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Momordin (saponin)
Momordin is one of several saponins derived from oleanolic acid, a triterpenoid. These chemical compounds are found in some plants of the genus ''Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''), as well as in other Asian herbal medicine plants such as ''Kochia scoparia'' and ''Ampelopsis radix''. Momordins include: * Momordin I, oleanolic acid 3-''O''-α-''L''-arabinopyranosyl(1→3)-β-D-glucuronopyranoside. A white powder that decomposes at 235–240 °C. Found in the root of ''Momordica cochinchinensis'' where it constitutes 10% of the dried methanol extract. * Momordin Ia, from ''M. cochinchinensis''. * Momordin Ib, from ''M. cochinchinensis''. * Momordin Ic or (3β)-17-carboxy-28-norolean-12-en-3-yl 3'-''O''-(β-D-xylopyranosyl)-β-D-glucuronide (), CAS number 96990-18-0. It is obtained as colorless fine crystals that decompose at 240 °C. It inhibits gastric emptying in mice. * Momordin Id, from ''M. cochinchi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saponin
Saponins (Latin "sapon", soap + "-in", one of), also selectively referred to as triterpene glycosides, are bitter-tasting usually toxic plant-derived organic chemicals that have a foamy quality when agitated in water. They are widely distributed but found particularly in soapwort (genus Saponaria), a flowering plant, the soapbark tree (''Quillaja saponaria'') and soybeans (''Glycine max'' L.). They are used in soaps, medicinals, fire extinguishers, speciously as dietary supplements, for synthesis of steroids, and in carbonated beverages (the head on a mug of root beer). Structurally, they are glycosides, sugars bonded to another organic molecule, usually a steroid or triterpene, a steroid building block. Saponins are both water and fat soluble, which gives them their useful soap properties. Some examples of these chemicals are glycyrrhizin, licorice flavoring; and quillaia (alt. quillaja), a bark extract used in beverages. Uses The saponins are a subclass of terpenoids, the larges ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin Ie
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin) Momordin is one of several saponins derived from oleanolic acid, a triterpenoid. These chemical compounds are found in some plants of the genus ''Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina'') ..., a derivative of the triterpenoid oleanic acid * Momordin (protein), an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin (protein)
Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibitor of protein synthesis in eukaryotes by inactivating the ribosomes. However its cytotoxic activity is limited because it is not taken up by the cells; it has to be chemically modified to do so. There are several variants, including momordin II (from ''M. balsamina'') and momordin-a (from ''M. charantia''). See also * Momordin (saponin), an unrelated compound (a saponin of the triterpenoid Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squale ... oleanic acid). References Ribosome-inactivating proteins {{protein-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin III
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin IIe
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin IId
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleanic Acid
Oleanolic acid or oleanic acid is a naturally occurring pentacyclic triterpenoid related to betulinic acid. It is widely distributed in food and plants where it exists as a free acid or as an aglycone of triterpenoid saponins. Natural occurrence Oleanolic acid can be found in olive oil, '' Phytolacca americana'' (American pokeweed), and '' Syzygium'' spp, garlic, etc. It was first studied and isolated from several plants, including ''Olea europaea'' (leaves, fruit), ''Rosa woodsii'' (leaves), '' Prosopis glandulosa'' (leaves and twigs), ''Phoradendron juniperinum'' (whole plant), '' Syzygium claviflorum'' (leaves), ''Hyptis capitata'' (whole plant), '' Mirabilis jalapa'') and ''Ternstroemia gymnanthera'' (aerial part). Other ''Syzygium'' species including java apple ('' Syzygium samarangense'') and rose apples contain it, as does ''Ocimum tenuiflorum'' (holy basil). Biosynthesis of oleanolic acids Oleanolic acid biosynthesis starts with mevalonate to create squalene. Squal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin IIc
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin IIb
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin IIa
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemsleya Chinensis
''Hemsleya'' is a genus of flowering plants belonging to the family Cucurbitaceae. Its native range is Eastern Himalayas to southern China and Papuasia. It is native to the countries of Assam (in India), Bismarck Archipelago (island group, part of Papua New Guinea), China, East Himalayas, Maluku Islands, New Guinea, Thailand and Vietnam. The genus name of ''Hemsleya'' is in honour of William Hemsley (1843–1924), an English botanist. It was first described and published in J. Linn. Soc., Bot. Vol.23 on page 490 in 1888. Knowns species According to Kew: *'' Hemsleya amabilis'' *''Hemsleya carnosiflora'' *'' Hemsleya chengyihana'' *'' Hemsleya chinensis'' *''Hemsleya cirromitrata'' *'' Hemsleya delavayi'' *''Hemsleya dipteriga'' *'' Hemsleya dolichocarpa'' *'' Hemsleya dulongjiangensis'' *'' Hemsleya ellipsoidea'' *'' Hemsleya emeiensis'' *'' Hemsleya endecaphylla'' *'' Hemsleya gigantha'' *'' Hemsleya graciliflora'' *'' Hemsleya kunmingensis'' *'' Hemsl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemsleya Macrosperma
''Hemsleya'' is a genus of flowering plants belonging to the family Cucurbitaceae. Its native range is Eastern Himalayas to southern China and Papuasia. It is native to the countries of Assam (in India), Bismarck Archipelago (island group, part of Papua New Guinea), China, East Himalayas, Maluku Islands, New Guinea, Thailand and Vietnam. The genus name of ''Hemsleya'' is in honour of William Hemsley (1843–1924), an English botanist. It was first described and published in J. Linn. Soc., Bot. Vol.23 on page 490 in 1888. Knowns species According to Kew: *'' Hemsleya amabilis'' *''Hemsleya carnosiflora'' *'' Hemsleya chengyihana'' *'' Hemsleya chinensis'' *''Hemsleya cirromitrata'' *'' Hemsleya delavayi'' *''Hemsleya dipteriga'' *''Hemsleya dolichocarpa'' *'' Hemsleya dulongjiangensis'' *'' Hemsleya ellipsoidea'' *'' Hemsleya emeiensis'' *''Hemsleya endecaphylla'' *''Hemsleya gigantha'' *''Hemsleya graciliflora'' *''Hemsleya kunmingensis'' *''Hemsleya lijiangen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
