Nepetalactone
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Nepetalactone
Nepetalactone is a name for multiple iridoid analog stereoisomers. Nepetalactones are produced by ''Nepeta cataria'' (catnip) and many other plants belonging to the genus '' Nepeta'', in which they protect these plants from herbivorous insects by functioning as insect repellents. They are also produced by many aphids, in which they are sex pheromones. Nepetalactones are cat attractants, and cause the behavioral effects that catnip induces in domestic cats. However, they affect visibly only about two thirds of adult cats. They produce similar behavioral effects in many other felids, especially in lions and jaguars. In 1941, the research group of Samuel M. McElvain was the first to determine the structures of nepetalactones and several related compounds. Structure and properties Nepetalactone has three chiral centers, two at the fusion of the two rings, and one where the methyl group attaches to the cyclopentane ring. Thus, it has eight (23) stereoisomers. The terms ''cis'' an ...
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Nepetalactone Isomers
Nepetalactone is a name for multiple iridoid analog stereoisomers. Nepetalactones are produced by ''Nepeta cataria'' (catnip) and many other plants belonging to the genus ''Nepeta'', in which they protect these plants from herbivorous insects by functioning as insect repellents. They are also produced by many aphids, in which they are sex pheromones. Nepetalactones are cat attractants, and cause the behavioral effects that catnip induces in domestic cats. However, they affect visibly only about two thirds of adult cats. They produce similar behavioral effects in many other felids, especially in lions and jaguars. In 1941, the research group of Samuel M. McElvain was the first to determine the structures of nepetalactones and several related compounds. Structure and properties Nepetalactone has three chiral centers, two at the fusion of the two rings, and one where the methyl group attaches to the cyclopentane ring. Thus, it has eight (23) stereoisomers. The terms ''cis'' and '' ...
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Catnip
''Nepeta cataria'', commonly known as catnip, catswort, catwort, and catmint, is a species of the genus '' Nepeta'' in the family Lamiaceae, native to southern and eastern Europe, the Middle East, Central Asia, and parts of China. It is widely naturalized in northern Europe, New Zealand, and North America. The common name catmint can also refer to the genus as a whole. The names ''catnip'' and ''catmint'' are derived from the intense attraction about two-thirds of cats have toward it ( alternative plants exist). In addition to its uses with cats, catnip is an ingredient in some herbal teas (or tisanes), and is valued for its sedative and relaxant properties. Description ''Nepeta cataria'' is a short-lived perennial, herbaceous plant that grows to be tall and wide, and that blooms from late spring to autumn. In appearance, ''N. cataria'' resembles a typical member of the mint family of plants, featuring brown-green foliage with the characteristic square stem of the plant ...
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Domestic Cats
The cat (''Felis catus'') is a domestic species of small carnivorous mammal. It is the only domesticated species in the family Felidae and is commonly referred to as the domestic cat or house cat to distinguish it from the wild members of the family. Cats are commonly kept as house pets but can also be farm cats or feral cats; the feral cat ranges freely and avoids human contact. Domestic cats are valued by humans for companionship and their ability to kill rodents. About 60 cat breeds are recognized by various cat registries. The cat is similar in anatomy to the other felid species: they have a strong flexible body, quick reflexes, sharp teeth, and retractable claws adapted to killing small prey. Their night vision and sense of smell are well developed. Cat communication includes vocalizations like meowing, purring, trilling, hissing, growling, and grunting as well as cat-specific body language. Although the cat is a social species, they are a solitary hunter. As a pred ...
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Actinidine
Actinidine is an iridoid produced in nature by a wide variety of plants and animals. It was the first cyclopentanoid monoterpene alkaloid to be discovered. It is one of several compounds that may be extracted from the valerian (''Valeriana officinalis'') root and silver vine ('' Actinidia polygama''), as well as several types of insects in the larval and imaginal stages. Actinidine is a cat attractant, with effects like those of nepetalactone, the active compound found in catnip. Certain species of stick insects, including '' Megacrania batesii'' and ''Megacrania tsudai ''Megacrania'' is a genus of the subfamily Megacraniinae of stick insects. Members of this genus are commonly referred to as "peppermint stick insects", due to the characteristic odor of their defensive spray, as well as the cylindrical, twig-lik ...'', possess a chemical defense mechanism which involves the secretion of an actinidine-containing substance from the prothoracic glands, when threatened by ...
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Nepeta
''Nepeta'' is a genus of flowering plants in the family Lamiaceae. The genus name is reportedly in reference to Nepete, an ancient Etruscan city.Missouri Botanical Garden: ''Nepeta'' × ''faassenii''
Accessed January 10, 2013
There are about 250 species. The genus is to Europe, Asia, and Africa, and has also in North America. Some members of this group are known as

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Insect Repellent
An insect repellent (also commonly called "bug spray") is a substance applied to skin, clothing, or other surfaces to discourage insects (and arthropods in general) from landing or climbing on that surface. Insect repellents help prevent and control the outbreak of insect-borne (and other arthropod-bourne) diseases such as malaria, Lyme disease, dengue fever, bubonic plague, river blindness, and West Nile fever. Pest animals commonly serving as vectors for disease include insects such as flea, fly, and mosquito; and ticks (arachnids). Some insect repellents are insecticides (bug killers), but most simply discourage insects and send them flying or crawling away. Nearly any would be fatal upon reaching the median lethal dose, but classification as an insecticide implies death even at lower doses. Effectiveness Synthetic repellents tend to be more effective and/or longer lasting than "natural" repellents. For protection against mosquito bites, the U.S. Centers for D ...
