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Pelargonic Acid Vanillylamide
Nonivamide, also called pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin. Nonivamide is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the confectionery industry to create a hot sensation, and in the pharmaceutical industry in some formulations as a cheaper alternative to capsaicin. Like capsaicin, it can deter mammals (but not birds or insects) from consuming plants or seeds (e.g. squirrels and bird feeder seeds).http://www.aversiontech.com/hot-and-spicy/nonivamide-pava/Retrieved 16 July 2010 This is consistent with nonivamide's role as a TRPV1 ion channel agonist. Mammalian TRPV1 is activated by heat and capsaicin, but the avian form is insensitive to capsaicin. Nonivamide is used (under the name PAV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methanol
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical and the simplest aliphatic alcohol, with the formula C H3 O H (a methyl group linked to a hydroxyl group, often abbreviated as MeOH). It is a light, volatile, colourless, flammable liquid with a distinctive alcoholic odour similar to that of ethanol (potable alcohol). A polar solvent, methanol acquired the name wood alcohol because it was once produced chiefly by the destructive distillation of wood. Today, methanol is mainly produced industrially by hydrogenation of carbon monoxide. Methanol consists of a methyl group linked to a polar hydroxyl group. With more than 20 million tons produced annually, it is used as a precursor to other commodity chemicals, including formaldehyde, acetic acid, methyl tert-butyl ether, methyl benzoate, anisole, peroxyacids, as well as a host of more specialised chemicals. Occurrence Small amounts of methanol are present in normal, healthy hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FN Herstal
Fabrique Nationale Herstal (), trading as FN Herstal and often referred to as Fabrique Nationale or simply FN, is a leading firearms manufacturer based in Herstal, Belgium. It is currently the largest exporter of military small arms in Europe. FN Herstal is owned by the Herstal Group holding company, which is in turn owned by the regional government of Wallonia. The Herstal Group also owns the Browning Arms Company and the U.S. Repeating Arms Company (Winchester). FN America is the U.S. subsidiary of FN Herstal, which was formed by the merger of FN's previous two American subsidiaries – FN Manufacturing and FNH USA. A United Kingdom based manufacturing facility, FNH UK, is also in operation. Firearms designed and/or manufactured by FN include the Browning Hi-Power and Five-seven pistols, the FAL, FNC, F2000 and SCAR rifles, the P90 submachine gun, the M2 Browning, MAG, Minimi and the FN Evolys machine guns; all have been commercially successful.Miller, David (2001). ''T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lachrymatory Agents
Lachrymatory or lacrymatory may refer to: * Something that has the effect of ''lachrymation'', causing the secretion of tears * Tear gas Tear gas, also known as a lachrymator agent or lachrymator (), sometimes colloquially known as "mace" after the early commercial aerosol, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears. In ad ..., known formally as a ''lachrymatory agent'' or ''lachrymator'' * A lacrymatory, a small vessel of terracotta or glass found in Roman and late Greek tombs, thought to have been used to collect the tears of mourners at funerals {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control Agents
A riot is a form of civil disorder commonly characterized by a group lashing out in a violent public disturbance against authority, property, or people. Riots typically involve destruction of property, public or private. The property targeted varies depending on the riot and the inclinations of those involved. Targets can include shops, cars, restaurants, state-owned institutions, and religious buildings. Riots often occur in reaction to a grievance or out of dissent. Historically, riots have occurred due to poverty, unemployment, poor living conditions, governmental oppression, taxation or conscription, conflicts between ethnic groups (race riot) or religions (sectarian violence, pogrom), the outcome of a sporting event (sports riot, football hooliganism) or frustration with legal channels through which to air grievances. While individuals may attempt to lead or control a riot, riots typically consist of disorganized groups that are frequently "chaotic and exhibit herd beha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylacetylrinvanil
Phenylacetylrinvanil (IDN-5890) is a synthetic analogue of capsaicin which acts as a potent and selective agonist for the TRPV1 receptor, with slightly lower potency than resiniferatoxin, though still around 300 times the potency of capsaicin. It is an amide of vanillylamine and ricinoleic acid, with the hydroxyl group on ricinoleic acid esterified with phenylacetic acid Phenylacetic acid (PAA; conjugate base phenylacetate), also known by various synonyms, is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a strong honey-like odor. Endogen .... It is used to study the function of the TRPV1 receptor and its downstream actions, and has also shown anti-cancer effects ''in vitro''. References Capsaicinoids {{pharm-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PAVA Spray
PAVA spray is an incapacitant spray similar to pepper spray. It is dispensed from a handheld canister, in a liquid stream. It contains a 0.3% solution of pelargonic acid vanillylamide (PAVA), also called nonivamide, a synthetic capsaicinoid (analogue of capsaicin), in a solvent of aqueous ethanol. The propellant is nitrogen. This solution has been selected because this is the minimum concentration which will fulfill the purpose of the equipment; namely to minimise a person's capacity for resistance, without unnecessarily prolonging their discomfort. PAVA is significantly more potent than CS gas. The liquid stream is a spray pattern and has a maximum effective range of up to . Maximum accuracy, however, will be achieved over a distance of . The operating distance is the distance between the canister and the subject's eyes, not the distance between the user and the subject. Effects PAVA primarily affects the eyes, causing closure and severe pain. The pain to the eyes is reported to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blepharospasm
