flemish Ardennes. The name is derived from a Carolingian villa ''Braglo'' first mentioned in 866 and located in the center of Opbrakel. Since 1970, t ..., North Rhine-Westphalia. Biography Disse studied at the University of Erlangen, and after graduation became an assistant to anatomist Heinrich von Waldeyer-Hartz (1836-1921) at Strassburg. From 1880 to 1888 he was an instructor at the University of Tokyo, and afterwards became an associate professor at the University of Göttingen. From 1895 to 1912 he was a professor at the University of Marburg. He specialized in the fields of microscopic anatomy, embryology and histology. His name is associated with the " space of Disse", which is a perisinosoidal space of the liver. References * University of M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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