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Cat Attractant
A cat pheromone is a chemical molecule, or compound, that is used by cats and other felids for communication. These pheromones are produced and detected specifically by the body systems of cats and evoke certain behavioural responses. The name of the pheromone that calms a cat is Apaisins. Cat pheromones are commonly released through the action of scent rubbing. As such, one of the main proposed functions of pheromone release is to allow the cat to familiarize itself with its surroundings and other individuals, both in the newborn and adult stages of life. Specific cat pheromones that have been chemically identified include the feline facial pheromones F1-F5, the feline appeasing pheromone, and MMB in urine, most of which are associated with distinct feline behaviours. Some of these chemical makeups have been synthetically reproduced and may be used by cat owners or veterinary professionals looking to change problematic or stress-induced behaviours. Production and detection The ...
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Lactone
Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (), or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. Lactones are formed by intramolecular esterification of the corresponding hydroxycarboxylic acids, which takes place spontaneously when the ring that is formed is five- or six-membered. Lactones with three- or four-membered rings (α-lactones and β-lactones) are very reactive, making their isolation difficult. Special methods are normally required for the laboratory synthesis of small-ring lactones as well as those that contain rings larger than six-membered. Nomenclature Lactones are usually named according to the precursor acid molecule (''aceto'' = 2 carbon atoms, ''propio'' = 3, ''butyro'' = 4, ''valero'' = 5, ''capro'' = 6, etc.), with a ''-lactone'' suffix and a Greek letter prefix that specifies the number of carbon atoms in the heterocycle — that is, the distance between the relevant -OH ...
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Nepetalactol
Nepetalactol is an iridoid. It is produced from 8-oxogeranial by the enzyme iridoid synthase Iridoids are a type of monoterpenoids in the general form of cyclopentanopyran, found in a wide variety of plants and some animals. They are biosynthetically derived from 8-oxogeranial. Iridoids are typically found in plants as glycosides, mo .... Nepetalactol is a substrate for the enzyme iridoid oxidase (IO) which produces 7-deoxyloganetic acid. It has been identified in '' Actinidia polygama'' (the silver vine) as a major cat attractant, and a mosquito repellent. The fact that mosquitos bite cats with nepetalactol on their fur less often may explain why cats are attracted to silver vine in the first place. References {{Reflist Iridoids Cyclopentanes ...
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Refractive Index
In optics, the refractive index (or refraction index) of an optical medium is a dimensionless number that gives the indication of the light bending ability of that medium. The refractive index determines how much the path of light is bent, or refracted, when entering a material. This is described by Snell's law of refraction, , where ''θ''1 and ''θ''2 are the angle of incidence and angle of refraction, respectively, of a ray crossing the interface between two media with refractive indices ''n''1 and ''n''2. The refractive indices also determine the amount of light that is reflected when reaching the interface, as well as the critical angle for total internal reflection, their intensity (Fresnel's equations) and Brewster's angle. The refractive index can be seen as the factor by which the speed and the wavelength of the radiation are reduced with respect to their vacuum values: the speed of light in a medium is , and similarly the wavelength in that medium is , where ''Π...
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Lonicera Tatarica
''Lonicera tatarica'' is a species of honeysuckle known by the common name Tatarian honeysuckle. Native to Eurasia, the plant is one of several exotic bush honeysuckles present in North America, being considered an invasive species there. Description ''Lonicera tatarica'' is a bushy shrub which may approach in height. The twigs can be an array of colors from green to brown with a hollow brown pith. The plant is lined with oval or rounded simple leaves long. The leaves and stem range from long, wide. They are egg shaped and both hairless and toothless. The inflorescence ranges in color from deep rose to light pink, and can also be white. The petals are typically long, with a slender tube and 2 lips. The upper lip contains 4 lobes, the middle two erect and fused near the base. The white to pink to crimson red flowers are each about long, their stamens and styles protruding. The fruit is a shiny orange or red seed-containing berry up to 1'' ''cm wide. The berries are at ...
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Iridoid
Iridoids are a type of monoterpenoids in the general form of cyclopentanopyran, found in a wide variety of plants and some animals. They are biosynthetically derived from 8-oxogeranial. Iridoids are typically found in plants as glycosides, most often bound to glucose. The chemical structure is exemplified by iridomyrmecin, a defensive chemical produced by the ant genus '' Iridomyrmex'', for which iridoids are named. Structurally, they are bicyclic ''cis''-fused cyclopentane-pyrans. Cleavage of a bond in the cyclopentane ring gives rise to a subclass known as ''secoiridoids'', such as oleuropein and amarogentin. Occurrence The iridoids produced by plants act primarily as a defense against herbivores or against infection by microorganisms. The variable checkerspot butterfly also contains iridoids obtained through its diet which act as a defense against avian predators. To humans and other mammals, iridoids are often characterized by a deterrent bitter taste. Aucubin a ...
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