Blepharospasm is any abnormal contraction of the orbicularis oculi muscle. The condition should be distinguished from the more common, and milder, involuntary quivering of an eyelid, known as myokymia, or fasciculation. In most cases, blepharospasm symptoms last for a few days and then disappear without treatment, but in some cases the twitching is chronic and persistent, causing life-long challenges. In these cases, the symptoms are often severe enough to result in functional blindness. The person's eyelids feel like they are clamping shut and will not open without great effort. People have normal eyes, but for periods of time are effectively blind due to their inability to open their eyelids. In contrast, the reflex blepharospasm is due to any pain in and around the eye. It is of two types: essential and reflex blepharospasm. The benign essential blepharospasm (BEB) is a focal dystonia—a neurological movement disorder involving involuntary and sustained contractions of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lacrimation
Tears are a clear liquid secreted by the lacrimal glands (tear gland) found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of tears—basal, reflex, and emotional—vary significantly in composition. The functions of tears include lubricating the eyes (basal tears), removing irritants (reflex tears), and also aiding the immune system. Tears also occur as a part of the body's natural pain response. Emotional secretion of tears may serve a biological function by excreting stress-inducing hormones built up through times of emotional distress. Tears have symbolic significance among humans. Physiology Chemical composition Tears are made up of three layers: lipid, aqueous, and mucous. Tears are composed of water, salts, antibodies, and lysozymes (antibacterial enzymes); though composition varies among different tear types. The composition of tears caused by an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Riot Control
Riot control measures are used by law enforcement, military, paramilitary or security forces to control, disperse, and arrest people who are involved in a riot, unlawful demonstration or unlawful protest. If a riot is spontaneous and irrational, actions which cause people to stop and think for a moment (e.g. loud noises or issuing instructions in a calm tone) can be enough to stop it. However, these methods usually fail when there is severe anger with a legitimate cause, or the riot was planned or organized. Riot control personnel have long used less lethal weapons such as batons and whips to disperse crowds and detain rioters. Since the 1980s, riot control officers have also used tear gas, pepper spray, rubber bullets, stun grenades, and electric tasers. In some cases, riot squads may also use Long Range Acoustic Devices, water cannons, armoured fighting vehicles, aerial surveillance, police dogs or mounted police on horses. Persons performing riot control typically wear p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irritation
Irritation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage. A stimulus or agent which induces the state of irritation is an irritant. Irritants are typically thought of as chemical agents (for example phenol and capsaicin) but mechanical, thermal (heat), and radiative stimuli (for example ultraviolet light or ionising radiations) can also be irritants. Irritation also has non-clinical usages referring to bothersome physical or psychological pain or discomfort. Irritation can also be induced by some allergic response due to exposure of some allergens for example contact dermatitis, irritation of mucosal membranes and pruritus. Mucosal membrane is the most common site of irritation because it contains secretory glands that release mucous which attracts the allergens due to its sticky nature. Chronic irritation is a medical term signifying that afflictive health conditions have been present for a while. There are many dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Weapon
A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action. Munitions or other delivery devices designed to deliver chemical weapons, whether filled or unfilled, are also considered weapons themselves." Chemical weapons are classified as weapons of mass destruction (WMD), though they are distinct from nuclear weapons, biological weapons, and radiological weapons. All may be used in warfare and are known by the military acronym NBC (for nuclear, biological, and chemical warfare). Weapons of mass destruction are distinct from conventional weapons, which are primarily effective due to their explosive, kinetic, or incendiary potential. Chemical weapons can be widely dispe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pepper Spray
Pepper spray, oleoresin capsicum spray, OC spray, capsaicin spray, or capsicum spray is a lachrymatory agent (a compound that irritates the eyes to cause a burning sensation, pain, and temporary blindness) used in policing, riot control, crowd control, and self-defense, including defense against dogs and bears. Its inflammatory effects cause the eyes to close, temporarily taking away vision. This temporary blindness allows officers to more easily restrain subjects and permits people in danger to use pepper spray in self-defense for an opportunity to escape. It also causes temporary discomfort and burning of the lungs which causes shortness of breath. Pepper spray was engineered into a spray originally for defense against bears, mountain lions, wolves and other dangerous predators, and is often referred to colloquially as bear spray. Kamran Loghman, the person who developed it for use in riot control, wrote the guide for police departments on how it should be used. It was s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
