Neonatal Herpes
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Neonatal Herpes
Neonatal herpes simplex is a rare but serious condition, usually caused by vertical transmission of the herpes simplex virus from mother to newborn. Around 1 in every 3,500 babies in the United States contract the infection. Signs and Symptoms Neonatal herpes manifests itself in three forms: skin, eye, and mouth herpes (SEM, sometimes referred to as "localized"); disseminated herpes (DIS); and central nervous system herpes (CNS). * SEM herpes is characterized by external lesions but no internal organ involvement. Lesions are likely to appear on trauma sites such as the attachment site of fetal scalp electrodes, forceps, or vacuum extractors that are used during delivery; in the margin of the eyes; in the nasopharynx; and in areas associated with trauma or surgery (including circumcision). * DIS herpes affects internal organs, particularly the liver. * CNS herpes is an infection of the nervous system and the brain that can lead to encephalitis. Infants with CNS herpes present with s ...
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Vertical Transmission
Vertical transmission of symbionts is the transfer of a microbial symbiont from the parent directly to the offspring.  Many metazoan species carry symbiotic bacteria which play a mutualistic, commensal, or parasitic role.  A symbiont is acquired by a host via horizontal, vertical, or mixed transmission. Implications Complex interdependence occurs between host and symbiont. The genetic pool of the symbiont is generally smaller and more subject to genetic drift. In true vertical transmission, the evolutionary outcomes of the host and symbiont are linked. If there is mixed transmission, new genetic material may be introduced. Generally, symbionts settle into specific niches and can even transfer part of their genome into the host nucleus. Evolutionary consequences Benefits The mechanism promotes tightly coupled evolutionary pressure, which causes the host and symbiont to function as a holobiont. Disadvantages Evolutionary bottlenecks lead to less symbiont diversity, and ...
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Current Opinion In Infectious Diseases
''Current Opinion'' is a series of medical journals published by Wolters Kluwer imprint Lippincott Williams & Wilkins. Wolters Kluwer acquired the journals from the Thomson Organisation International Thomson Organization (ITO) was a holding company for interests in publishing, travel, and natural resources, that existed from 1978 to 1989. It was formed as a reorganisation of the Thomson Organization, which had been founded by Roy ... in 1997. Each of these journals publishes editorials and reviews within one of a number of medical disciplines. Journals The following journals are part of this series: References External links * {{DEFAULTSORT:Current Opinion (Lippincott Williams and Wilkins) Lippincott Williams & Wilkins academic journals Academic journal series ...
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Acyclovir
Aciclovir (ACV), also known as acyclovir, is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection. It can be taken by mouth, applied as a cream, or injected. Common side effects include nausea and diarrhea. Potentially serious side effects include kidney problems and low platelets. Greater care is recommended in those with poor liver or kidney function. It is generally considered safe for use in pregnancy with no harm having been observed. It appears to be safe during breastfeeding. Aciclovir is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA. Aciclovir was patented in 1974, and approved for medical use in 1981. It is on the World Health Organization's List of Essential Medicines. It is available as a generic me ...
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Vidarabine
Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Discovery In the 1950s two nucleosides were isolated from the Caribbean sea sponge, sponge ''Tethya crypta'': spongothymidine and spongouridine; which contained D-arabinose rather than D-ribose. These compounds led to the synthesis of a new generation, sugar modified nucleoside analog vidarabine, and the related compound cytarabine. In 2004 these were the only marine related compounds in clinical use. The drug was first synthesized in 1960 in the Bernard Randall Baker lab at the SRI International, Stanford Research Institute (now SRI International). The drug was originally intended as an anti-cancer drug. The anti-viral activity of vidarabine was first described by M. Privat de Garilhe and J. De Rudder in 1964. It was the first nucleoside analog antiviral drug, antiviral to be given systemically and was the first agent to be licensed f ...
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The Times Of Israel
''The Times of Israel'' is an Israeli multi-language online newspaper that was launched in 2012. It was co-founded by Israeli journalist David Horovitz, who is also the founding editor, and American billionaire investor Seth Klarman.Forbes: The World's Billionaires: Seth Klarman
April 2014
Based in , it "documents developments in Israel, the Middle East and around the ." Along with its original English site, ''The Times of Israel'' publishes in

Independent
Independent or Independents may refer to: Arts, entertainment, and media Artist groups * Independents (artist group), a group of modernist painters based in the New Hope, Pennsylvania, area of the United States during the early 1930s * Independents (Oporto artist group), a Portuguese artist group historically linked to abstract art and to Fernando Lanhas, the central figure of Portuguese abstractionism Music Groups, labels, and genres * Independent music, a number of genres associated with independent labels * Independent record label, a record label not associated with a major label * Independent Albums, American albums chart Albums * ''Independent'' (Ai album), 2012 * ''Independent'' (Faze album), 2006 * ''Independent'' (Sacred Reich album), 1993 Songs * "Independent" (song), a 2007 song by Webbie * "Independent", a 2002 song by Ayumi Hamasaki from '' H'' News and media organizations * ''The Independent'', a British online newspaper. * ''The Malta Independent'', a Mal ...
