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Membrana Granulosa
The larger ovarian follicles An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle. At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with t ... consist of an external fibrovascular coat, connected with the surrounding stroma of the ovary by a network of blood vessels, and an internal coat, which consists of several layers of nucleated cells, called the membrana granulosa. It contains numerous granulosa cells. At one part of the mature follicle the cells of the membrana granulosa are collected into a mass which projects into the cavity of the follicle. This is termed the discus proligerus. References External links * - "Female Reproductive System: ovary, cumulus oophorus" * - "Female Reproductive System: ovary, membrana granulosa" * Description at okstate.edu Mammal female reproductive system {{Portal bar, Anatomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovarian Follicles
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle. At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with the potential to release an egg cell (ovum) at ovulation for fertilization. These eggs are developed once every menstrual cycle with around 450–500 being ovulated during a woman's reproductive lifetime. Structure Ovarian follicles are the basic units of female reproductive biology. Each of them contains a single oocyte (immature ovum or egg cell). These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. They also consist of granulosa cells and theca of follicle. Oocyte Once a month, one of the ovaries releases a mature egg (ovum), known as an oocyte. The nucleus of such an oocyte is called a '' germinal vesicle (see picture).'' Cumulus oophorus Cumulus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stroma Of The Ovary
The stroma of the ovary is a unique type of connective tissue abundantly supplied with blood vessels, consisting for the most part of spindle-shaped stroma cells. These appear similar to fibroblasts. The stroma also contains ordinary connective tissue such as reticular fibers and collagen. Ovarian stroma differs from typical connective tissue in that it contains a high number of cells. The stoma cells are distributed in such a way that the tissue appears to be whorled. Stromal cells associated with maturing follicles may acquire endocrine function and secrete estrogens. The entire ovarian stroma is highly vascular. On the surface of the organ this tissue is much condensed, and forms a layer ( tunica albuginea) composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. See also * stroma (other) * Stromal cell Stromal cells, or mesenchymal stromal cells, are diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Granulosa Cells
A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called an oocyte or egg) in the ovary of mammals. Structure and function In the primordial ovarian follicle, and later in follicle development (folliculogenesis), granulosa cells advance to form a multilayered cumulus oophorus surrounding the oocyte in the preovulatory or antral (or Graafian) follicle. The major functions of granulosa cells include the production of sex steroids, as well as myriad growth factors thought to interact with the oocyte during its development. The sex steroid production begins with follicle-stimulating hormone (FSH) from the anterior pituitary, stimulating granulosa cells to convert androgens (coming from the thecal cells) to estradiol by aromatase during the follicular phase of the menstrual cycle. However, after ovulation the granulosa cells turn into granulosa lutein cells that produce progesterone. The progesterone may ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Discus Proligerus
The cumulus oophorus, (discus proligerus), is a cluster of cells that surround the oocyte both in the ovarian follicle and after ovulation. In the antral follicle, it may be regarded as an extension of the membrana granulosa. The innermost layer of these cells is the corona radiata. This layer of cells must be penetrated by spermatozoa for fertilization to occur. Functions Functions of the cumulus oophorus include coordination of follicular development and oocyte maturation. Mechanisms of the latter include stimulation of amino acid transport and sterol biosynthesis and regulation of oocyte gene transcription. It also provides energy substrates for oocyte meiotic resumption and promotes glycolysis. Cumulus oophorus cells contribute heavily to the maturation and eventual fertilization of an oocyte. As a follicle grows in size and the antrum develops, more layers of cumulus oophorus cells accumulate around the oocyte to aid in the acrosome reaction and sperm penetration into t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
