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Postcoital Test
The postcoital test (PCT), also known as the Sims test, Huhner test or Sims–Huhner test, is a test in the evaluation of infertility. The test examines interaction between spermatozoon, sperm and mucus of the cervix. The PCT examines sperm survival in cervical mucus and determines whether sperm are migrating into the female reproductive system. It does not predict whether pregnancy can occur. The test is performed 1 to 2 days before ovulation, when estrogen-stimulated cervical mucus is abundant. Basal body temperatures or the midcycle luteinizing hormone surge may be used to determine the timing of the PCT. Mucus is withdrawn from the endocervical canal within 8 hours of coitus and examined. The presence of any forwardly motile sperm in alkaline mucus suggests adequate coital technique and a normal cervical mucus–sperm interaction. Procedure The PCT is scheduled close to ovulation when mucus is abundant, and the infertile couple is asked to have sexual intercourse, preferably ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infertility
Infertility is the inability of a person, animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects). It is the normal state of a human child or other young offspring, because they have not undergone puberty, which is the body's start of reproductive capacity. In humans, infertility is the inability to become pregnant after one year of unprotected and regular sexual intercourse involving a male and female partner.Chowdhury SH, Cozma AI, Chowdhury JH. Infertility. Essentials for the Canadian Medical Licensing Exam: Review and Prep for MCCQE Part I. 2nd edition. Wolters Kluwer. Hong Kong. 2017. There are many causes of infertility, including some that medical intervention can treat. Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. Many more couples, however, experience involu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spermatozoon
A spermatozoon (; also spelled spermatozoön; ; ) is a motile sperm cell, or moving form of the haploid cell that is the male gamete. A spermatozoon joins an ovum to form a zygote. (A zygote is a single cell, with a complete set of chromosomes, that normally develops into an embryo.) Sperm cells contribute approximately half of the nuclear genetic information to the diploid offspring (excluding, in most cases, mitochondrial DNA). In mammals, the sex of the offspring is determined by the sperm cell: a spermatozoon bearing an X chromosome will lead to a female (XX) offspring, while one bearing a Y chromosome will lead to a male (XY) offspring. Sperm cells were first observed in Antonie van Leeuwenhoek's laboratory in 1677. Mammalian spermatozoon structure, function, and size Humans The human sperm cell is the reproductive cell in males and will only survive in warm environments; once it leaves the male body the sperm's survival likelihood is reduced and it may die, thereby dec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervix
The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes during pregnancy. The narrow, central cervical canal runs along its entire length, connecting the uterine cavity and the lumen of the vagina. The opening into the uterus is called the internal os, and the opening into the vagina is called the external os. The lower part of the cervix, known as the vaginal portion of the cervix (or ectocervix), bulges into the top of the vagina. The cervix has been documented anatomically since at least the time of Hippocrates, over 2,000 years ago. The cervical canal is a passage through which sperm must travel to fertilize an egg cell after sexual intercourse. Several methods of contraception, including cervical caps and cervical diaphragms, aim to block or prevent the passage of sperm through the cervical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervical Mucus
The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes during pregnancy. The narrow, central cervical canal runs along its entire length, connecting the uterine cavity and the lumen of the vagina. The opening into the uterus is called the internal os, and the opening into the vagina is called the external os. The lower part of the cervix, known as the vaginal portion of the cervix (or ectocervix), bulges into the top of the vagina. The cervix has been documented anatomically since at least the time of Hippocrates, over 2,000 years ago. The cervical canal is a passage through which sperm must travel to fertilize an egg cell after sexual intercourse. Several methods of contraception, including cervical caps and cervical diaphragms, aim to block or prevent the passage of sperm through the cervical can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basal Body Temperature
Basal body temperature (BBT or BTP) is the lowest body temperature attained during rest (usually during sleep). It is usually estimated by a temperature measurement immediately after awakening and before any physical activity has been undertaken. This will lead to a somewhat higher value than the true BBT. In women, ovulation causes a sustained increase of at least in BBT. Monitoring BBTs is one way of estimating the day of ovulation. The tendency of a woman to have lower temperatures before ovulation, and higher temperatures afterwards, is known as a biphasic temperature pattern. Charting this pattern may be used as a component of fertility awareness. The BBT of men is comparable to the BBT of women in their follicular phase. Hormonal causes of biphasic patterns The higher levels of estrogen present during the pre-ovulatory (follicular) phase of the menstrual cycle lower BBTs. The higher levels of progesterone released by the corpus luteum after ovulation raise BBTs. Af ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteinizing Hormone
Luteinizing hormone (LH, also known as luteinising hormone, lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. In females, an acute rise of LH known as an LH surge, triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell–stimulating hormone (ICSH), it stimulates Leydig cell production of testosterone. It acts synergistically with follicle-stimulating hormone (Follicle-stimulating hormone, FSH). Structure LH is a heteroprotein dimer, dimeric glycoprotein. Each monomeric unit is a glycoprotein molecule; one alpha and one beta subunit make the full, functional protein. Its structure is similar to that of the other glycoprotein hormones, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovulation
