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Pentamer
A pentamer is an entity composed of five sub-units. In chemistry, it applies to molecules made of five monomers. In biochemistry, it applies to macromolecules, in particular to pentameric proteins, made of five proteic sub-units. In microbiology, a pentamer is one of the proteins composing the polyhedral protein shell that encloses the bacterial micro-compartments known as carboxysomes. In immunology, an MHC pentamer is a reagent used to detect antigen-specific CD8+ T cells. See also * penta prefix * -mer suffix * ''Pentamerous Metamorphosis'', an album by Global Communication * Pentamery (botany), having five parts in a distinct whorl of a plant structure * Pentamerous can also refer to animals, such as crinoids Crinoids are marine animals that make up the class Crinoidea. Crinoids that are attached to the sea bottom by a stalk in their adult form are commonly called sea lilies, while the unstalked forms are called feather stars or comatulids, which are ... Oligomer ...
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Pentamerous Metamorphosis
''Pentamerous Metamorphosis'' is an album by Global Communication originally released in 1993 on Dedicated Records. It is a reworking of the ''Blood Music'' album by Chapterhouse and was originally only available as a bonus CD bundled with the Chapterhouse album. It was rereleased as a standalone album in 1998. Track listing 1993 Original #"Alpha Phase" – 16:39 #"Beta Phase" – 10:49 (mainly a remix of Chapterhouse's ''Don't Look Now'') #"Gamma Phase" – 11:45 (mainly a remix of Chapterhouse's ''There's Still Life'' and ''Deli'') #"Delta Phase" – 10:41 (mainly a remix of Chapterhouse's ''We Are the Beautiful'') #"Epsilon Phase" – 11:18 (mainly a remix Chapterhouse's ''Love Forever'') 1998 Remaster/Reissue #"Alpha Phase" – 16:47 #"Beta Phase" – 10:46 #"Gamma Phase" – 11:50 #"Delta Phase" – 10:14 #"Epsilon Phase" – 11:26 Notes The 1998 re-release was remastered and had minor changes to two tracks: (Beta Phase) to remove an uncleared samp ...
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MHC Multimer
MHC multimers are oligomeric forms of MHC molecules, designed to identify and isolate T-cells with high affinity to specific antigens amid a large group of unrelated T-cells. Multimers generally range in size from dimers to octamers; however, some companies use even higher quantities of MHC per multimer. Multimers may be used to display class 1 MHC, class 2 MHC, or nonclassical molecules (e.g. CD1d) from species such as monkeys, mice, and humans. Background Since T-cell receptors have a low affinity for their MHC counterparts, it was historically problematic to label T cells effectively using single MHC-T-cell interactions. However, in 1996 it was proposed by John Altman to use a complex of multiple MHC molecules to form a more stable bond between corresponding T-cells.Bakker, Arnold; Schumacher, Tom. "MHC Multimer Technology: Current Status and Future Prospects," ''Current Opinion in Immunology'', Vol. 17, No. 4 (August 2005), pp. 428-433. Production The most commonly used M ...
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Pentameric Protein
A pentameric protein is a quaternary protein structure that consists of five protein subunits. Examples Ligand-gated ion channels Five sub-units come together to form a channel. Each channel consist of two alpha chain, one beta, one gamma and one delta chain. These five chains assemble together (along with certain receptors like protons or acetylcholine) forming the structure of the channel. A ligand-gated ion channel on the post-synaptic junction of the muscle-end plate is an example of such a channel. They are acetylcholine-operated ion channels, which means that acetylcholine brings about a conformational change. The channel allows the free movement of the cations like Na and K when acetylcholine binds to its receptors. Viral capsids Many viral capsids are formed by hexameric and pentameric proteins. Such capsids are assigned a triangulation number (T-number) which describe relation between the number of pentagons and hexagons. Carboxysomes Protein enclosing bacterial organe ...
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Carboxysome
Carboxysomes are bacterial microcompartments (BMCs) consisting of polyhedral protein shells filled with the enzymes ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO)—the predominant enzyme in carbon fixation and the rate limiting enzyme in the Calvin cycle—and carbonic anhydrase. Carboxysomes are thought to have evolved as a consequence of the increase in oxygen concentration in the ancient atmosphere; this is because oxygen is a competing substrate to carbon dioxide in the RuBisCO reaction. To overcome the inefficiency of RuBisCO, carboxysomes concentrate carbon dioxide inside the shell by means of co-localized carbonic anhydrase activity, which produces carbon dioxide from the bicarbonate that diffuses into the carboxysome. The resulting concentration of carbon dioxide near RuBisCO decreases the proportion of ribulose-1,5-bisphosphate oxygenation and thereby avoids costly photorespiratory reactions. The surrounding shell provides a barrier to carbon dioxid ...
