Kuwanon G
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Kuwanon G
Kuwanon G is an antimicrobial bombesin receptor antagonist, isolated from ''Morus alba ''Morus alba'', known as white mulberry, common mulberry and silkworm mulberry, is a fast-growing, small to medium-sized mulberry tree which grows to tall. It is generally a short-lived tree with a lifespan comparable to that of humans, although ...''. External linksKuwanon G: an antibacterial agent from the root bark of Morus alba against oral pathogensNon-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry
Phenols Cyclohexenes
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Bombesin Receptor
The bombesin receptors are a group of G-protein coupled receptors which bind bombesin. Three bombesin receptors are currently known: BB1, previously known as Neuromedin B receptor BB2, previously known as Gastrin-releasing peptide receptor BB3, previously known as Bombesin-like receptor 3 External links

* G protein-coupled receptors {{transmembranereceptor-stub ...
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Morus Alba
''Morus alba'', known as white mulberry, common mulberry and silkworm mulberry, is a fast-growing, small to medium-sized mulberry tree which grows to tall. It is generally a short-lived tree with a lifespan comparable to that of humans, although there are some specimens known to be more than 250 years old. The species is native to India and is widely cultivated and naturalized elsewhere (including United States, Mexico, Australia, Kyrgyzstan, Argentina, Turkey, Iran, and many others). The white mulberry is widely cultivated to feed the silkworms employed in the commercial production of silk. It is also notable for the rapid release of its pollen, which is launched at greater than half the speed of sound. Its berries are edible when ripe. Description On young, vigorous shoots, the leaves may be up to long, and deeply and intricately lobed, with the lobes rounded. On older trees, the leaves are generally long, unlobed, cordate at the base and rounded to acuminate at the tip, a ...
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Phenols
In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (— O H) bonded directly to an aromatic hydrocarbon group. The simplest is phenol, . Phenolic compounds are classified as simple phenols or polyphenols based on the number of phenol units in the molecule. Phenols are both synthesized industrially and produced by plants and microorganisms. Properties Acidity Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12). Deprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book). Condensation with aldehydes and ketones Phenols are susceptible to Electrophilic aromatic substitutions. Condensation with formald ...
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Chromones
Chromone (or 1,4-benzopyrone) is a derivative of benzopyran with a substituted keto group on the pyran ring. It is an isomer of coumarin. Derivatives of chromone are collectively known as ''chromones''. Most, though not all, chromones are also phenylpropanoids. Examples * 6,7-dimethoxy-2,3-dihydrochromone has been isolated from ''Sarcolobus globosus''. * Eucryphin, a chromone rhamnoside, can be isolated from the bark of ''Eucryphia cordifolia''. * Cromolyn (disodium cromoglicate) was found to inhibit antigen challenge as well as stress induced symptoms.HOWELL, J.B. & ALTOUNYAN, R.E. (1967). A double-blind trial of disodium cromoglycate in the treatment of allergic bronchial asthma. Lancet, 2, 539–542Abstract/ref> Cromoglicate is used as a mast cell stabilizer in allergic rhinitis, asthma and allergic conjunctivitis. * Nedocromil sodium was found to have a somewhat longer half-life than cromolyn; however, production was discontinued in the US in 2008. * Xanthone with a sec ...
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