Ovulation is the release of eggs from the ovaries. In women, this event occurs when the ovarian follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be fertilized by sperm. In addition, the uterine lining ( endometrium) is thickened to be able to receive a fertilized egg. If no conception occurs, the uterine lining as well as the egg will be shed during menstruation. Process Ovulation occurs about midway through the menstrual cycle, after the follicular phase. The days in which a person is most fertile can be calculated based on the date of the last menstrual period and the length of a typical menstrual cycle. The few days surrounding ovulation (from approximately days 10 to 18 of a 28-day cycle), constitute the most fertile phase. The time from the beginning of the last menstrual period (LMP) until ovulation is, on average, 14.6 days, but with substantial variation among females and betwe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sexual Intercourse
Sexual intercourse (or coitus or copulation) is a sexual activity typically involving the insertion and thrusting of the penis into the vagina for sexual pleasure or reproduction.Sexual intercourse most commonly means penile–vaginal penetration for sexual pleasure or sexual reproduction; dictionary sources state that it especially means this, and scholarly sources over the years agree. See, for example; * * * * * * * * * This is also known as vaginal intercourse or vaginal sex. Other forms of penetrative sexual intercourse include anal sex (penetration of the anus by the penis), oral sex (penetration of the mouth by the penis or oral penetration of the female genitalia), fingering (sexual penetration by the fingers) and penetration by use of a dildo (especially a strap-on dildo). These activities involve physical intimacy between two or more individuals and are usually used among humans solely for physical or emotional pleasure and can contribute to human bonding. Ther ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fern Test
The fern test is a medical laboratory test used in obstetrics and gynecology. The name refers to the detection of a characteristic "fern like" pattern of vaginal secretions when a specimen is allowed to dry on a glass slide and is viewed under a low-power microscope. The fern test is most commonly used to provide evidence of the presence of amniotic fluid and is used in obstetrics to detect preterm premature rupture of membranes and/or the onset of labor. It also may provide indirect evidence of ovulation and fertility, although it does not predict the time of ovulation. Patrick Duff, MD (2016). Preterm premature (prelabor) rupture of membranes. In Vanessa A Barss, MD, FACOG (Ed.), ''uptodate'' Retrieved from http://www.uptodate.com/ Ferning was first described in the field of gynecology in 1945 by Georgios Papanikolaou, inventor of the pap smear, as a test for ovulation during a normal menstrual cycle. Papanicolaou GN. Mucus test. Anat Rec. 1945;91:293. When high levels of estroge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evidence-based Medicine
Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients". The aim of EBM is to integrate the experience of the clinician, the values of the patient, and the best available scientific information to guide decision-making about clinical management. The term was originally used to describe an approach to teaching the practice of medicine and improving decisions by individual physicians about individual patients. Background, history and definition Medicine has a long history of scientific inquiry about the prevention, diagnosis, and treatment of human disease. The concept of a controlled clinical trial was first described in 1662 by Jan Baptist van Helmont in reference to the practice of bloodletting. Wrote Van Helmont: The first published report describing the conduct and results of a controlled clinical trial was by James Lind, a Scottish naval surgeon who conducted rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Huhner
Max or MAX may refer to: Animals * Max (dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (English Springer Spaniel), the first pet dog to win the PDSA Order of Merit (animal equivalent of OBE) * Max (gorilla) (1971–2004), a western lowland gorilla at the Johannesburg Zoo who was shot by a criminal in 1997 Brands and enterprises * Australian Max Beer * Max Hamburgers, a fast-food corporation * MAX Index, a Hungarian domestic government bond index * Max Fashion, an Indian clothing brand Computing * MAX (operating system), a Spanish-language Linux version * Max (software), a music programming language * Commodore MAX Machine * Multimedia Acceleration eXtensions, extensions for HP PA-RISC Films * ''Max'' (1994 film), a Canadian film by Charles Wilkinson * ''Max'' (2002 film), a film about Adolf Hitler * ''Max'' (2015 film), an American war drama film Games * '' Dancing Stage Max'', a 2005 game in the ''Dance Dance Revolution'' series * ''DD ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hamster Egg Penetration Test
The hamster zona-free ovum test (HZFO test), or hamster egg-penetration test, or sometimes just hamster test, is an in-vitro test used to study physiological profile of spermatozoa. The primary application of the test is to diagnose male infertility caused by sperm unable to penetrate the ova. The test has limited value, due to expense and a high false negative rate. Procedure In this test, sperm are incubated with several hamster eggs. After seven to twenty hours, the number of sperm penetrations per egg is measured. The hamster eggs have had the zona pellucida, the outer membrane, removed—hence, ''zona-free''. Having all eggs penetrated by multiple sperm is considered to be a positive sign for fertility. Results suggest that men whose sperm fail the hamster test are a third as fertile than those whose sperm pass. Although medical professionals often present the procedure as unable to create an embryo, these claims are not technically correct. If the human sperm succe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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