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Mandibular Arch
The pharyngeal arches, also known as visceral arches'','' are transient structures seen in the embryonic development of humans and other vertebrates, that are recognisable precursors for many structures. In fish, the arches support the gills and are known as the branchial arches, or gill arches. In the human embryo, the arches are first seen during the fourth week of development. They appear as a series of outpouchings of mesoderm on both sides of the developing pharynx. The vasculature of the pharyngeal arches are the aortic arches that arise from the aortic sac. Structure In humans and other vertebrates, the pharyngeal arches are derived from all three germ layers (the primary layers of cells that form during embryonic development). Neural crest cells enter these arches where they contribute to features of the skull and facial skeleton such as bone and cartilage. However, the existence of pharyngeal structures before neural crest cells evolved is indicated by the existence of ...
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Pharyngeal Pouch (embryology)
In the embryonic development of vertebrates, pharyngeal pouches form on the endodermal side between the pharyngeal arches. The pharyngeal grooves (or clefts) form the lateral ectodermal surface of the neck region to separate the arches. Specific pouches First pouch The endoderm lines the future auditory tube (pharyngotympanic Eustachian tube), middle ear, mastoid antrum, and inner layer of the tympanic membrane. Derivatives of this pouch are supplied by Mandibular nerve. Second pouch * Contributes the middle ear, palatine tonsils, supplied by the facial nerve. Third pouch * The third pouch possesses dorsal and ventral wings. Derivatives of the dorsal wings include the inferior parathyroid glands, while the ventral wings fuse to form the cytoreticular cells of the thymus. The main nerve supply to the derivatives of this pouch is cranial nerve IX, glossopharyngeal nerve. Fourth pouch Derivatives include: * superior parathyroid glands and ultimobranchial body which forms the paraf ...
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Pharynx
The pharynx (: pharynges) is the part of the throat behind the human mouth, mouth and nasal cavity, and above the esophagus and trachea (the tubes going down to the stomach and the lungs respectively). It is found in vertebrates and invertebrates, though its structure varies across species. The pharynx carries food to the esophagus and air to the larynx. The flap of cartilage called the epiglottis stops food from entering the larynx. In humans, the pharynx is part of the Digestion, digestive system and the conducting zone of the respiratory system. (The conducting zone—which also includes the nostrils of the Human nose, nose, the larynx, trachea, bronchus, bronchi, and bronchioles—filters, warms, and moistens air and conducts it into the lungs). The human pharynx is conventionally divided into three sections: the nasopharynx, oropharynx, and laryngopharynx (hypopharynx). In humans, two sets of pharyngeal muscles form the pharynx and determine the shape of its lumen (anatomy), ...
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Hox Gene
Hox genes, a subset of homeobox, homeobox genes, are a gene cluster, group of related genes that Evolutionary developmental biology, specify regions of the body plan of an embryo along the craniocaudal axis, head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment (for example, legs, antennae, and wings in fruit flies), and Hox genes in vertebrates specify the types and shape of vertebrae that will form. In segmented animals, Hox proteins thus confer segmental or positional identity, but do not form the actual segments themselves. Studies on Hox genes in ciliated larvae have shown they are only expressed in future adult tissues. In larvae with gradual metamorphosis the Hox genes are activated in tissues of the larval body, generally in the trunk region, that will be maintained through metamorp ...
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Hyoid
The hyoid-bone (lingual-bone or tongue-bone) () is a horseshoe-shaped bone situated in the anterior midline of the neck between the chin and the thyroid-cartilage. At rest, it lies between the base of the mandible and the third cervical vertebra. Unlike other bones, the hyoid is only distantly articulated to other bones by muscles or ligaments. It is the only bone in the human body that is not connected to any other bones. The hyoid is anchored by muscles from the anterior, posterior and inferior directions, and aids in tongue movement and swallowing. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. Its name is derived . Structure The hyoid bone is classed as an irregular bone and consists of a central part called the body, and two pairs of horns, the greater and lesser horns. Body The body of the hyoid bone is the central part of the hyoid bone. *At the front ...
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Mandible
In jawed vertebrates, the mandible (from the Latin ''mandibula'', 'for chewing'), lower jaw, or jawbone is a bone that makes up the lowerand typically more mobilecomponent of the mouth (the upper jaw being known as the maxilla). The jawbone is the skull's only movable, posable bone, sharing Temporomandibular joint, joints with the cranium's temporal bones. The mandible hosts the lower Human tooth, teeth (their depth delineated by the alveolar process). Many muscles attach to the bone, which also hosts nerves (some connecting to the teeth) and blood vessels. Amongst other functions, the jawbone is essential for chewing food. Owing to the Neolithic Revolution, Neolithic advent of agriculture (), human jaws evolved to be Human jaw shrinkage, smaller. Although it is the strongest bone of the facial skeleton, the mandible tends to deform in old age; it is also subject to Mandibular fracture, fracturing. Surgery allows for the removal of jawbone fragments (or its entirety) as well a ...
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First Pharyngeal Arch
The pharyngeal arches, also known as visceral arches'','' are transient structures seen in the embryonic development of humans and other vertebrates, that are recognisable precursors for many structures. In fish, the arches support the gills and are known as the branchial arches, or gill arches. In the human embryo, the arches are first seen during the fourth week of development. They appear as a series of outpouchings of mesoderm on both sides of the developing pharynx. The vasculature of the pharyngeal arches are the aortic arches that arise from the aortic sac. Structure In humans and other vertebrates, the pharyngeal arches are derived from all three germ layers (the primary layers of cells that form during embryonic development). Neural crest cells enter these arches where they contribute to features of the skull and facial skeleton such as bone and cartilage. However, the existence of pharyngeal structures before neural crest cells evolved is indicated by the exis ...
