Pallidothalamic Tract
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Pallidothalamic Tract
The pallidothalamic tracts (or pallidothalamic connections) are a part of the basal ganglia. They provide connectivity between the internal globus pallidus (GPi) and the thalamus, primarily the ventral anterior nucleus and the ventral lateral nucleus. Anatomy They are composed of the ansa lenticularis, the lenticular fasciculus ( field H2 of Forel), and the thalamic fasciculus ( field H1 of Forel). * The ansa lenticularis is composed of fibers that pass from the ventral aspect of the globus pallidus and sweep around the posterior limb of the internal capsule. They connect with the fibers of the lenticular fasciculus in the field H of Forel to form the thalamic fasciculus. * The lenticular fascicles is composed of fibers that pass from the internal part of the globus pallidus, ''through'' the posterior limb of the internal capsule, around the zona incerta. These fibers connect with the fibers of the ansa lenticularis in the field H of Forel to form the thalamic fasciculus. * The th ...
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Basal Ganglia
The basal ganglia (BG), or basal nuclei, are a group of subcortical nuclei, of varied origin, in the brains of vertebrates. In humans, and some primates, there are some differences, mainly in the division of the globus pallidus into an external and internal region, and in the division of the striatum. The basal ganglia are situated at the base of the forebrain and top of the midbrain. Basal ganglia are strongly interconnected with the cerebral cortex, thalamus, and brainstem, as well as several other brain areas. The basal ganglia are associated with a variety of functions, including control of voluntary motor movements, procedural learning, habit learning, conditional learning, eye movements, cognition, and emotion. The main components of the basal ganglia – as defined functionally – are the striatum, consisting of both the dorsal striatum (caudate nucleus and putamen) and the ventral striatum (nucleus accumbens and olfactory tubercle), the globus pallidus, ...
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Internal Globus Pallidus
The internal globus pallidus (GPi or medial globus pallidus; in rodents its homologue is known as the entopeduncular nucleus) and the external globus pallidus (GPe) make up the globus pallidus. The GPi is one of the output nuclei of the basal ganglia (the other being the substantia nigra pars reticulata). The GABAergic neurons of the GPi send their axons to the ventral anterior nucleus (VA) and the ventral lateral nucleus (VL) in the dorsal thalamus, to the centromedian complex, and to the pedunculopontine complex. The efferent bundle is constituted first of the ansa and lenticular fasciculus, then crosses the internal capsule within and in parallel to the Edinger's comb system then arrives at the laterosuperior corner of the subthalamic nucleus and constitutes the field H2 of Forel, then H, and suddenly changes its direction to form field H1 that goes to the inferior part of the thalamus. The distribution of axonal islands is widespread in the lateral region of the thalamus. Th ...
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Thalamus
The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, allowing hub-like exchanges of information. It has several functions, such as the relaying of sensory signals, including motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalamus is a paired structure of gray matter located in the forebrain which is superior to the midbrain, near the center of the brain, with nerve fibers projecting out to the ...
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Ventral Anterior Nucleus
The ventral anterior nucleus (VA) is a nucleus of the thalamus. It acts with the anterior part of the ventral lateral nucleus to modify signals from the basal ganglia. Inputs and outputs The ventral anterior nucleus receives neuronal inputs from the basal ganglia. Its main afferent fibres are from the globus pallidus. The efferent fibres from this nucleus pass into the premotor cortex The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans. ... for initiation and planning of movement. Functions It helps to function in movement by providing feedback for the outputs of the basal ganglia. Additional images File:Constudthal.gif, Thalamus File:Territoriostalamo.svg, Thalamus References {{DEFAULTSORT:Ventral Anterior Nucleus Thalamus ...
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Ventral Lateral Nucleus
The ventral lateral nucleus (VL) is a nucleus in the ventral nuclear group of the thalamus. Inputs and outputs It receives neuronal inputs from the basal ganglia which includes the substantia nigra and the globus pallidus (via the thalamic fasciculus). It also has inputs from the cerebellum (via the dentatothalamic tract). It sends neuronal output to the primary motor cortex and premotor cortex. The ventral lateral nucleus in the thalamus forms the motor functional division in the thalamic nuclei along with the ventral anterior nucleus. The ventral lateral nucleus receives motor information from the cerebellum and the globus pallidus. Output from the ventral lateral nucleus then goes to the primary motor cortex. Functions The function of the ventral lateral nucleus is to target efferents including the motor cortex, premotor cortex, and supplementary motor cortex. Therefore, its function helps the coordination and planning of movement. It also plays a role in the learning of mov ...