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ABC News
ABC News is the news division of the American broadcast network ABC. Its flagship program is the daily evening newscast ''ABC World News Tonight, ABC World News Tonight with David Muir''; other programs include Breakfast television, morning news-talk show ''Good Morning America'', ''Nightline'', ''Primetime (American TV program), Primetime'', and ''20/20 (American TV program), 20/20'', and Sunday morning talk shows, Sunday morning political affairs program ''This Week (ABC TV series), This Week with George Stephanopoulos''. In addition to the division's television programs, ABC News has radio and digital outlets, including ABC News Radio and ABC News Live, plus various podcasts hosted by ABC News personalities. History Early years ABC began in 1943 as the Blue Network, NBC Blue Network, a radio network that was Corporate spin-off, spun off from NBC, as ordered by the Federal Communications Commission (FCC) in 1942. The reason for the order was to expand competition in radi ...
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Prophylactic
Preventive healthcare, or prophylaxis, consists of measures taken for the purposes of disease prevention.Hugh R. Leavell and E. Gurney Clark as "the science and art of preventing disease, prolonging life, and promoting physical and mental health and efficiency. Leavell, H. R., & Clark, E. G. (1979). Preventive Medicine for the Doctor in his Community (3rd ed.). Huntington, NY: Robert E. Krieger Publishing Company. Disease and disability are affected by environmental factors, genetic predisposition, disease agents, and lifestyle choices, and are dynamic processes which begin before individuals realize they are affected. Disease prevention relies on anticipatory actions that can be categorized as primal, primary, secondary, and tertiary prevention. Each year, millions of people die of preventable deaths. A 2004 study showed that about half of all deaths in the United States in 2000 were due to preventable behaviors and exposures. Leading causes included cardiovascular disease ...
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Oral Suction
The ''brit milah'' ( he, בְּרִית מִילָה ''bərīṯ mīlā'', ; Ashkenazi Hebrew, Ashkenazi pronunciation: , "Covenant (religion), covenant of circumcision"; Yiddish pronunciation: ''bris'' ) is Religion and circumcision, the ceremony of circumcision in Judaism. According to the Book of Genesis, God in Judaism, God commanded the Patriarchs (Bible), biblical patriarch Abraham to be circumcised, an act to be followed by his male descendants on the eighth day of life, symbolizing Covenant of the pieces, the covenant between God and the Jewish people. Today, it is generally performed by a mohel on the eighth day after the infant's birth and is followed by a celebratory meal known as ''seudat mitzvah''. ''Brit Milah'' is considered among the 613 commandments, most important and central commandments in Judaism, and the rite has played a central role in Jewish history, the formation and history of Jewish culture, Jewish civilization. The Talmud, when discussing the importa ...
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Herpetic Gingivostomatitis
Gingivostomatitis is a combination of gingivitis and stomatitis, or an inflammation of the oral mucosa and gingiva. Herpetic gingivostomatitis is often the initial presentation during the first ("primary") herpes simplex infection. It is of greater severity than herpes labialis (cold sores) which is often the subsequent presentations. Primary herpetic gingivostomatitis is the most common viral infection of the mouth. Primary herpetic gingivostomatitis (PHGS) represents the clinically apparent pattern of primary herpes simplex virus (HSV) infection, since the vast majority of other primary infections are symptomless. PHGS is caused predominantly by HSV-1 and affects mainly children. Prodromal symptoms, such as fever, anorexia, irritability, malaise and headache, may occur in advance of disease. The disease presents as numerous pin-head vesicles, which rupture rapidly to form painful irregular ulcerations covered by yellow–grey membranes. Sub-mandibular lymphadenitis, halitosis and ...
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Mohel
A ( he, מוֹהֵל , Ashkenazi pronunciation , plural: , arc, מוֹהֲלָא , "circumciser") is a Jew trained in the practice of , the "covenant of circumcision". Etymology The noun ( in Aramaic), meaning "circumciser", is derived from the same verb stem as (circumcision). The noun appeared for the first time in the 4th century as the title of a circumciser (Shabbat (Talmud) 156a). Origins of circumcision in Judaism For Jews, male circumcision is mandatory as it is prescribed in the Torah. In the Book of Genesis, it is described as a mark of the covenant of the pieces between Yahweh and the descendants of Abraham: In Leviticus: Functions Biblically, the infant's father () is commanded to perform the circumcision himself. However, as most fathers are not comfortable or do not have the training, they designate a . The is specially trained in circumcision and the rituals surrounding the procedure. Many are doctors or rabbis (and some are both) or cantors and are ...
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Postnatal
The postpartum (or postnatal) period begins after childbirth and is typically considered to end within 6 weeks as the mother's body, including hormone levels and uterus size, returns to a non-pregnant state. The terms puerperium, puerperal period, or immediate postpartum period are commonly used to refer to the first six weeks following childbirth. The World Health Organization (WHO) describes the postnatal period as the most critical and yet the most neglected phase in the lives of mothers and babies; most maternal and infant mortality, newborn deaths occur during this period. In scientific literature, the term is commonly abbreviated to P''x'', where ''x'' is a number; for example, "day P5" should be read as "the fifth day after birth". This is not to be confused with the medical nomenclature that uses G P to stand for number and outcomes of pregnancy (gravidity and parity). A female giving birth in a hospital may leave as soon as they are medically stable, which can be as ea ...
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