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Myxoid Chondrosarcoma
Myxoid chondrosarcoma is a type of chondrosarcoma. It has been associated with a t(9;22) (q22;q12) EWS/ CHN gene fusion. References External links Osseous and chondromatous neoplasia {{oncology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chondrosarcoma
Chondrosarcoma is a bone sarcoma, a primary cancer composed of cells derived from transformed cells that produce cartilage. A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. About 30% of bone sarcomas are chondrosarcomas. It is resistant to chemotherapy and radiotherapy. Unlike other primary bone sarcomas that mainly affect children and adolescents, a chondrosarcoma can present at any age. It more often affects the axial skeleton than the appendicular skeleton. Types Symptoms and signs * Back or thigh pain * Sciatica * Bladder Symptoms * Unilateral edema Causes The cause is unknown. There may be a history of enchondroma or osteochondroma. A small minority of secondary chondrosarcomas occur in people with Maffucci syndrome and Ollier disease. It has been associated with faulty isocitrate dehydrogenase 1 and 2 enzymes, which are also associated with gliomas and leukemias. Diagnosis Imaging studies – including radiographs ("x-ray ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ewing Sarcoma Breakpoint Region 1
RNA-binding protein EWS is a protein that in humans is encoded by the ''EWSR1'' gene on human chromosome 22, specifically 22q12.2. It is one of 3 proteins in the FET protein family. The q22.2 region of chromosome 22 encodes the N-terminal transactivation domain of the EWS protein and that region may become joined to one of several other chromosomes which encode various transcription factors, see and the FET protein family. The expression of a chimeric protein with the EWS transactivation domain fused to the DNA binding region of a transcription factor generates a powerful oncogenic protein causing Ewing sarcoma and other members of the Ewing family of tumors. These translocations can occur due to chromoplexy, a burst of complex chromosomal rearrangements seen in cancer cells. The normal EWS gene encodes an RNA binding protein closely related to FUS (gene) and TAF15, all of which have been associated to amyotrophic lateral sclerosis. Interactions The EWS protein has been shown to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CHN (gene)
CHN may stand for: * China's country code ** People's Republic of China's ISO 3166-1 alpha-3 and IOC country code ** Republic of China's IOC country code 1932–1956, now TPE * Canadian Health Network * Cheshunt railway station, Hertfordshire, National Rail station code * CHN analyzer, measuring carbon, hydrogen, and nitrogen * City Hindus Network, London, UK * Anglican religious orders ** Community of the Holy Name, an Anglican religious order for women in England, Lesotho and South Africa ** Community of the Holy Name (Australia), an Anglican religious order for women in Australia, unrelated to the English order * Jeonju Airport, South Korea, IATA airport code * Chennai, a megacity in South India. * Chemical formula of hydrogen cyanide and hydrogen isocyanide * Climate Heritage Network The Climate Heritage Network (CHN) was set up in 2018 and launched in 2019 in response to the Global Climate Action Summit and the impacts of climate change on the arts, culture and heritage se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
