Methylcytosine
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Methylcytosine
Methylcytosine may refer to: * 5-Methylcytosine * 1-Methylcytosine, a nucleic acid in Hachimoji DNA * N(4)-Methylcytosine * 6-Methylcytosine See also * Cytosine * Nucleic acid analogue Nucleic acid analogues are compounds which are Analog (chemistry), analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research. Nucleic acids are chains of nucleotides, which are compos ... {{Short pages monitor ...
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Cytosine
Cytosine () ( symbol C or Cyt) is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. History Cytosine was discovered and named by Albrecht Kossel and Albert Neumann in 1894 when it was hydrolyzed from calf thymus tissues. A structure was proposed in 1903, and was synthesized (and thus confirmed) in the laboratory in the same year. In 1998, cytosine was used in an early demonstration of quantum information processing when Oxford University researchers implemented the Deutsch-Jozsa algorithm on a two qubit nuclear magnetic resonance quantum computer (NMRQC). In March 2015, NASA scientists reported the formation of cytosine, along with uracil and thym ...
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1-Methylcytosine
1-Methylcytosine is a methylated form of the DNA base cytosine. In 1-methylcytosine, a methyl group is attached to the 1st atom in the 6-atom ring. This methyl group distinguishes 1-methylcytosine from cytosine. History Miriam Rossi worked on the refinement of 1-methylcytosine. 1-Methylcytosine is used as a nucleobase of hachimoji DNA, in which it pairs with isoguanine Isoguanine or 2-hydroxyadenine is a purine base that is an isomer of guanine. It is a product of oxidative damage to DNA and has been shown to cause mutation. It is also used in combination with isocytosine in studies of unnatural nucleic acid a .... References {{DEFAULTSORT:Methylcytosine1 Nucleobases Pyrimidones ...
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N(4)-Methylcytosine
N, or n, is the fourteenth letter in the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is ''en'' (pronounced ), plural ''ens''. History One of the most common hieroglyphs, snake, was used in Egyptian writing to stand for a sound like the English , because the Egyptian word for "snake" was ''djet''. It is speculated by many that Semitic people working in Egypt adapted hieroglyphics to create the first alphabet, and that they used the same snake symbol to represent N, because their word for "snake" may have begun with that sound. However, the name for the letter in the Phoenician, Hebrew, Aramaic and Arabic alphabets is '' nun'', which means " fish" in some of these languages. The sound value of the letter was —as in Greek, Etruscan, Latin and modern languages. Use in writing systems represents a dental or alveolar nasal in virtually all languages that u ...
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