Leaky Gut Syndrome
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Leaky Gut Syndrome
Leaky gut syndrome is a hypothetical, medically unrecognized condition. Unlike the scientific phenomenon of increased intestinal permeability ("leaky gut"), claims for the existence of "leaky gut syndrome" as a distinct medical condition come mostly from nutritionists and practitioners of alternative medicine. Proponents claim that a "leaky gut" causes chronic inflammation throughout the body that results in a wide range of conditions, including chronic fatigue syndrome, rheumatoid arthritis, lupus, migraines, multiple sclerosis, and autism. There is little evidence to support this hypothesis. Stephen Barrett has described "leaky gut syndrome" as a fad diagnosis and says that its proponents use the alleged condition as an opportunity to sell a number of alternative-health remedies – including diets, herbal preparations, and dietary supplements. In 2009, Seth Kalichman wrote that some pseudoscientists claim that the passage of proteins through a "leaky" gut is the cause ...
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Intestinal Permeability
Intestinal permeability is a term describing the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall, into the rest of the body. The intestine normally exhibits some permeability, which allows nutrients to pass through the gut, while also maintaining a barrier function to keep potentially harmful substances (such as antigens) from leaving the intestine and migrating to the body more widely. In a healthy human intestine, small particles (< 4 Å in radius) can migrate through tight junction claudin pore pathways, and particles up to 10–15 Å (3.5 kDa) can transit through the paracellular space uptake route. There is some evidence abnormally increased intestinal permeability may play a role in some chronic diseases and inflammatory conditions. The most well understood condition with observed increased intestinal permeability is celiac disease. Physiology The barrier formed by the intestinal epithelium separates the externa ...
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Dietary Supplements
A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill (pharmacy), pill, capsule (pharmacy), capsule, tablet (pharmacy), tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order to increase the quantity of their consumption. The class of nutrient compounds includes vitamins, Dietary mineral, minerals, Dietary fiber, fiber, fatty acids, and amino acids. Dietary supplements can also contain substances that have not been confirmed as being essential to life, but are marketed as having a beneficial biological effect, such as plant pigments or polyphenols. Animals can also be a source of supplement ingredients, such as collagen from chickens or fish for example. These are also sold individually and in combination, and may be combined with nutrient ingredients. The European Commission has also established harmonized rules to help insure that food supplements are safe ...
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Diets
The Low Countries comprise the coastal Rhine–Meuse–Scheldt delta region in Western Europe, whose definition usually includes the modern countries of Luxembourg, Belgium and the Netherlands. Both Belgium and the Netherlands derived their names from earlier names for the region, due to ''nether'' meaning "low" and ''Belgica'' being the Latinized name for all the Low Countries, a nomenclature that became obsolete after Belgium's secession in 1830. The Low Countries—and the Netherlands and Belgium—had in their history exceptionally many and widely varying names, resulting in equally varying names in different languages. There is diversity even within languages: the use of one word for the country and another for the adjective form is common. This holds for English, where ''Dutch'' is the adjective form for the country "the Netherlands". Moreover, many languages have the same word for both the country of the Netherlands and the region of the Low Countries, e.g., French ( ...
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Alternative Medicine
Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alternative medicine (CAM), integrated medicine or integrative medicine (IM), and holistic medicine attempt to combine alternative practices with those of mainstream medicine. Alternative therapies share in common that they reside outside of medical science and instead rely on pseudoscience. Traditional practices become "alternative" when used outside their original settings and without proper scientific explanation and evidence. Frequently used derogatory terms for relevant practices are ''new age'' or ''pseudo-'' medicine, with little distinction from quackery. Some alternative practices are based on theories that contradict the established science of how the human body works; others resort to the supernatural or superstitious to explain ...
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Alternative Diagnoses
Alternative or alternate may refer to: Arts, entertainment and media * Alternative (Kamen Rider), Alternative (''Kamen Rider''), a character in the Japanese TV series ''Kamen Rider Ryuki'' * The Alternative (film), ''The Alternative'' (film), a 1978 Australian television film * ''The Alternative'', a radio show hosted by Tony Evans (radio), Tony Evans * 120 Minutes (2004 TV program), ''120 Minutes'' (2004 TV program), an alternative rock music video program formerly known as ''The Alternative'' *''The American Spectator'', an American magazine formerly known as ''The Alternative: An American Spectator'' * Alternative comedy, a range of styles used by comedians and writers in the 1980s * Alternative comics, a genre of comic strips and books * Alternative media, media practices falling outside the mainstreams of corporate communication * Alternative reality, in fiction * Alternative title, the use of a secondary title for a work when it is distributed or sold in other countries Music ...
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Pseudoscience
Pseudoscience consists of statements, beliefs, or practices that claim to be both scientific and factual but are incompatible with the scientific method. Pseudoscience is often characterized by contradictory, exaggerated or falsifiability, unfalsifiable claims; reliance on confirmation bias rather than rigorous attempts at refutation; lack of openness to Peer review, evaluation by other experts; absence of systematic practices when developing Hypothesis, hypotheses; and continued adherence long after the pseudoscientific hypotheses have been experimentally discredited. The demarcation problem, demarcation between science and pseudoscience has scientific, philosophical, and political implications. Philosophers debate the nature of science and the general criteria for drawing the line between scientific theory, scientific theories and pseudoscientific beliefs, but there is general agreement on examples such as ancient astronauts, climate change denial, dowsing, evolution denial, ...