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Ansa Lenticularis
The ansa lenticularis (''ansa lentiformis'' in older texts) is a part of the brain, making up the superior layer of the substantia innominata. Its fibers, derived from the medullary lamina of the lentiform nucleus, pass medially to end in the thalamus and subthalamic region, while others are said to end in the tegmentum and red nucleus. It is classified by NeuroNames as part of the subthalamus The subthalamus or prethalamus is a part of the diencephalon. Its most prominent structure is the subthalamic nucleus. The subthalamus connects to the globus pallidus, a basal nucleus of the telencephalon. Structure The subthalamus is locate .... References External links * {{Authority control Thalamic connections Basal ganglia connections ...
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Lenticular Fasciculus
The lenticular fasciculus is a tract connecting the globus pallidus (internus) to the thalamus and is a part of the thalamic fasciculus. It is synonymous with field H2 of Forel. The thalamic fasciculus (composed of both the lenticular fasciculus and ansa lenticularis) runs to the thalamus The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, .... Basically, it is part of a pathway that connects the globus pallidus and the thalamus. Lesions in this area can result in dyskinesias such as chorea-like movements. External links * https://web.archive.org/web/20070419222336/http://www.endotext.org/neuroendo/neuroendo3b/neuroendo3b_2.htm (see figure #12) * https://web.archive.org/web/20080504234454/http://isc.temple.edu/neuroanatomy/lab/atlas/mdbg/ {{Authority control Brainstem Thalamus ...
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Fields Of Forel
The fields of Forel are areas in a deep part of the brain known as the diencephalon. They are below the thalamus and consist of three defined, white matter areas of the subthalamus. These three regions are also named "H fields": *Field H1, is the thalamic fasciculus, a horizontal white matter tract composed of the ansa lenticularis, lenticular fasciculus, and cerebellothalamic tracts between the subthalamus and the thalamus. These fibers are projections to the ventral anterior and ventral lateral thalamus from the basal ganglia ( globus pallidus) and the cerebellum. H1 is separated from H2 by the zona incerta. *Field H2 (synonymous with lenticular fasciculus) is also made up of projections from the pallidum to the thalamus, but these course the subthalamic nucleus (dorsal). *Field H (sometimes called field H3) is a large zone of mixed grey and white matter from the pallidothalamic tracts of the lenticular fasciculus and the ansa lenticularis which combine in an area just in fron ...
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Thalamic Fasciculus
The thalamic fasciculus is a component of the subthalamus. It is synonymous with field H1 of Forel. Nerve fibres form a tract containing cerebellothalamic (crossed) and pallidothalamic (uncrossed) fibres, that is insinuated between the thalamus and the zona incerta. The thalamic fasciculus consists of fibers from the ansa lenticularis and from the lenticular fasciculus, coming from different portions of the medial globus pallidus, before they jointly enter the ventral anterior nucleus of the thalamus The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, .... References External links * http://www.meddean.luc.edu/lumen/MedEd/Neuro/frames/nlDEs/nl06fr.htm * https://web.archive.org/web/20070419222336/http://www.endotext.org/neuroendo/neuroendo3b/neuroendo3b_2.htm (see figure #12) * https ...
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Globus Pallidus
The globus pallidus (GP), also known as paleostriatum or dorsal pallidum, is a subcortical structure of the brain. It consists of two adjacent segments, one external, known in rodents simply as the globus pallidus, and one internal, known in rodents as the entopeduncular nucleus. It is part of the telencephalon, but retains close functional ties with the subthalamus in the diencephalon – both of which are part of the extrapyramidal motor system. The globus pallidus is a major component of the basal ganglia, with principal inputs from the striatum, and principal direct outputs to the thalamus and the substantia nigra. The latter is made up of similar neuronal elements, has similar afferents from the striatum, similar projections to the thalamus, and has a similar synaptology. Neither receives direct cortical afferents, and both receive substantial additional inputs from the intralaminar thalamus. Globus pallidus is Latin for "pale globe". Structure Pallidal nuclei are ma ...
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Internal Capsule
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the globus pallidus. The internal capsule contains both ascending and descending axons, going to and coming from the cerebral cortex. It also separates the caudate nucleus and the putamen in the dorsal striatum, a brain region involved in motor and reward pathways. The corticospinal tract constitutes a large part of the internal capsule, carrying motor information from the primary motor cortex to the lower motor neurons in the spinal cord. Above the basal ganglia the corticospinal tract is a part of the corona radiata. Below the basal ganglia the tract is called cerebral crus (a part of the cerebral peduncle) and below the pons it is referred to as the corticospinal tract. Structure The internal capsule consists of three parts and is V-shap ...
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Zona Incerta
The zona incerta (ZI) is a horizontally elongated region of gray matter in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown, though several potential functions related to "limbic–motor integration" have been proposed, such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It has also been identified as a promising deep brain stimulation therapy target for treating Parkinson's disease. Its existence was first described by Auguste Forel in 1877 as a "region of which nothing certain can be said". A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the "zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks." Structure ...
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