Panicudine
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Panicudine
Panicudine (6-hydroxy-11-deoxy-13-dehydrohetisane) is a C20-diterpene alkaloid of the hetisine type, first isolated from ''Aconitum paniculatum''. It has empirical formula C20H25NO3 and a melting point of 249–250 °C. The structure was determined to be a hetisine type diterpene by noting infrared spectrum absorption bands of 3405 cm−1 (OH), 1718 (C=O), and 1650 (C=C), a proton magnetic resonance spectrum with "secondary hydroxyl, hydroxy (4.02 ppm, m, 1H, W1/2 = 10 Hz), exomethylene (4.87 and 4.76 ppm, br.s, 1H each), and tertiary methyl (1.29 ppm, s, 3H) groups and the absence of ''N''-methyl, ''N''-ethyl group, ethyl, and methoxy groups." Additional ultraviolet spectrum and carbon-13 NMR data, confirmed by high resolution mass spectrometry, completed the determination of the structure. Panicudine was identified as an active antimicrobial substance in the chloroform extract of ''Polygonum aviculare'', a traditional herbal medicine of the Mediterranean coastal regi ...
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Polygonum Aviculare
''Polygonum aviculare'' or common knotgrass is a plant related to buckwheat and dock. It is also called prostrate knotweed, birdweed, pigweed and lowgrass. It is an annual found in fields and wasteland, with white flowers from June to October. It is widespread across many countries in temperate regions, apparently native to Eurasia, naturalized in temperate parts of the Southern Hemisphere. Description Common knotgrass is an annual herb with a semi-erect stem that may grow from high. The leaves are hairless and short-stalked. They are longish-elliptical with short stalks and rounded bases; the upper ones are few and are linear and stalkless. The stipules are fused into a stem-enclosing, translucent sheath known as an ochrea that is membranous and silvery. The flowers are regular, green with white or pink margins. Each has five perianth segments, overlapping at the base, five to eight stamens and three fused carpels. The fruit is a dark brown, three-edged nut. The seeds need l ...
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