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List Of Topics Characterized As Pseudoscience
This is a list of topics that have, either currently or in the past, been characterized as pseudoscience by academics or researchers. Detailed discussion of these topics may be found on their main pages. These characterizations were made in the context of educating the public about questionable or potentially fraudulent or dangerous claims and practices—efforts to define the nature of science, or humorous parodies of poor scientific reasoning. Criticism of pseudoscience, generally by the scientific community or skeptical organizations, involves critiques of the logical, methodological, or rhetorical bases of the topic in question. Though some of the listed topics continue to be investigated scientifically, others were only subject to scientific research in the past and today are considered refuted, but resurrected in a pseudoscientific fashion. Other ideas presented here are entirely non-scientific, but have in one way or another impinged on scientific domains or practices. M ...
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National Institute For Health And Care Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health and Social Care in England that publishes guidelines in four areas: * the use of health technologies within England's National Health Service (NHS) and NHS Wales (such as the use of new and existing medicines, treatments and procedures) * clinical practice (guidance on the appropriate treatment and care of people with specific diseases and conditions) * guidance for public sector workers on health promotion and ill-health avoidance * guidance for social care services and users. These appraisals are based primarily on evidence-based evaluations of efficacy, safety and cost-effectiveness in various circumstances. It serves both the English NHS and the Welsh NHS. It was set up as the National Institute for Clinical Excellence in 1999, and on 1 April 2005 joined with the Health Development Agency to become the new National Institute for Health a ...
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NHS Choices
The National Health Service (NHS) is the publicly funded healthcare system in England, and one of the four National Health Service systems in the United Kingdom. It is the second largest single-payer healthcare system in the world after the Brazilian Sistema Único de Saúde. Primarily funded by the government from general taxation (plus a small amount from National Insurance contributions), and overseen by the Department of Health and Social Care, the NHS provides healthcare to all legal English residents and residents from other regions of the UK, with most services free at the point of use for most people. The NHS also conducts research through the National Institute for Health and Care Research (NIHR). Free healthcare at the point of use comes from the core principles at the founding of the National Health Service. The 1942 Beveridge cross-party report established the principles of the NHS which was implemented by the Labour government in 1948. Labour's Minister for H ...
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FODMAP
FODMAPs or fermentable oligosaccharides, disaccharides, monosaccharides, and polyols are short chain carbohydrates that are poorly absorbed in the small intestine and are prone to absorb water and ferment in the colon. They include short chain oligosaccharide polymers of fructose (fructans) and galactooligosaccharides (GOS, stachyose, raffinose), disaccharides ( lactose), monosaccharides ( fructose), and sugar alcohols (polyols), such as sorbitol, mannitol, xylitol, and maltitol. Most FODMAPs are naturally present in food and the human diet, but the polyols may be added artificially in commercially prepared foods and beverages. FODMAPs may cause digestive discomfort in some people. The reasons are hypersensitivity to luminal distension, and/or a proclivity to excess water retention and gas production and accumulation, but they do not cause intest ...
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Gluten
Gluten is a structural protein naturally found in certain cereal grains. Although "gluten" often only refers to wheat proteins, in medical literature it refers to the combination of prolamin and glutelin proteins naturally occurring in all grains that have been proved capable of triggering celiac disease. These include any species of wheat (such as common wheat, durum, spelt, khorasan, emmer and einkorn), barley, rye and some oat cultivars, as well as any cross hybrids of these grains (such as triticale). Gluten makes up 75–85% of the total protein in bread wheat. Glutens, especially Triticeae glutens, have unique viscoelastic and adhesive properties, which give dough its elasticity, helping it rise and keep its shape and often leaving the final product with a chewy texture. These properties, and its relatively low cost, make gluten valuable to both food and non-food industries. Wheat gluten is composed of mainly two types of proteins: the glutenins and the gliadins, which i ...
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Probiotic
Probiotics are live microorganisms promoted with claims that they provide health benefits when consumed, generally by improving or restoring the gut microbiota. Probiotics are considered generally safe to consume, but may cause bacteria-host interactions and unwanted side effects in rare cases. There is some evidence that probiotics are beneficial for some conditions, but there is little evidence for many of the health benefits claimed for them. The first discovered probiotic was a certain strain of bacillus in Bulgarian yoghurt, called ''Lactobacillus bulgaricus''. The discovery was made in 1905 by Bulgarian physician and microbiologist Stamen Grigorov. The modern-day theory is generally attributed to Russian Nobel laureate Élie Metchnikoff, who postulated around 1907 that yoghurt-consuming Bulgarian peasants lived longer. A growing probiotics market has led to the need for stricter requirements for scientific substantiation of putative benefits conferred by microorganism ...
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