Methyltryptamine
Methyltryptamine may refer to: * ''N''-Methyltryptamine * α-Methyltryptamine {{Short pages monitor ...
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N-Methyltryptamine
''N''-Methyltryptamine (NMT) is a member of the substituted tryptamine chemical class and a natural product which is biosynthesized in the human body from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine ''N''-methyltransferase. It is a common component in human urine. NMT is an alkaloid derived from L-tryptophan that has been found in the bark, shoots and leaves of several plant genera, including ''Virola'', ''Acacia'', ''Mimosa'', and ''Desmanthus''—often together with the related compounds ''N'',''N''-dimethyltryptamine (DMT) and 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT). Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism.Foye's principles of medicinal chemistry By William O. Foye, Thomas L. Lemke, David A. Williams However, it may become active upon combination with a MAOA inhibitor (MAOI). By vaporization NMT shows activity at 50–100 mg, with a duration o ...
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