Neural Basis Of Synesthesia
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Neural Basis Of Synesthesia
Synesthesia is a neurological condition in which two or more bodily senses are coupled. For example, in a form of synesthesia known as Grapheme → color synesthesia, letters or numbers may be perceived as inherently colored. In another, called number → form synesthesia, numbers are automatically and consistently associated with locations in space. In yet another form of synesthesia, called ordinal linguistic personification, either numbers, days of the week, or months of the year evoke personalities. In other forms of synesthesia, music and other sounds may be perceived as colored or having particular shapes. Recent research has begun to explore the neural basis of these experiences, drawing both on neuroscientific principles and on functional neuroimaging data. Based on these data, two major theories have been proposed concerning the neural basis of synesthesia. Both theories start from the observation that there are dedicated regions of the brain that are specialized for ce ...
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Synesthesia
Synesthesia (American English) or synaesthesia (British English) is a perceptual phenomenon in which stimulation of one sensory or cognitive pathway leads to involuntary experiences in a second sensory or cognitive pathway. People who report a lifelong history of such experiences are known as synesthetes. Awareness of synesthetic perceptions varies from person to person. In one common form of synesthesia, known as grapheme–color synesthesia or color–graphemic synesthesia, letters or numbers are perceived as inherently colored. In spatial-sequence, or number form synesthesia, numbers, months of the year, or days of the week elicit precise locations in space (''e.g.,'' 1980 may be "farther away" than 1990), or may appear as a three-dimensional map (clockwise or counterclockwise). Synesthetic associations can occur in any combination and any number of senses or cognitive pathways. Little is known about how synesthesia develops. It has been suggested that synesthesia dev ...
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Temporal Lobe
The temporal lobe is one of the four Lobes of the brain, major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's Temple (anatomy), temples. Structure The Temple (anatomy)#Etymology, temporal Lobe (anatomy), lobe consists of structures that are vital for declarative or long-term memory. Declarative memory, Declarative (denotative) or Explicit memory, explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). Medial temporal lobe structures that are critical for long-term memory include the hippocampus, along with the surrounding Hippocampal formation, hippocampal region consisting of the Perirhinal cortex, perirhinal, ...
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Functional Neuroimaging
Functional neuroimaging is the use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. It is primarily used as a research tool in cognitive neuroscience, cognitive psychology, neuropsychology, and social neuroscience. Overview Common methods of functional neuroimaging include * Positron emission tomography (PET) * Functional magnetic resonance imaging (fMRI) * Electroencephalography (EEG) * Magnetoencephalography (MEG) * Functional near-infrared spectroscopy (fNIRS) * Single-photon emission computed tomography (SPECT) * Functional ultrasound imaging (fUS) PET, fMRI, fNIRS and fUS can measure localized changes in cerebral blood flow related to neural activity. These changes are referred to as ''activations''. Regions of the brain which are activated when a subject performs a particular task may play a role in the computational neuroscience, n ...
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Single-nucleotide Polymorphism
In genetics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), many publications do not apply such a frequency threshold. For example, at a specific base position in the human genome, the G nucleotide may appear in most individuals, but in a minority of individuals, the position is occupied by an A. This means that there is a SNP at this specific position, and the two possible nucleotide variations – G or A – are said to be the alleles for this specific position. SNPs pinpoint differences in our susceptibility to a wide range of diseases, for example age-related macular degeneration (a common SNP in the CFH gene is associated with increased risk of the disease) or nonalcoholic fatty liver disease (a SNP in the PNPLA3 gene is associated with inc ...
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Chinese Room
The Chinese room argument holds that a digital computer executing a program cannot have a " mind," "understanding" or "consciousness," regardless of how intelligently or human-like the program may make the computer behave. The argument was presented by philosopher John Searle in his paper, "Minds, Brains, and Programs", published in ''Behavioral and Brain Sciences'' in 1980. Similar arguments were presented by Gottfried Leibniz (1714), Anatoly Dneprov (1961), Lawrence Davis (1974) and Ned Block (1978). Searle's version has been widely discussed in the years since. The centerpiece of Searle's argument is a thought experiment known as the ''Chinese room''. The argument is directed against the philosophical positions of functionalism and computationalism, which hold that the mind may be viewed as an information-processing system operating on formal symbols, and that simulation of a given mental state is sufficient for its presence. Specifically, the argument is intended to ref ...
