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Kymograph
A kymograph (from Greek κῦμα, swell or wave + γραφή, writing; also called a kymographion) is an analog device that draws a graphical representation of spatial position over time in which a spatial axis represents time. It basically consists of a revolving drum wrapped with a sheet of paper on which a stylus moves back and forth recording perceived changes of phenomena such as motion or pressure. The kymograph was initially a mechanical and hydraulic device, invented by German physiologist Carl Ludwig in the 1840s, and found its first use as a means to monitor blood pressure. The blood pressure was conveyed by hydraulics and levers to move a stylus that scratched a white trace into soot-covered paper on the revolving drum. Time is represented by the drum's rotation rate, and was recorded by a further stylus driven by a clock or tuning fork. The kymograph almost immediately became the central instrument in physiology and physiology education. Throughout the nineteenth a ...
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Videokymography
Videokymography is a high-speed medical imaging method to visualize the human vocal fold vibration dynamics. It was invented by Jan G. Švec under the guidance of Harm K. Schutte. A digital technique for high-speed visualization of vibration, called videokymography, was developed and applied to the vocal folds. The system uses a modified video camera able to work in two modes: high-speed (nearly 8,000 images/s) and standard (50 images/s in CCIR norm). In the high-speed mode, the camera selects one active horizontal line (transverse to the glottis) from the whole laryngeal image. The successive line images were presented in real time on a commercial TV monitor, filling each video frame from top to bottom. The system makes it possible to observe left-right asymmetries, open quotient, propagation of mucosal waves, movement of the upper and, in the closing phase, the lower margins of the vocal folds, etc. The technique is suitable for further processing and quantification of recorded v ...
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Depth Kymography
Depth-kymography is the 3D display of the human vocal fold vibrations by measuring their vertical and horizontal movements simultaneously, using a specially designed 3D endoscope. This 3D imaging method and the scientific term "Depth-Kymography" were introduced by Dr. Nibu A George, Prof. Frits de Mul and Prof. Harm Schutte. from the University Medical Center Groningen, The Netherlands in 2007. The term "Depth-Kymography" is included in the current medical terminology. Human vocal folds vibrate in a very complex manner. During phonation vocal folds move in both horizontal and vertical directions. The imaging of vocal fold vibrations is achieved by inserting an endoscope through the mouth. The vocal folds are viewed from the top. Hence, with a normal endoscope, only the horizontal movements of the vocal folds are visible. Endoscopes used for the visualization of larynxes are commonly known as Laryngoscopes. With a specially designed 3D laryngoscope, movement of the vocal folds in ...
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Carl Ludwig
Carl Friedrich Wilhelm Ludwig (; 29 December 1816 – 23 April 1895) was a German physician and physiologist. His work as both a researcher and teacher had a major influence on the understanding, methods and apparatus used in almost all branches of physiology. In 1842, Ludwig became a professor of physiology and in 1846 of comparative anatomy. From professorships in Zurich and Vienna he went in 1865 to the University of Leipzig and developed there the Physiological Institute, designated today after him: Carl Ludwig Institute of Physiology.Current website of the Carl-Ludwig-Institute of Physiology http://cliphys.uniklinikum-leipzig.de/ Ludwig researched several topics such as the physiology of blood pressure, urinary excretion, and anesthesia. He received the Copley Medal in 1884 for his research. In 1869, he was elected a foreign member of the Royal Swedish Academy of Sciences. He is credited for inventing the stromuhr. Since 1932, the Carl Ludwig Honorary Medal is awarded by ...
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Analog Device
Analog devices are a combination of both analog machine and analog media that can together measure, record, reproduce, receive or broadcast continuous information, for example, the almost infinite number of grades of transparency, voltage, resistance, rotation, or pressure. In theory, the continuous information in an analog signal has an infinite number of possible values with the only limitation on resolution being the accuracy of the analog device. Analog media are materials with analog properties, such as photographic film, which are used in analog devices, such as cameras. Example devices Non-electrical There are notable non-electrical analog devices, such as some clocks (sundials, water clocks), the astrolabe, slide rules, the governor of a steam engine, the planimeter (a simple device that measures the surface area of a closed shape), Kelvin's mechanical tide predictor, acoustic rangefinders, servomechanisms (e.g. the thermostat), a simple mercury thermomet ...
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Stylus
A stylus (plural styli or styluses) is a writing utensil or a small tool for some other form of marking or shaping, for example, in pottery. It can also be a computer accessory that is used to assist in navigating or providing more precision when using touchscreens. It usually refers to a narrow elongated staff, similar to a modern ballpoint pen. Many styluses are heavily curved to be held more easily. Another widely used writing tool is the stylus used by blind users in conjunction with the slate for punching out the dots in Braille. Etymology The English word ''stylus'' has two plurals: ''styli'' and ''styluses''. The original Latin word was spelled ; the spelling ''stylus'' arose from an erroneous connection with Greek (), 'pillar'.'' Oxford Latin Dictionary'', s.v. "stilus" (2012). The Latin word had several meanings, including "a long, sharply pointed piece of metal; the stem of a plant; a pointed instrument for incising letters; the stylus (as used in literary co ...
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Physiologist
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, '' pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are diffe ...
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Blood Pressure
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in the large arteries. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle. It is measured in millimeters of mercury (mmHg) above the surrounding atmospheric pressure. Blood pressure is one of the vital signs—together with respiratory rate, heart rate, oxygen saturation, and body temperature—that healthcare professionals use in evaluating a patient's health. Normal resting blood pressure, in an adult is approximately systolic over diastolic, denoted as "120/80 mmHg". Globally, the average blood pressure, age standardized, has remained about the same sin ...
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Xenobiotics
A xenobiotic is a chemical substance found within an organism that is not naturally produced or expected to be present within the organism. It can also cover substances that are present in much higher concentrations than are usual. Natural compounds can also become xenobiotics if they are taken up by another organism, such as the uptake of natural human hormones by fish found downstream of sewage treatment plant outfalls, or the chemical defenses produced by some organisms as protection against predators. The term xenobiotics, however, is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e. artificial substances, which did not exist in nature before their synthesis by humans. The term xenobiotic is derived from the Greek words ξένος (xenos) = foreigner, stranger and βίος (bios) = life, plus the Greek suffix ...
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Fulcrum
A fulcrum is the support about which a lever pivots. Fulcrum may also refer to: Companies and organizations * Fulcrum (Anglican think tank), a Church of England think tank * Fulcrum Press, a British publisher of poetry * Fulcrum Wheels, a bicycle wheel manufacturer in Italy Entertainment * ''Fulcrum'' (annual), a United States literary periodical * Fulcrum (''Chuck''), the enemy spy organization on the TV series ''Chuck'' * ''Fulcrum'' (newspaper), a student newspaper at the University of Ottawa * ''Fulcrum'' (sculpture), a 1987 sculpture in London by Richard Serra * The Fulcrum (comics), a supreme being in the Marvel Comics universe * Ahsoka Tano, a character in the animated series ''Star Wars Rebels'' who uses the alias Fulcrum ** Agent Alexsandr Kallus, a character from the same series who took the alias Fulcrum after Ahsoka Tano. Other * Fulcrum (Antarctica), a geological formation in Antarctica * Fulcrum (drumming), part of a percussionist's grip * Fulcrum weeder, ...
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