Pendetide
Pendetide (GYK-DTPA) is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K). Use The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111 Indium-111 (111In) is a radioactive isotope of indium (In). It decays by electron capture to stable cadmium-111 with a half-life of 2.8 days. Indium-111 chloride (111InCl) solution is produced by proton irradiation of a cadmium target (112Cd(p,2n) .... The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours. * Indium (111In) capromab pendetide (prostate cancer) * Indium (111In) satumomab pendetide (other cancer types) References Chelating agents Chelating agents used as drugs Carboxylic acids Peptides {{pharma-stub ...
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