Ornithinaemia

	Ornithinaemia Ornithinaemia is a blood disorder characterized by high levels of ornithine. Also known as hyperornithinemia, it may be associated with psychomotor retardation or epileptic Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ... episodes.{{cite journal, last=Wfirst=T, author2=Pollitt, R, title=Psychomotor retardation, epileptic and stuporous attacks, irritability and ataxia associated with ammonia intoxication, high blood ornithine levels and increased homocitruline in the urine., journal=Proceedings of the Royal Society of Medicine, date=Mar 1973, volume=66, issue=3, pages=221, doi=10.1177/003591577306600306, pmid=4697977, pmc=1644839 References Blood disorders ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Blood Disorder Hematologic diseases are disorders which primarily affect the blood & blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease & complications from chemotherapy or transfusions. Myeloid * Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis) Sickle cell disease Thalassemia ** Methemoglobinemia * Anemias (lack of red blood cells or hemoglobin) Iron-deficiency anemia Megaloblastic anemia * Vitamin B12 deficiency Pernicious anemia * Folate deficiency Hemolytic anemias (destruction of red blood cells) * Genetic disorders of RBC membrane ** Hereditary spherocytosis Hereditary elliptocytosis Congenital dyserythropoietic anemia * Genetic disorders of RBC metabolism ** Glucose-6-phosphate dehydrogenase deficiency (G6PD) Pyruvate kinase deficiency * Immune mediated hemolytic anemia (direct Coombs test is positive) ** Autoimmune hemo ... [...More Info...] [...Related Items...] OR:** [Wikipedia] [Google] [Baidu]
picture info	Ornithine Ornithine is a non-proteinogenic amino acid that plays a role in the urea cycle. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase deficiency. The radical is ornithyl. Role in urea cycle L-Ornithine is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is a central part of the urea cycle, which allows for the disposal of excess nitrogen. Ornithine is recycled and, in a manner, is a catalyst. First, ammonia is converted into carbamoyl phosphate (). Ornithine is converted into a urea derivative at the δ (terminal) nitrogen by carbamoyl phosphate synthetase. Another nitrogen is added from aspartate, producing the denitrogenated fumarate, and the resulting arginine (a guanidinium compound) is hydrolysed back to ornithine, producing urea. The nitrogens of urea come from the ammonia and aspartate, and the nitrogen in ornithine remains intact. Ornithine is not an amino acid coded for by DNA, that is, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Psychomotor Retardation Psychomotor may refer to: * Psychomotor learning, the relationship between cognitive functions and physical movement * Psychomotor retardation, a slowing-down of thought and a reduction of physical movements in an individual * Psychomotor agitation Psychomotor agitation is a symptom in various disorders and health conditions. It is characterized by unintentional and purposeless motions and restlessness, often but not always accompanied by emotional distress. Typical manifestations include ... , a series of unintentional and purposeless motions that stem from mental tension and anxiety of an individual {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain. These episodes can result in physical injuries, either directly such as broken bones or through causing accidents. In epilepsy, seizures tend to recur and may have no immediate underlying cause. Isolated seizures that are provoked by a specific cause such as poisoning are not deemed to represent epilepsy. People with epilepsy may be treated differently in various areas of the world and experience varying degrees of social stigma due to the alarming nature of their symptoms. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity in the cortex of the brain which can be observed in the electroencephalogram (EEG) of an individual. The reason this occurs in most cases of epilepsy is u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]