Nanopipette
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Nanopipette
Nanopipettes are pipettes in nanometer 330px, Different lengths as in respect to the molecular scale. The nanometre (international spelling as used by the International Bureau of Weights and Measures; SI symbol: nm) or nanometer (American and British English spelling differences#-re ... scale, generally made from quartz capillaries with the help of laser-based pipette puller system. Glass and carbon nanopipettes are most encountered ones in literature. Carbon nanopipettes are nanopipette shaped, hollow carbon layer. The thickness or diameter of nanopipettes can be altered. Glass nanopipettes have a wide range of usage areas like electrophysiological settings, microinjection needles etc. After glass nanopipettes are fabricated and coated with carbon layer in different ways, wet-etching method is applied to get carbon nanopipettes.M. Schrlau, E. Falls, B. Ziober and H. Bau, Nanotechnology, 2008, 19, 0151101 Wet-etching method is done to get rid of glass nanopipettes. Nanopipet ...
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Pipettes
A pipette (sometimes spelled as pipett) is a laboratory tool commonly used in chemistry, biology and medicine to transport a measured volume of liquid, often as a media dispenser. Pipettes come in several designs for various purposes with differing levels of accuracy and precision, from single piece glass pipettes to more complex adjustable or electronic pipettes. Many pipette types work by creating a partial vacuum above the liquid-holding chamber and selectively releasing this vacuum to draw up and dispense liquid. Measurement accuracy varies greatly depending on the instrument. History The first simple pipettes were made in glass, such as Pasteur pipettes. Large pipettes continue to be made in glass; others are made in squeezable plastic for situations where an exact volume is not required. The first micropipette was patented in 1957 by Dr Heinrich Schnitger (Marburg, Germany). The founder of the company Eppendorf, Dr. Heinrich Netheler, inherited the rights and started the ...
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Nanometer
330px, Different lengths as in respect to the molecular scale. The nanometre (international spelling as used by the International Bureau of Weights and Measures; SI symbol: nm) or nanometer (American and British English spelling differences#-re, -er, American spelling) is a units of measurement, unit of length in the International System of Units (SI), equal to one billionth (short scale) of a metre () and to 1000 picometres. One nanometre can be expressed in scientific notation as , and as  metres. History The nanometre was formerly known as the millimicrometre – or, more commonly, the millimicron for short – since it is of a micron (micrometre), and was often denoted by the symbol mμ or (more rarely and confusingly, since it logically should refer to a ''millionth'' of a micron) as μμ. Etymology The name combines the SI prefix ''nano-'' (from the Ancient Greek , ', "dwarf") with the parent unit name ''metre'' (from Greek , ', "unit of measurement"). ...
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Quartz
Quartz is a hard, crystalline mineral composed of silica (silicon dioxide). The atoms are linked in a continuous framework of SiO4 silicon-oxygen tetrahedra, with each oxygen being shared between two tetrahedra, giving an overall chemical formula of SiO2. Quartz is the second most abundant mineral in Earth's continental crust, behind feldspar. Quartz exists in two forms, the normal α-quartz and the high-temperature β-quartz, both of which are chiral. The transformation from α-quartz to β-quartz takes place abruptly at . Since the transformation is accompanied by a significant change in volume, it can easily induce microfracturing of ceramics or rocks passing through this temperature threshold. There are many different varieties of quartz, several of which are classified as gemstones. Since antiquity, varieties of quartz have been the most commonly used minerals in the making of jewelry and hardstone carvings, especially in Eurasia. Quartz is the mineral defining the val ...
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Capillaries
A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. These microvessels are the site of exchange of many substances with the interstitial fluid surrounding them. Substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in the microcirculation. During early embryonic development, new capillaries are formed through vasculogenesis, the process of blood vessel formation that occurs through a '' de novo'' production of endothelial cells that then form vascular tubes. The term ''angiogenesis'' denotes the formation of new capillaries from pre-existing blood vessels and already present endo ...
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Puller System
Puller may refer to: Fish * Several species in the genus '' Chromis'' * One-spot puller or brown puller, ''Atypichthys latus'' * Reticulated puller, ''Dascyllus reticulatus'' * Spiny-tail puller, ''Acanthochromis polyacanthus'' * White-spot puller, ''Dascyllus trimaculatus'' Tools * Bearing puller * Nail puller * Wire puller or wire stretcher * Puller (dog sport tool) People * Richard Puller (1747–1826), English merchant banker * Sir Christopher Puller (1774 – 26 May 1824), English lawyer; briefly Chief Justice of Bengal; son of Richard * Chesty Puller, a United States Marine Corps officer during World War II and the Korean War, and the most decorated Marine in the history of the Corps * Lewis Puller, son of Chesty Puller, who was maimed during the Vietnam War and took his own life due to complications from his injuries two and a half decades later Other * Puller (computer gaming), a character in an MMORPG whose primary task in a party is to get the initial atten ...
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Carbon
Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent In chemistry, the valence (US spelling) or valency (British spelling) of an element is the measure of its combining capacity with other atoms when it forms chemical compounds or molecules. Description The combining capacity, or affinity of an ...—its atom making four electrons available to form covalent bond, covalent chemical bonds. It belongs to group 14 of the periodic table. Carbon makes up only about 0.025 percent of Earth's crust. Three Isotopes of carbon, isotopes occur naturally, Carbon-12, C and Carbon-13, C being stable, while Carbon-14, C is a radionuclide, decaying with a half-life of about 5,730 years. Carbon is one of the Timeline of chemical element discoveries#Ancient discoveries, few elements known since antiquity. Carbon is the 15th Abundance of elements in Earth's crust, most abundant element in the Earth's crust, and the Abundance of the c ...
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Nanophysiology
Nanophysiology is a field that concerns the function of nanodomains, such as the regulation of molecular or ionic flows in cell subcompartments, such as glial protrusions, dendritic spines, dendrites, mitochondria and many more. Background Molecular organization in nanocompartments provides the construction required to achieve elementary functions that can sustain higher physiological functions of a cell. This includes calcium homeostatis, protein turn over, plastic changes underlying cell communications. The goal of this field is to determine the function of these nanocompartments based on molecular organization, ionic flow or voltage distribution. Voltage dynamics How the voltage is regulated in nanodomains remains an open field. While the classical Goldman-Hodgkin-Huxley-Katz models in biophysics provides a foundation for electrophysiology and has been responsible for many advances in neuroscience, this theory remains insufficient to describe the voltage dynamics in ...
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