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Omega-6
Omega-6 fatty acids (also referred to as ω-6 fatty acids or ''n''-6 fatty acids) are a family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the ''n''-6 position, that is, the sixth bond, counting from the methyl end. Health effects One review found that an increased intake of omega‐6 fatty acids has been shown to reduce total serum cholesterol and may reduce myocardial infarction. The same review found no significant change in LDL cholesterol and triglycerides. A 2021 review found that omega 6 supplements do not affect the risk of CVD morbidity and mortality. Dietary sources Dietary sources of omega-6 fatty acids include: * poultry * eggs * nuts * hulled sesame seeds * cereals * durum wheat * whole-grain breads * pumpkin seeds * hemp seeds Vegetable oils Vegetable oils are a major source of omega-6 linoleic acid. Worldwide, more than 100 million metric tons of vegetable oils are extracted annually from palm fruits, soybean ...
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Linoleic Acid
Linoleic acid (LA) is an organic compound with the formula COOH(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups are cis-trans isomerism, ''cis''. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 ''cis''-9,12. A linoleate is a salt (chemistry), salt or ester of this acid. Linoleic acid is a polyunsaturated fatty acid, polyunsaturated omega-6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents. It typically occurs in nature as a triglyceride (ester of glycerol, glycerin) rather than as a free fatty acid. It is one of two essential fatty acids for humans, who must obtain it through their diet, and the most essential, because the body uses it as a base to make the others. The word "linoleic" derives from the Latin ''linum'' "flax" + ''oleum'' "oil", reflecting the fact that it was first isolated from linseed oil. History In 1844, F. Sacc, working at the laboratory of Justus von Liebig, isolated linoleic acid from l ...
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Polyunsaturated Fatty Acids
Polyunsaturated fatty acids (PUFAs) are fatty acids that contain more than one double bond in their backbone. This class includes many important compounds, such as essential fatty acids and those that give drying oils their characteristic property. Polyunsaturated fatty acids can be classified in various groups by their chemical structure: * methylene-interrupted polyenes * conjugated fatty acids * other PUFAs Based on the length of their carbon backbone, they are sometimes classified in two groups: * short chain polyunsaturated fatty acids (SC-PUFA), with 18 carbon atoms * long-chain polyunsaturated fatty acids (LC-PUFA) with 20 or more carbon atoms Dietary sources Types Methylene-interrupted polyenes These fatty acids have 2 or more ''cis'' double bonds that are separated from each other by a single methylene bridge (--). This form is also sometimes called a ''divinylmethane pattern''. The essential fatty acids are all omega-3 and -6 methylene-interrupted fatty ac ...
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Fatty Acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, from 4 to 28. Fatty acids are a major component of the lipids (up to 70% by weight) in some species such as microalgae but in some other organisms are not found in their standalone form, but instead exist as three main classes of esters: triglycerides, phospholipids, and cholesteryl esters. In any of these forms, fatty acids are both important dietary sources of fuel for animals and important structural components for cells. History The concept of fatty acid (''acide gras'') was introduced in 1813 by Michel Eugène Chevreul, though he initially used some variant terms: ''graisse acide'' and ''acide huileux'' ("acid fat" and "oily acid"). Types of fatty acids Fatty acids are classified in many ways: by length, by saturation vs unsaturati ...
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Arachidonic Acid
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6), or 20:4(5,8,11,14). It is structurally related to the saturated arachidic acid found in cupuaçu butter. Its name derives from the New Latin word ''arachis'' (peanut), but peanut oil does not contain any arachidonic acid. Chemistry In chemical structure, arachidonic acid is a carboxylic acid with a 20-carbon chain and four ''cis''-double bonds; the first double bond is located at the sixth carbon from the omega end. Some chemistry sources define 'arachidonic acid' to designate any of the eicosatetraenoic acids. However, almost all writings in biology, medicine, and nutrition limit the term to ''all cis''-5,8,11,14-eicosatetraenoic acid. Biology Arachidonic acid is a polyunsaturated fatty acid present in the phospholipids (especially phosphatidylethanolamine, phosphatidylcholine, and phosphatidylinositides) of membranes of the body's cells, and is abundant in the brain, muscles, an ...
