Mossy Fiber (other)
Mossy fiber may refer to two different bundles of axons in the brain: * Mossy fiber (cerebellum) Mossy fibers are one of the major inputs to cerebellum. There are many sources of this pathway, the largest of which is the cerebral cortex, which sends input to the cerebellum via the pontocerebellar pathway. Other contributors include the ve ... * Mossy fiber (hippocampus) {{Disambig ...
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Mossy Fiber (cerebellum)
Mossy fibers are one of the major inputs to cerebellum. There are many sources of this pathway, the largest of which is the cerebral cortex, which sends input to the cerebellum via the pontocerebellar pathway. Other contributors include the vestibular nerve and nuclei, the spinal cord, the reticular formation, and feedback from deep cerebellar nuclei. Axons enter the cerebellum via the middle and inferior cerebellar peduncles, where some branch to make contact with deep cerebellar nuclei. They ascend into the white matter of the cerebellum, where each axon branches to innervate granule cells in several cerebellar folia. In this case, the pathway is so named for a unique synapse formed by its projections, the ''mossy fiber rosette''. Fine branches of the mossy fiber axons twist through the granule cell layer, and slight enlargements giving a knotted appearance indicate synaptic contacts. These contacts have the appearance of a classic Gray's type 1 synapse, indicating they are ...
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