MiR-138
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MiR-138
miR-138 is a family of microRNA precursors found in animals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-138 precursor is the microRNA mir-138. miR-138 has been used as an example of the post-transcriptional regulation of miRNA, due to the finding that while the precursor is expressed ubiquitously, the mature product is found only in specific cell types. Species distribution The presence of miR-138 has been detected experimentally in humans (''Homo sapiens'') and in different animals including house mouse (''Mus musculus''), brown rat (''Rattus norvegicus''), platypus (''Ornithorhynchus anatinus''), Carolina anole(''Anolis carolinensis''), cattle (''Bos taurus''), common carp (''Cyprinus carpio''), dog (''Canis familiaris''), Chinese hamster (''Cricetulus griseus''), zebrafish (''Danio rerio''), red junglefowl ...
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MicroRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in mRNA molecules, then gene silence said mRNA molecules by one or more of the following processes: (1) cleavage of mRNA strand into two pieces, (2) destabilization of mRNA by shortening its poly(A) tail, or (3) translation of mRNA into proteins. This last method of gene silencing is the least efficient of the three, and requires the aid of ribosomes. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1900 miRNAs, although more recent analysis suggests that ...
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Animalia
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echinode ...
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Pongo Pygmaeus
The Bornean orangutan (''Pongo pygmaeus'') is a species of orangutan endemic to the island of Borneo. Together with the Sumatran orangutan (''Pongo abelii'') and Tapanuli orangutan (''Pongo tapanuliensis''), it belongs to the only genus of great apes native to Asia. Like the other great apes, orangutans are highly intelligent, displaying tool use and distinct cultural patterns in the wild. Orangutans share approximately 97% of their DNA with humans. Also called mias by the local population, the Bornean orangutan is a critically endangered species, with deforestation, palm oil plantations, and hunting posing a serious threat to its continued existence. Taxonomy The Bornean orangutan and the Sumatran orangutan diverged about 400,000 years ago, with a continued low level of gene flow between them since then. The two orangutan species were considered merely subspecies until 1996; they were elevated to species following sequencing of their mitochondrial DNA. The Bornean orangu ...
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Bornean Orangutan
The Bornean orangutan (''Pongo pygmaeus'') is a species of orangutan endemic to the island of Borneo. Together with the Sumatran orangutan (''Pongo abelii'') and Tapanuli orangutan (''Pongo tapanuliensis''), it belongs to the only genus of great apes native to Asia. Like the other great apes, orangutans are highly intelligent, displaying tool use and distinct cultural patterns in the wild. Orangutans share approximately 97% of their DNA with humans. Also called mias by the local population, the Bornean orangutan is a critically endangered species, with deforestation, palm oil plantations, and hunting posing a serious threat to its continued existence. Taxonomy The Bornean orangutan and the Sumatran orangutan diverged about 400,000 years ago, with a continued low level of gene flow between them since then. The two orangutan species were considered merely subspecies until 1996; they were elevated to species following sequencing of their mitochondrial DNA. The Bornean orangutan ...
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Takifugu Rubripes
''Takifugu rubripes'', commonly known as the Japanese puffer, Tiger puffer, or torafugu ( ja, 虎河豚), is a pufferfish in the genus ''Takifugu''. It is distinguished by a very small genome that has been fully sequenced because of its use as a model species and is in widespread use as a reference in genomics. Taxonomy and etymology The species is often referred to in the genomics literature as ''Fugu rubripes''. The genus ''Fugu'' is a synonym of the currently preferred ''Takifugu''. ''Takifugu'' is Japanese for puffer and ''rubripes'' comes from the Latin ''ruber'' and ''pēs'' meaning ruddy foot. Distribution and habitat The species is known from the Sea of Japan, East China Sea and Yellow Sea north to southern Sakhalin, at depths of . It is a demersal species. Spawning occurs in estuaries; young fish can tolerate a wide range of salinities and will remain in river mouths and lagoons, maturing for one year before migrating permanently to the open ocean. Genome A feature of th ...
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Rhesus Macaque
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ...
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Horse
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from anatomy to life stages, size, colors, markings, breeds, locomotion, and behavior. Horses are adapted to run, allowing them to quickly escape predators, and po ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Zebra Finch
The zebra finches are two species of estrildid finch in the genus ''Taeniopygia'' found in Australia and Indonesia. They are seed-eaters that travel in large flocks. The species are: Previously, both species were classified as a single species, the zebra finch (''T. guttata''). However, they were split by the IUCN Red List and BirdLife International in 2016. The International Ornithological Congress followed suit in 2022 based on studies noting differences in plumage, mtDNA divergence, and assortative mating between both species in captivity. The zebra finch was first captured in 1801 during Nicolas Baudin's expedition to Australia. The Indonesian species was described in 1817 by Louis Jean Pierre Vieillot in his ''Nouveau Dictionnaire d'Histoire Naturelle'', where he gave it the scientific name ''Fringilla guttata''. The Australian species was then described in 1837 by John Gould as ''Amadina castanotis''. Its current genus, ''Taeniopygia'', was described in 1862 by Ludwig R ...
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Wild Boar
The wild boar (''Sus scrofa''), also known as the wild swine, common wild pig, Eurasian wild pig, or simply wild pig, is a suid native to much of Eurasia and North Africa, and has been introduced to the Americas and Oceania. The species is now one of the widest-ranging mammals in the world, as well as the most widespread suiform. It has been assessed as least concern on the IUCN Red List due to its wide range, high numbers, and adaptability to a diversity of habitats. It has become an invasive species in part of its introduced range. Wild boars probably originated in Southeast Asia during the Early Pleistocene and outcompeted other suid species as they spread throughout the Old World. , up to 16 subspecies are recognized, which are divided into four regional groupings based on skull height and lacrimal bone length. The species lives in matriarchal societies consisting of interrelated females and their young (both male and female). Fully grown males are usually solitary ...
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Tasmanian Devil
The Tasmanian devil (''Sarcophilus harrisii'') (palawa kani: purinina) is a carnivorous marsupial of the family Dasyuridae. Until recently, it was only found on the island state of Tasmania, but it has been reintroduced to New South Wales in mainland Australia, with a small breeding population. The size of a small dog, the Tasmanian devil became the largest carnivorous marsupial in the world following the extinction of the thylacine in 1936. It is related to quolls, and distantly related to the thylacine. It is characterised by its stocky and muscular build, black fur, pungent odour, extremely loud and disturbing screech, keen sense of smell, and ferocity when feeding. The Tasmanian devil's large head and neck allow it to generate among the strongest bites per unit body mass of any extant predatory land mammal. It hunts prey and scavenges on carrion. Although devils are usually solitary, they sometimes eat and defecate together in a communal location. Unlike most other da ...
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Sea Lamprey
The sea lamprey (''Petromyzon marinus'') is a parasitic lamprey native to the Northern Hemisphere. It is sometimes referred to as the "vampire fish". Description The sea lamprey has an eel-like body without paired fins. Its mouth is jawless, round and sucker-like, and as wide or wider than the head; sharp teeth are arranged in many concentric circular rows. There are seven branchial or gill-like openings behind the eye. Sea lampreys are olive or brown-yellow on the dorsal and lateral part of the body, with some black marblings, with lighter coloration on the belly. Adults can reach a length of up to and a body weight up to . Etymology The etymology of the genus name ''Petromyzon'' is from '' petro-'' "stone" and '' myzon'' "sucking"; ''marinus'' is Latin for "of the sea". Distribution and habitat The species is found in the northern and western Atlantic Ocean along the shores of Europe and North America, in the western Mediterranean Sea, the Black Sea, and as an invasive speci ...
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