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Rapeseed Oil
Close-up of canola blooms Canola flower Rapeseed oil is one of the oldest known vegetable oils. There are both edible and industrial forms produced from rapeseed, the seed of several cultivars of the plant family Brassicaceae. Historically, it was eaten in limited quantities due to high levels of erucic acid, which is damaging to the cardiac muscle of animals and imparts a bitter taste, and glucosinolates, which made it less nutritious in animal feed. Rapeseed oil can contain up to 54% erucic acid. Canola oil is a food-grade version derived from rapeseed cultivars bred for low erucic acid content. Also known as low erucic acid rapeseed (LEAR) oil, it has been generally recognized as safe by the United States Food and Drug Administration. Canola oil is limited by government regulation to a maximum of 2% erucic acid by weight in the US and the EU, with special regulations for infant food. These low levels of erucic acid do not cause harm in humans. In commerce, non-food variet ...
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Eicosadienoic Acid
Fatty acid molecular species Mono-unsaturated fatty acid The following fatty acids have one unsaturated bond. Crotonic acid Crotonic acid has 4 carbons, is included in croton oil, and is a ''trans''-2-mono-unsaturated fatty acid. C3H5 CO2H, IUPAC organization name (''E'')-but-2-enoic acid, '' trans '' -but-2-enoic acid, numerical representation 4: 1, n-1, molecular weight 86.09, melting point 72-74 °C, boiling point 180-181 °C, specific gravity 1.027. CAS registry number 107-93-7. Myristoleic Myristoleic acid has 14 carbons, is found in whale blubber, and is a ''cis''-9-monounsaturated fatty acid. C13H25CO2H, IUPAC organization name (''Z'')-tetradec-9-enoic acid, numerical representation 14:1, n-5, molecular weight 226.36, melting point of -4.5 -4 °C. CAS Registry Number 544-64-9. Palmitoleic acid Palmitoleic acid has 16 carbons, is found in cod liver oil, sardine oil, and herring oil, and is a ''cis''9-monounsaturated fatty acid. C15H29 ...
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Calendic Acid
Calendic acid (sometimes α-calendic acid) is an unsaturated fatty acid, named for the pot marigold (''Calendula officinalis''), from which it is obtained. It is chemically similar to the conjugated linoleic acids; laboratory work suggests it may have similar ''in vitro'' bioactivities. Biosynthesis Calendic acid is an omega-6 fatty acid. though not usually listed with this group. Calendic acid is synthesised in ''Calendula officinalis'' from linoleate by an unusual Δ12-oleate desaturase A fatty acid desaturase is an enzyme that removes two hydrogen atoms from a fatty acid, creating a carbon/carbon double bond. These desaturases are classified as: * Delta - indicating that the double bond is created at a fixed position from the ... (a FAD 2 variant) that converts the ''cis''-double bond at position 9 to a ''trans'',''trans''-conjugated double bond system. An ''all-trans'' beta isomer has been described. : Effects Calendic acid is the fatty acid responsible for the reductio ...
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USDA
The United States Department of Agriculture (USDA) is the federal executive department responsible for developing and executing federal laws related to farming, forestry, rural economic development, and food. It aims to meet the needs of commercial farming and livestock food production, promotes agricultural trade and production, works to assure food safety, protects natural resources, fosters rural communities and works to end hunger in the United States and internationally. It is headed by the Secretary of Agriculture, who reports directly to the President of the United States and is a member of the president's Cabinet. The current secretary is Tom Vilsack, who has served since February 24, 2021. Approximately 80% of the USDA's $141 billion budget goes to the Food and Nutrition Service (FNS) program. The largest component of the FNS budget is the Supplemental Nutrition Assistance Program (formerly known as the Food Stamp program), which is the cornerstone of USDA's ...
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Sunflower Oil
Sunflower oil is the non-volatile oil pressed from the seeds of the sunflower (''Helianthus annuus''). Sunflower oil is commonly used in food as a frying oil, and in cosmetic formulations as an emollient. Sunflower oil is primarily composed of linoleic acid, a polyunsaturated fat, and oleic acid, a monounsaturated fat. Through plant breeding, selective breeding and manufacturing processes, oils of differing proportions of the fatty acids are produced. The Expeller pressing, expressed oil has a neutral taste profile. The oil contains a large amount of vitamin E. As of 2017, genome analysis and development of hybrid (biology), hybrid sunflowers to increase oil production are under development to meet greater consumer demand for sunflower oil and its commercial varieties. In 2018, Ukraine and Russia together accounted for 53% of the world's production of sunflower oil. Composition Sunflower oil is mainly a triglyceride. The British Pharmacopoeia lists the following profile: ...
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