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Percentage Depth Dose Curve
In radiotherapy, a percentage depth dose curve (PDD) (sometimes ''percent'' depth dose curve) relates the absorbed dose deposited by a radiation beam into a medium as it varies with depth along the axis of the beam. The dose values are divided by the maximum dose, referred to as dmax, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber, since water is very similar to human tissue with regard to radiation scattering and absorption. Percent depth dose (PDD), which reflects the overall percentage of dose deposited as compared to the depth of maximum dose, depends on the depth of interest, beam energy, field size, and SSD (source to surface distance) as follows. Of note, PDD generally refers to depths greater than the depth of maximum dose * PDD ''decreases'' with increasing depth due to the inverse square law and due to attenuation of the radiation beam * PDD ''increases'' w ...
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Radiotherapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue l ...
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Absorbed Dose
Absorbed dose is a dose quantity which is the measure of the energy deposited in matter by ionizing radiation per unit mass. Absorbed dose is used in the calculation of dose uptake in living tissue in both radiation protection (reduction of harmful effects), and radiology (potential beneficial effects for example in cancer treatment). It is also used to directly compare the effect of radiation on inanimate matter such as in radiation hardening. The SI unit of measure is the gray (Gy), which is defined as one Joule of energy absorbed per kilogram of matter. The older, non-SI CGS unit rad, is sometimes also used, predominantly in the USA. Deterministic effects Conventionally, in radiation protection, unmodified absorbed dose is only used for indicating the immediate health effects due to high levels of acute dose. These are tissue effects, such as in acute radiation syndrome, which are also known as deterministic effects. These are effects which are certain to happen in a short ...
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Ionization Chamber
The ionization chamber is the simplest type of gas-filled radiation detector, and is widely used for the detection and measurement of certain types of ionizing radiation, including X-rays, gamma rays, and beta particles. Conventionally, the term "ionization chamber" refers exclusively to those detectors which collect all the charges created by ''direct ionization'' within the gas through the application of an electric field. It only uses the discrete charges created by each interaction between the incident radiation and the gas. Gaseous ionization detectors include ionization chambers and devices that use gas multiplication, namely the proportional counter and the Geiger counter. Ion chambers have a good uniform response to radiation over a wide range of energies and are the preferred means of measuring high levels of gamma radiation. They are widely used in the nuclear power industry, research labs, radiography, radiobiology, and environmental monitoring. Principle of operation ...
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Inverse Square
In science, an inverse-square law is any scientific law stating that a specified physical quantity is inversely proportional to the square of the distance from the source of that physical quantity. The fundamental cause for this can be understood as geometric dilution corresponding to point-source radiation into three-dimensional space. Radar energy expands during both the signal transmission and the reflected return, so the inverse square for both paths means that the radar will receive energy according to the inverse fourth power of the range. To prevent dilution of energy while propagating a signal, certain methods can be used such as a waveguide, which acts like a canal does for water, or how a gun barrel restricts hot gas expansion to one dimension in order to prevent loss of energy transfer to a bullet. Formula In mathematical notation the inverse square law can be expressed as an intensity (I) varying as a function of distance (d) from some centre. The intensity is ...
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Dosimetry
Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation. Internal dosimetry assessment relies on a variety of monitoring, bio-assay or radiation imaging techniques, whilst external dosimetry is based on measurements with a dosimeter, or inferred from measurements made by other radiological protection instruments. Dosimetry is used extensively for radiation protection and is routinely applied to monitor occupational radiation workers, where irradiation is expected, or where radiation is unexpected, such as in the aftermath of the Three Mile Island, Chernobyl or Fukushima radiological release incidents. The public dose take-up is measured and calculated from a variety of indicators such as ambient measure ...
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Dose Profile
In external beam Radiotherapy, transverse and longitudinal dose measurements are taken by a radiation detector in order to characterise the radiation beams from medical linear accelerators. Typically, an ionisation chamber and water phantom are used to create these radiation dose profiles. Water is used due to its tissue equivalence. Transverse dose measurements are performed in the x (crossplane) or y (inplane) directions perpendicular to the radiation beam, and at a given depth (z) in the phantom. These are known as dose profiles. Dose measurements taken along the z direction create radiation dose distribution known as a depth-dose curve. See also *Dosimetry *Percentage depth dose curve In radiotherapy, a percentage depth dose curve (PDD) (sometimes ''percent'' depth dose curve) relates the absorbed dose deposited by a radiation beam into a medium as it varies with depth along the axis of the beam. The dose values are divided by t ... References {{Reflist Cancer treatments ...
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Radiation Therapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue ...
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