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Understanding
Understanding is a psychological process related to an abstract or physical object, such as a person, situation, or message whereby one is able to use concepts to model that object. Understanding is a relation between the knower and an object of understanding. Understanding implies abilities and dispositions with respect to an object of knowledge that are sufficient to support intelligent behavior. Understanding is often, though not always, related to learning concepts, and sometimes also the theory or theories associated with those concepts. However, a person may have a good ability to predict the behavior of an object, animal or system—and therefore may, in some sense, understand it—without necessarily being familiar with the concepts or theories associated with that object, animal, or system in their culture. They may have developed their own distinct concepts and theories, which may be equivalent, better or worse than the recognized standard concepts and theories of thei ...
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Semantics
Semantics (from grc, σημαντικός ''sēmantikós'', "significant") is the study of reference, meaning, or truth. The term can be used to refer to subfields of several distinct disciplines, including philosophy Philosophy (from , ) is the systematized study of general and fundamental questions, such as those about existence, reason, knowledge, values, mind, and language. Such questions are often posed as problems to be studied or resolved. Some ..., linguistics and computer science. History In English, the study of meaning in language has been known by many names that involve the Ancient Greek word (''sema'', "sign, mark, token"). In 1690, a Greek rendering of the term ''semiotics'', the interpretation of signs and symbols, finds an early allusion in John Locke's ''An Essay Concerning Human Understanding'': The third Branch may be called [''simeiotikí'', "semiotics"], or the Doctrine of Signs, the most usual whereof being words, it is aptly enough ter ...
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Meaning (non-linguistic)
Non-linguistic (or pre-linguistic) meaning is a type of meaning not mediated or perceived through linguistic signs. In linguistics, the concept is used in discussions about whether such meaning is different from meaning expressed through language (i.e. semantics), should play a role in linguistic theory, or to which extent thought and conceptualization is affected by linguistic knowledge (as in the language of thought hypothesis or linguistic relativity). Meaning as internal interpretation The sense that sentient creatures have that the various objects of our universe are linked is commonly referred to as a person's sense of "meaning". This is the sense of meaning at work when asking a person when they leave a theater, "What did that movie mean to you?" In short, the word "meaning" can sometimes be used to describe the ''interpretations'' that people have of the world. Example: "Chunks are pieces of information linked and bound by meaning. (Remembering details vs. getting a ...
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Ideasthesia
Ideasthesia (alternative spelling ideaesthesia) is a neuropsychological phenomenon in which activations of concepts (inducers) evoke perception-like sensory experiences (concurrents). The name comes from the Ancient Greek () and (), meaning 'sensing concepts' or 'sensing ideas'. The notion was introduced by neuroscientist Danko Nikolić as an alternative explanation for a set of phenomena traditionally covered by synesthesia. While ''synesthesia'' meaning 'union of senses' implies the association of two sensory elements with little connection to the cognitive level, empirical evidence indicated that most phenomena linked to synesthesia are in fact induced by semantic representations. That is, the linguistic meaning of the stimulus is what is important rather than its sensory properties. In other words, while synesthesia presumes that both the trigger (inducer) and the resulting experience (concurrent) are of sensory nature, ideasthesia presumes that only the resulting experience ...
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Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sources It occurs naturally in several species of cacti. It is also found in small amounts in certain members of the bean family, Fabaceae, including ''Acacia berlandieri''. However those claims concerning ''Acacia'' species have been challenged and have been unsupported in any additional analysis. History and use Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador. While religious and ceremonial peyote use was widespread in the Aztec empire and northern M ...
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Limbic System
The limbic system, also known as the paleomammalian cortex, is a set of brain structures located on both sides of the thalamus, immediately beneath the medial temporal lobe of the cerebrum primarily in the forebrain.Schacter, Daniel L. 2012. ''Psychology''.sec. 3.20 It supports a variety of functions including emotion, behavior, long-term memory, and olfaction. Emotional life is largely housed in the limbic system, and it critically aids the formation of memories. With a primordial structure, the limbic system is involved in lower order emotional processing of input from sensory systems and consists of the amygdaloid nuclear complex (amygdala), mammillary bodies, stria medullaris, central gray and dorsal and ventral nuclei of Gudden. This processed information is often relayed to a collection of structures from the telencephalon, diencephalon, and mesencephalon, including the prefrontal cortex, cingulate gyrus, limbic thalamus, hippocampus including the parahippocampal gyrus an ...
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Parietal Lobe
The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus. The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe. Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the cortical homunculus (Latin: "little man") in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule and in ...
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