Lycorine
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Lycorine
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (''Clivia miniata''), surprise lilies ('' Lycoris''), and daffodils ('' Narcissus''). It may be highly poisonous, or even lethal, when ingested in certain quantities. Regardless, it is sometimes used medicinally, a reason why some groups may harvest the very popular ''Clivia miniata''. Source Lycorine is found in different species of ''Amaryllidaceae'' which include flowers and bulbs of daffodil, snowdrop (''Galanthus'') or spider lily (''Lycoris''). Lycorine is the most frequent alkaloid of ''Amaryllidaceae''. The earliest diversification of ''Amaryllidaceae'' was most likely in North Africa and the Iberian peninsula and that lycorine is one of the oldest in the Amaryllidaceae alkaloid biosynthetic pathway. Mechanism of action There is currently very little known about the mechanism of lycorine. There are tentative ideas about how lycorine metabolizes due to a stud ...
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Lycorine Synthesis
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (''Clivia miniata''), surprise lilies ('' Lycoris''), and daffodils ('' Narcissus''). It may be highly poisonous, or even lethal, when ingested in certain quantities. Regardless, it is sometimes used medicinally, a reason why some groups may harvest the very popular ''Clivia miniata''. Source Lycorine is found in different species of ''Amaryllidaceae'' which include flowers and bulbs of daffodil, snowdrop (''Galanthus'') or spider lily (''Lycoris''). Lycorine is the most frequent alkaloid of ''Amaryllidaceae''. The earliest diversification of ''Amaryllidaceae'' was most likely in North Africa and the Iberian peninsula and that lycorine is one of the oldest in the Amaryllidaceae alkaloid biosynthetic pathway. Mechanism of action There is currently very little known about the mechanism of lycorine. There are tentative ideas about how lycorine metabolizes due to a stud ...
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Narcissus (genus)
''Narcissus'' is a genus of predominantly spring flowering perennial plants of the amaryllis family, Amaryllidaceae. Various common names including daffodil,The word "daffodil" is also applied to related genera such as ''Sternbergia'', ''Ismene'' and '' Fritillaria meleagris''. It has been suggested that the word "Daffodil" be restricted to the wild species of the British Isles, '' N. pseudonarcissus''. narcissus, and jonquil are used to describe all or some members of the genus. ''Narcissus'' has conspicuous flowers with six petal-like tepals surmounted by a cup- or trumpet-shaped corona. The flowers are generally white and yellow (also orange or pink in garden varieties), with either uniform or contrasting coloured tepals and corona. ''Narcissus'' were well known in ancient civilisation, both medicinally and botanically, but formally described by Linnaeus in his ''Species Plantarum'' (1753). The genus is generally considered to have about ten sections with approximately ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ...
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Clivia Miniata
''Clivia miniata'', the Natal lily or bush lily, is a species of flowering plant in the genus ''Clivia'' of the family Amaryllidaceae, native to woodland habitats in South Africa (Eastern Cape, Mpumalanga and KwaZulu-Natal provinces) as well as in Eswatini. Given suitable conditions it grows into large clumps and is surprisingly water wise. It is also reportedly naturalized in Mexico. It is a popular plant for shady areas and is commonly seen growing in older established suburbs in most Australian states. It is also popular in New Zealand, Japan, China and the US, particularly California. Description The bush lily has a fleshy, mostly underground stem (rhizome) to in diameter, with numerous fleshy roots. The stem produces long, arching, strap-like leaves growing to about long, arranged in two opposing rows (distichous). The showy, funnel-shaped flowers are produced in an umbel-shaped inflorescence, colored red, orange or yellow, sometimes with a faint, but very sweet perfume. T ...
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Toxic
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large. Sometimes the word is more or less synonymous with poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass ...
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal. The most common cause is an infection of the intestines due to either a virus, bacterium, or parasite—a condition also known as gastroenteritis. These infections are often acquired from food or water that has been contaminated by feces, or directly from another person who is infected. The three types of diarrhea are: short duration watery diarrhea, short duration bloody diarrhea, and persistent diarrhea (lasting more than two weeks, w ...
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Onions
An onion (''Allium cepa'' L., from Latin ''cepa'' meaning "onion"), also known as the bulb onion or common onion, is a vegetable that is the most widely cultivated species of the genus ''Allium''. The shallot is a botanical variety of the onion which was classified as a separate species until 2010. Its close relatives include garlic, scallion, leek, and chive. This genus also contains several other species variously referred to as onions and cultivated for food, such as the Japanese bunching onion (''Allium fistulosum''), the tree onion (''A.'' × ''proliferum''), and the Canada onion (''Allium canadense''). The name ''wild onion'' is applied to a number of ''Allium'' species, but ''A. cepa'' is exclusively known from cultivation. Its ancestral wild original form is not known, although escapes from cultivation have become established in some regions. The onion is most frequently a biennial or a perennial plant, but is usually treated as an annual and harvested in its fi ...
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Emesis
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to alcohol or anesthesia can cause inhalation of vomit, leading to suffocation. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia, and is itself now classified as an eating disorder on its own, purging disorder. Complications Aspiration Vomiting is dangerous if g ...
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Nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. While not painful, it can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat. Over 30 definitions of nausea were proposed in a 2011 book on the topic. Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are gastroenteritis and other gastrointestinal disorders, food poisoning, motion sickness, dizziness, migraine, fainting, low blood sugar, anxiety, and lack of sleep. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by disgust and depression. Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in the US are promethazine, metoclopramide, and the newer ondansetron. The word nausea is from Lat ...
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Vomiting
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the Human nose, nose. Vomiting can be the result of ailments like Food-poisoning, food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to Alcoholic drink, alcohol or anesthesia can cause inhalation of vomit, leading to suffocation. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia nervosa, bulimia, and is itself now classified as an eating disorder on its own, purging di ...
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Quinoline Alkaloids
Quinoline alkaloids are naturally occurring chemical compounds from the group of alkaloids, which are chemically derived from quinoline. Some quinoline alkaloids show antiseptic, convulsive or antineoplastic effects. Examples Alkaloids with a quinoline partial structure are widespread and are usually further subdivided according to their occurrence and biogenetic origin. Among the quinoline alkaloids are the cinchona alkaloids quinine and quinidine, which are important due to their therapeutic potential, furthermore cinchonine and cinchonidine, as well as some furoquinoline alkaloids and acridine alkaloids. Strychnine and brucine, alkaloids of the nux vomica, which have a hydrogenated quinoline system, are also counted among the quinoline alkaloids. Also nitramarine (1-(2-quinolinyl)-β-carboline) belongs to the quinoline alkaloids. File:Chinin.svg, Qinine File:Chinidin.svg, Qinidine File:Cinchonidin.svg, Cinchonidine File:Strychnine2.svg, Strychnine Occurrence The quin ...
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Convulsion
A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is sometimes used as a synonym for ''seizure''. However, not all epileptic seizures lead to convulsions, and not all convulsions are caused by epileptic seizures. Convulsions are also consistent with an electric shock and improper enriched air scuba diving. Non-epileptic convulsions have no relation with epilepsy, and are caused by non-epileptic seizures. Convulsion is a common term generally describing uncontrollable muscle contractions. The term convulsion has been used interchangeably with the word "seizure". Seizures may cause a person to have convulsions, but this is not always the case. Convulsion is a type of seizure that involves bursts of electrical activity in the brain. Occasionally the reason for a convulsion is unfamiliar. A convulsion may be caused ...
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