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Merosity
Merosity (from the greek "méros," which means "having parts") refers to the number of component parts in a distinct whorl of a plant structure. The term is most commonly used in the context of a flower where it refers to the number of sepals in a whorl of the calyx, the number of petals in a whorl of the corolla, the number of stamens in a whorl of the androecium, or the number of carpels in a whorl of the gynoecium. The term may also be used to refer to the number of leaves in a leaf whorl. The adjective ''n''-merous refers to a whorl of ''n'' parts, where ''n'' is any integer greater than one. In nature, five or three parts per whorl have the highest frequency of occurrence, but four or two parts per whorl are not uncommon. Be aware that two consecutive whorls of dimerous petals are often mistaken for tetramerous petals. If all of the whorls in a given floral arrangement have the same merosity, the flower is said to be isomerous, otherwise the flower is anisomerous. For exampl ...
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Crinoids
Crinoids are marine animals that make up the class Crinoidea. Crinoids that are attached to the sea bottom by a stalk in their adult form are commonly called sea lilies, while the unstalked forms are called feather stars or comatulids, which are members of the largest crinoid order, Comatulida. Crinoids are echinoderms in the phylum Echinodermata, which also includes the starfish, brittle stars, sea urchins and sea cucumbers. They live in both shallow water and in depths as great as . Adult crinoids are characterised by having the mouth located on the upper surface. This is surrounded by feeding arms, and is linked to a U-shaped gut, with the anus being located on the oral disc near the mouth. Although the basic echinoderm pattern of fivefold symmetry can be recognised, in most crinoids the five arms are subdivided into ten or more. These have feathery pinnules and are spread wide to gather planktonic particles from the water. At some stage in their lives, most crinoids have a ...
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Subunit (other)
Subunit may refer to: * Subunit HIV vaccine, a class of HIV vaccine *Protein subunit, a protein molecule that assembles with other protein molecules *Monomer, a molecule that may bind chemically to other molecules to form a polymer * Sub-subunit, a military subunit is a component or subordinate element of a unit (military) * Subunit (format), test reporting and controlling protocol See also *Unit (other) Unit may refer to: Arts and entertainment * UNIT, a fictional military organization in the science fiction television series ''Doctor Who'' * Unit of action, a discrete piece of action (or beat) in a theatrical presentation Music * ''Unit'' (al ...
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Monomer
In chemistry, a monomer ( ; ''mono-'', "one" + '' -mer'', "part") is a molecule that can react together with other monomer molecules to form a larger polymer chain or three-dimensional network in a process called polymerization. Classification Monomers can be classified in many ways. They can be subdivided into two broad classes, depending on the kind of the polymer that they form. Monomers that participate in condensation polymerization have a different stoichiometry than monomers that participate in addition polymerization: : Other classifications include: *natural vs synthetic monomers, e.g. glycine vs caprolactam, respectively *polar vs nonpolar monomers, e.g. vinyl acetate vs ethylene, respectively *cyclic vs linear, e.g. ethylene oxide vs ethylene glycol, respectively The polymerization of one kind of monomer gives a homopolymer. Many polymers are copolymers, meaning that they are derived from two different monomers. In the case of condensation polymerizations, the r ...
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T Cell
A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" and CD4+ "helper" T cells. (These are named for the presence of the cell surface proteins CD8 or ...
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Number Prefix
Numeral or number prefixes are prefixes derived from numerals or occasionally other numbers. In English and many other languages, they are used to coin numerous series of words. For example: * unicycle, bicycle, tricycle (1-cycle, 2-cycle, 3-cycle) * dyad, triad (2 parts, 3 parts) * biped, quadruped (2 legs, 4 legs) * September, October, November, December (month 7, month 8, month 9, month 10) * decimal, hexadecimal (base-10, base-16) * septuagenarian, octogenarian (70-79 years old, 80-89 years old) * centipede, millipede (around 100 legs, around 1000 legs) In many European languages there are two principal systems, taken from Latin and Greek, each with several subsystems; in addition, Sanskrit occupies a marginal position. There is also an international set of metric prefixes, which are used in the metric system and which for the most part are either distorted from the forms below or not based on actual number words. Table of number prefixes in English In the following pr ...
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