Pulmonary Carcinoid Tumour

	Pulmonary Carcinoid Tumour Pulmonary carcinoid tumour is a neuroendocrine tumour of the lung. There are two types: * Typical pulmonary carcinoid tumour * Atypical pulmonary carcinoid tumour Atypical pulmonary carcinoid tumour is a subtype of pulmonary carcinoid tumor. It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung. It is also known as "atypical lung carcinoid tumour", " atypica ... References External links Lung carcinoids (cancer.org) Pulmonary tumour {{neoplasm-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Atypical Pulmonary Carcinoid Tumour Atypical pulmonary carcinoid tumour is a subtype of pulmonary carcinoid tumor. It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung. It is also known as "atypical lung carcinoid tumour", " atypical lung carcinoid" or "moderately differentiated neuroendocrine carcinoma". It is a more aggressive than typical carcinoid tumors: nodal metastases in 70% vs. 5%. The 5 year survival is 49-69%. Atypical carcinoid tumors have increased mitotic activity (2-10 per 10 HPF), nuclear pleomorphism or foci of necrosis. __TOC__ Morphological differential diagnosis * Typical pulmonary carcinoid tumor Typical pulmonary carcinoid tumour is a subtype of pulmonary carcinoid tumour. It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung. Signs and symptoms Lung carcinoids typically present with a coug ... Typical pulmonary carcinoid lacks comedo-like necrosis, and has < 0.2 mitotic figures/HPF. [...More Info...] [...Related Items...] OR:** [Wikipedia] [Google] [Baidu]
picture info	Neuroendocrine Tumour Neuroendocrine tumors (NETs) are neoplasm A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...s that arise from cells of the endocrine (hormonal) and nervous systems. They most commonly occur in the intestine, where they are often called carcinoid tumors, but they are also found in the pancreas, lung, and the rest of the body. Although there are many kinds of NETs, they are treated as a group of tissue because the cells of these neoplasms share common features, such as looking similar, having special secretory granules, and often producing biogenic amines and polypeptide hormones. Classification WHO The World Health Organization (WHO) classification scheme places neuroendocrine tumors into three main categories, which emphasize the Grading (tumors), tumor grade rather than the anato ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Lung The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the air and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their different muscles to support and foster breathing. In earlier tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the main muscle of respiration that drives breathing is the diaphragm. The lungs also provide airflow that makes vocal sounds including human speech possible. Humans have two lungs, one on the left and on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Typical Pulmonary Carcinoid Tumour Typical pulmonary carcinoid tumour is a subtype of pulmonary carcinoid tumour. It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung. Signs and symptoms Lung carcinoids typically present with a cough or hemoptysis. Findings may closely mimic malignant tumours of the lung, i.e. lung cancer. Diagnosis The definitive diagnosis is rendered by a microscopic examination, after excision. Typical carcinoids have cells with stippled chromatin and a moderate quantity of cytoplasm. They typically have few mitoses and lack necrosis. By definition, they are greater than 4 mm in largest dimension; smaller lesions are referred to as ''pulmonary carcinoid tumourlets''. The differential diagnosis of typical pulmonary carcinoid tumour includes: ''atypical pulmonary carcinoid tumour'', ''pulmonary carcinoid tumourlet'' and ''lung adenocarcinoma''. Image: Lung carcinoid - very high mag.jpg , Very high magnification File:Typical carcino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]