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Pox
Pox may refer to: Diseases *Poxviridae, a family of viruses *Buffalopox, a disease of buffaloes *Camelpox, a disease of camels *Canarypox, a disease of wild and captive birds *Chickenpox, a highly contagious illness caused by a primary infection with varicella zoster virus (VZV) *Cowpox, a rodent disease that can infect cattle, and is also transmissible to humans; used for vaccination against smallpox *Dogpox, an infection of canines *Fowlpox, an infectious disease of poultry *Goatpox, an infectious disease of goats *Horsepox, an infectious disease of horses *Mpox, an infectious rodent disease that can infect primates *Mousepox, an iatrogenic infectious disease of laboratory mice *Myxomatosis, "wild rabbitpox", an infectious disease of wild rabbits *Pigeonpox, an infectious disease of pigeons *Plumpox, the most devastating viral disease of stone fruit from the genus “Prunus” *Quokkapox a disease caused by the Quokkapox virus, also called marsupialpox *Rabbitpox, an iatrogenic ...
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Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their ...
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Hemorrhagic Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their s ...
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Mpox
Mpox (formerly known as monkeypox) is an infectious viral disease that can occur in humans and some other animals. Symptoms include a rash that forms blisters and then crusts over, fever, and swollen lymph nodes. The illness is usually mild and most of those infected will recover within a few weeks without treatment. The time from exposure to onset of symptoms ranges from five to twenty-one days and symptoms typically last from two to four weeks. Cases may be severe, especially in children, pregnant women or people with suppressed immune systems. The disease is caused by the monkeypox virus, a zoonotic virus in the genus ''Orthopoxvirus''. The variola virus, the causative agent of smallpox, is also in this genus. Human-to-human transmission can occur through direct contact with infected skin or body fluids, including sexual contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. It may spread from infected animals by handl ...
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Chickenpox
Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV). The disease results in a characteristic skin rash that forms small, itchy blisters, which eventually scab over. It usually starts on the chest, back, and face. It then spreads to the rest of the body. The rash and other symptoms, such as fever, tiredness, and headaches, usually last five to seven days. Complications may occasionally include pneumonia, inflammation of the brain, and bacterial skin infections. The disease is usually more severe in adults than in children. Chickenpox is an airborne disease which spreads easily from one person to the next through the coughs and sneezes of an infected person. The incubation period is 10–21 days, after which the characteristic rash appears. It may be spread from one to two days before the rash appears until all lesions have crusted over. It may also spread through contact with the blisters. Tho ...
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Cowpox
Cowpox is an infectious disease caused by the ''cowpox virus'' (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more often (though overall rarely) from infected cats. The hands and face are most frequently affected and the spots are generally very painful. The virus, part of the genus '' Orthopoxvirus'', is closely related to the ''vaccinia'' virus. The virus is zoonotic, meaning that it is transferable between species, such as from cat to human. The transferral of the disease was first observed in dairymaids who touched the udders of infected cows and consequently developed the signature pustules on their hands.Vanessa Ngan, "Viral and Skin Infections"
2009
Cowpox is more com ...
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Poxviridae
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ...
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Horsepox
''Orthopoxvirus'' is a genus of viruses in the family ''Poxviridae'' and subfamily ''Chordopoxvirinae''. Vertebrates, including mammals and humans, and arthropods serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and monkeypox. The most widely known member of the genus is '' Variola virus'', which causes smallpox. It was eradicated globally by 1977, through the use of ''Vaccinia virus'' as a vaccine. The most recently described species is the ''Alaskapox virus'', first isolated in 2015. Microbiology Structure Orthopoxviruses are enveloped with brick-shaped geometries and virion dimensions around 200 nm wide and 250 nm long. Genome Member viruses have linear DNA genomes around 170–250 kb in length. Lifecycle Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host glycosaminoglycans (GAGs), which mediate cellular ...