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Facial Skeleton
The facial skeleton comprises the ''facial bones'' that may attach to build a portion of the skull. The remainder of the skull is the neurocranium. In human anatomy and development, the facial skeleton is sometimes called the ''membranous viscerocranium'', which comprises the mandible and dermatocranial elements that are not part of the braincase. Structure In the human skull, the facial skeleton consists of fourteen bones in the face: * Inferior turbinal (2) * Lacrimal bones (2) * Mandible * Maxilla (2) * Nasal bones (2) * Palatine bones (2) * Vomer * Zygomatic bones (2) Variations Elements of the ''cartilaginous viscerocranium'' (i.e., splanchnocranial elements), such as the hyoid bone, are sometimes considered part of the facial skeleton. The ethmoid bone (or a part of it) and also the sphenoid bone are sometimes included, but otherwise considered part of the neurocranium. Because the maxillary bones are fused, they are often collectively listed as only one bone. ...
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Skull
The skull, or cranium, is typically a bony enclosure around the brain of a vertebrate. In some fish, and amphibians, the skull is of cartilage. The skull is at the head end of the vertebrate. In the human, the skull comprises two prominent parts: the neurocranium and the facial skeleton, which evolved from the first pharyngeal arch. The skull forms the frontmost portion of the axial skeleton and is a product of cephalization and vesicular enlargement of the brain, with several special senses structures such as the eyes, ears, nose, tongue and, in fish, specialized tactile organs such as barbels near the mouth. The skull is composed of three types of bone: cranial bones, facial bones and ossicles, which is made up of a number of fused flat and irregular bones. The cranial bones are joined at firm fibrous junctions called sutures and contains many foramina, fossae, processes, and sinuses. In zoology, the openings in the skull are called fenestrae, the most ...
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Neural Crest Cells
The neural crest is a ridge-like structure that is formed transiently between the epidermal ectoderm and neural plate during vertebrate development. Neural crest cells originate from this structure through the epithelial-mesenchymal transition, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, dentin, Peripheral nervous system, peripheral and enteric neurons, adrenal medulla and glia. After gastrulation, the neural crest is specified at the border of the neural plate and the non-neural ectoderm. During neurulation, the borders of the neural plate, also known as the neural folds, converge at the dorsal midline to form the neural tube. Subsequently, neural crest cells from the roof plate of the neural tube undergo an Epithelial-mesenchymal transition, epithelial to mesenchymal transition, delaminating from the neuroepithelial cell, neuroepithelium and migrating through the periphery, where they differentiate into ...
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Embryonic Development
In developmental biology, animal embryonic development, also known as animal embryogenesis, is the developmental stage of an animal embryo. Embryonic development starts with the fertilization of an egg cell (ovum) by a sperm, sperm cell (spermatozoon). Once fertilized, the ovum becomes a single diploid cell known as a zygote. The zygote undergoes mitosis, mitotic cell division, divisions with no significant growth (a process known as cleavage (embryo), cleavage) and cellular differentiation, leading to development of a multicellular embryo after passing through an organizational checkpoint during mid-embryogenesis. In mammals, the term refers chiefly to the early stages of prenatal development, whereas the terms fetus and fetal development describe later stages. The main stages of animal embryonic development are as follows: * The zygote undergoes a series of cell divisions (called cleavage) to form a structure called a morula. * The morula develops into a structure called a bla ...
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Germ Layers
A germ layer is a primary layer of cell (biology), cells that forms during embryonic development. The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans (animals that are sister taxa to the sponges) produce two or three primary germ layers. Some animals, like cnidarians, produce two germ layers (the ectoderm and endoderm) making them diploblastic. Other animals such as bilaterians produce a third layer (the mesoderm) between these two layers, making them triploblastic. Germ layers eventually give rise to all of an animal's Tissue (biology), tissues and organ (anatomy), organs through the process of organogenesis. History Caspar Friedrich Wolff observed organization of the early embryo in leaf-like layers. In 1817, Heinz Christian Pander discovered three primordial germ layers while studying chick embryos. Between 1850 and 1855, Robert Remak had further refined the germ cell layer (''Keimblatt'') concept, stating that the external, internal ...
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Vertebrates
Vertebrates () are animals with a vertebral column (backbone or spine), and a cranium, or skull. The vertebral column surrounds and protects the spinal cord, while the cranium protects the brain. The vertebrates make up the subphylum Vertebrata with some 65,000 species, by far the largest ranked grouping in the phylum Chordata. The vertebrates include mammals, birds, amphibians, and various classes of fish and reptiles. The fish include the jawless Agnatha, and the jawed Gnathostomata. The jawed fish include both the Chondrichthyes, cartilaginous fish and the Osteichthyes, bony fish. Bony fish include the Sarcopterygii, lobe-finned fish, which gave rise to the tetrapods, the animals with four limbs. Despite their success, vertebrates still only make up less than five percent of all described animal species. The first vertebrates appeared in the Cambrian explosion some 518 million years ago. Jawed vertebrates evolved in the Ordovician, followed by bony fishes in the Devonian. T ...
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