O-succinylbenzoate Synthase
''o''-Succinylbenzoate synthase (OSBS) () is an enzyme encoded by the menC gene in ''E.coli'', and catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to form 4-(2'-carboxyphenyl)-4-oxobutyrate, also called ''o''-succinylbenzoate or OSB, hence the name of the enzyme. This reaction is the fourth step in the menaquinone biosynthetic pathway, which is used by bacteria to synthesize menaquinone, also known as vitamin K2. Classification OSBS belongs to the muconate lactonizing enzyme subgroup of the enolase superfamily. The List of enzymes, systematic name of this enzyme is (1''R'',6''R'')-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate hydrolyase (2-succinylbenzoate-forming). Other common names include: ''o''-succinylbenzoic acid synthase and OSB synthase. Menaquinone biosynthetic pathway The menaquinone biosynthetic pathway consists of nine enzymatic reactions, ultimately resulting in the synthesis of vitamin K. This pathway is quite s ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  

Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]