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Camelpox
Camelpox is a disease of camels caused by the camelpox virus (CMPV) of the family ''Poxviridae'', subfamily ''Chordopoxvirinae'', and the genus ''Orthopoxvirus''. It causes skin lesions and a generalized infection. Approximately 25% of young camels that become infected will die from the disease, while infection in older camels is generally more mild. Although rare, the infection may spread to the hands of those that work closely with camels. Cause The camelpox virus that causes camelpox is an orthopoxvirus that is very closely related to the variola virus that causes smallpox. It is a large, brick-shaped, enveloped virus that ranges in size from 265–295 nm. The viral genetic material is contained in a linear double-stranded DNA consisting of 202,182 tightly packed base pairs. The DNA is encased in the viral core. Two lateral bodies are found outside the viral core, and are believed to hold the enzymes required for viral reproduction. The camelpox virus most often affe ...
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Canarypox
Canarypox virus (CNPV) is an ''Avipoxvirus'' and etiologic agent of canarypox, a disease of wild and captive birds that can cause significant losses. Canarypox can enter human cells, but it cannot survive and multiply in human cells. There is a live viral vaccine available which may have beneficial properties against human cancer when used as a mammalian expression vector. (ATCvet code: ). Furthermore, the POXIMUNE® C vaccine does offer direct protection against CNPV in susceptible birds. Generally CNPV is considered a disease of songbirds, such as canaries, magpies and nightingales, and is associated with higher mortality rates when compared to other avian pox viruses. In some instances, mortality approaches 100%. Avian pox viruses also cause significant economic losses in domestic poultry and remain a problem in the conservation of endemic bird species inhabiting islands. The general symptoms of CNPV are similar to those of other species of avian pox viruses and are charac ...
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Fowlpox
Fowlpox is the worldwide disease of poultry caused by viruses of the family ''Poxviridae'' and the genus ''Avipoxvirus''. The viruses causing fowlpox are distinct from one another but antigenically similar, possible hosts including chickens, turkeys, quail, canaries, pigeons, and many other species of birds. There are two forms of the disease. The first is spread by biting insects (especially mosquitoes) and wound contamination and causes lesions on the comb, wattles, and beak. Birds affected by this form usually recover within a few weeks. It can also be transmitted via inhalation or ingestion of dust (or dander, representing virus-infected cells shed from cutaneous lesions), or aerosols, leading to the 'diphtheritic form' of the disease, with lesions on the mucous membranes of the mouth, pharynx, larynx, and sometimes trachea. The second form is spread by inhalation of the virus and causes a diphtheritic membrane to form in the mouth, pharynx, larynx, and sometimes the trache ...
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Turkeypox
''Turkeypox virus'' is a virus of the family ''Poxviridae'' and the genus ''Avipoxvirus'' that causes turkeypox. It is one of the most common diseases in the wild turkey (''Meleagris gallopavo'') population. Turkeypox, like all avipoxviruses, is transmitted either through skin contact or by arthropods (typically mosquitos) acting as mechanical vectors. ''Turkeypox virus'' was first reported in a turkey flock in New York by E.L. Burnett, and may be identified by nodular proliferative skin lesions on the non-feathered parts of the body and in the fibrino-necrotic and proliferative lesions in the mucous membrane of the upper respiratory tract. Viral classification Turkeypox virus is a member of the family ''Poxviridae'' and is in the genus ''Avipoxvirus''. There are currently 9 other species within this genus: ''Fowlpox'' virus, ''Juncopox'' virus, ''Mynahpox'' virus, ''Psittacinepox'' virus, ''Sparrowpox'' virus, ''Starlingpox'' virus, ''Pigeonpox'' virus, ''Canarypox'' virus an ...
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Sheeppox
Sheeppox (or sheep pox, known as in Latin, in French, in German) is a highly contagious disease of sheep caused by a poxvirus different from the benign orf (or contagious ecthyma). This virus is in the family ''Poxviridae'' and genus ''Capripoxvirus''. ''Sheeppox virus'' (SPV) is the most severe of all the animal pox diseases and can result in some of the most significant economic consequences due to poor wool and leather quality. Goatpox is a similar disease of goats, caused by a virus antigenically distinct from ''sheeppox virus''. Virology Structure Sheeppox virus is approximately 150 kbp and shares 96% and 97% nucleotide identity with goatpox virus and lumpy skin disease virus, respectively. This virus has a linear, dsDNA genome and is thus apart of group I according to the Baltimore Classification System. The virus has a complex coat and capsid symmetry. Host The hosts for sheeppox virus are all breeds of wild and domesticated sheep. However, those animals native t ...
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