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Junctional Epidermolysis Bullosa (veterinary Medicine)
Junctional epidermolysis bullosa (JEB) is an inherited disorder that is also known as ''red foot disease'' or ''hairless foal syndrome''. JEB is the result of a genetic mutation that inhibits protein production that is essential for skin adhesion. Therefore, tissues, such as skin and mouth epithelia, are affected. Blisters form over the entire body causing pain and discomfort, and open sores leave newborn foals highly susceptible to secondary infection. The condition can be categorized into two types of mutations: JEB1 and JEB2. JEB1 is found in Belgian Draft horses, as well as other related Draft breeds. In contrast, JEB2 is found in American Saddlebred horses. Breeds affected JEB has documented in Belgian drafts, American Cream Draft, Breton drafts, Comtois, and American Saddlebreds. Of these horses, 12% of Belgians and 4% of Saddlebreds are thought to carry the disorder. Humans JEB also affects the human population. Symptoms are closely related to those that are seen in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belgians
Belgians ( nl, Belgen; french: Belges; german: Belgier) are people identified with the Kingdom of Belgium, a federal state in Western Europe. As Belgium is a multinational state, this connection may be residential, legal, historical, or cultural rather than ethnic. The majority of Belgians, however, belong to two distinct ethnic groups or ''communities'' ( nl, gemeenschap, links=no; french: communauté, links=no) native to the country, i.e. its historical regions: Flemings in Flanders, who speak Dutch; and Walloons in Wallonia, who speak French or Walloon. There is also a substantial Belgian diaspora, which has settled primarily in the United States, Canada, France, and the Netherlands. Etymology The 1830 revolution led to the establishment of an independent country under a provisional government and a national congress. The name "Belgium" was adopted for the country, the word being derived from ''Gallia Belgica'', a Roman province in the northernmost part of Gaul that, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Belgian Draft
The American Belgian Draft is an American breed of heavy draft horse. It derives from the draft horses of Belgium but, as a result of isolation and different selective breeding, became genetically distinct from them in the early part of the twentieth century. It is generally taller and less heavily built, and has a very different distribution of coat colors. History The American Belgian derives from heavy draft horses of Ardennais, Brabant and Flemish stock imported from Belgium in the latter part of the nineteenth century and in the early years of the twentieth. A breed association, the American Association of Importers and Breeders of Belgian Draft Horses, was founded in 1887 in Wabash, Indiana. Imports ceased during the First World War, resumed in the 1930s, and ceased again when the Second World War broke out; Erwin F. Dygert of Iowa bought a horse from the last shipment made from Europe as the war was beginning. From the 1920s the American Belgian was bred to be somew ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Cream Draft
The American Cream Draft is an American breed of draft horse, characterized by the cream or "gold champagne" color of its coat. It was developed in Iowa during the early twentieth century from a cream-colored mare named Old Granny. A breed registry was formed in 1944 but became inactive for several decades when breed numbers dropped due to the mechanization of farming. It was reactivated in 1982 and population numbers have slowly grown since then. It is a rare breed: its conservation status is considered critical by The Livestock Conservancy and the Equus Survival Trust. Characteristics American Creams have refined heads, with flat facial profiles that are neither concave nor convex. They have wide chests, sloping shoulders and short, strong backs. Their ribs are well sprung, and they are short-coupled with well-muscled hindquarters and with strong well-proportioned legs set well apart. They are sure-footed with strong hooves, and their movement is free and easy. According to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breton (horse)
The Trait Breton is a French breed of draught horse. It originated in Brittany, in north-west France, from cross-breeding of local horses with various other breeds. It is strong and muscular, and often has a chestnut coat. There are two principal subtypes: the Postier Breton is an agile harness and light draught breed; the Trait Breton is heavier, and best suited to agricultural work. The Breton was used as a working animal for agricultural and military purposes; in the twenty-first century it is reared principally for horsemeat. A stud book was started in 1909. History The Breton was originally bred for strength and durability."Breton" ''The International Museum of the Horse''. Referenced 1 August 2011. One theory is that they were brought to Europe during the [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Comtois
The Comtois horse is a draft horse that originated in the Jura Mountains on the border between France and Switzerland. Characteristics The Comtois is a light draft horse, with a large head, straight neck, stocky and powerful body and deep girth. They have long, straight backs and short, strong legs with a little feathering and muscular hindquarters. The Comtois sometimes shows a tendency towards sickle hocks. These horses are generally bay silver, but they can also be black silver, bay, black, and chestnut. They usually stand high and weigh .Le Comtois Association Nationale du Cheval de Trait Comtois. Les Haras Nationaux 2010 (in French) Accessed August 2011 History The Comtois horse breed is an old |
American Saddlebred
The American Saddlebred is a horse breed from the United States. This breed is referred to as the "Horse America Made". Descended from riding-type horses bred at the time of the American Revolution, the American Saddlebred includes the Narragansett Pacer, Canadian Pacer, Morgan and Thoroughbred among its ancestors. Developed into its modern type in Kentucky, it was once known as the "Kentucky Saddler", and used extensively as an officer's mount in the American Civil War. In 1891, a breed registry was formed in the United States. Throughout the 20th century, the breed's popularity continued to grow in the United States, and exports began to South Africa and Great Britain. Since the formation of the US registry, almost 250,000 American Saddlebreds have been registered, and can now be found around the world, with separate breed registries established in Great Britain, Australia, continental Europe, and southern Africa. Averaging in height, Saddlebreds are known for their sen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alopecia
Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body. Typically at least the head is involved. The severity of hair loss can vary from a small area to the entire body. Inflammation or scarring is not usually present. Hair loss in some people causes psychological distress. Common types include male- or female-pattern hair loss, alopecia areata, and a thinning of hair known as telogen effluvium. The cause of male-pattern hair loss is a combination of genetics and male hormones; the cause of female pattern hair loss is unclear; the cause of alopecia areata is autoimmune; and the cause of telogen effluvium is typically a physically or psychologically stressful event. Telogen effluvium is very common following pregnancy. Less common causes of hair loss without inflammation or scarring include the pulling out of hair, certain medications including chemotherapy, HIV/AIDS, hypothyroidism, and malnutrition including iron defici ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collagen
Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such as cartilage, bones, tendons, ligaments, and skin. Depending upon the degree of mineralization, collagen tissues may be rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue and accounts for 6% of the weight of the skeletal muscle tissue. The fibroblast is the most common cell that crea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mucous Membranes
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is mostly of endodermal origin and is continuous with the skin at body openings such as the eyes, eyelids, ears, inside the nose, inside the mouth, lips, the genital areas, the urethral opening and the anus. Some mucous membranes secrete mucus, a thick protective fluid. The function of the membrane is to stop pathogens and dirt from entering the body and to prevent bodily tissues from becoming dehydrated. Structure The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. Mucous membranes line the digestive, respiratory and reproductive tract ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gingiva
The gums or gingiva (plural: ''gingivae'') consist of the mucosal tissue that lies over the mandible and maxilla inside the mouth. Gum health and disease can have an effect on general health. Structure The gums are part of the soft tissue lining of the mouth. They surround the teeth and provide a seal around them. Unlike the soft tissue linings of the lips and cheeks, most of the gums are tightly bound to the underlying bone which helps resist the friction of food passing over them. Thus when healthy, it presents an effective barrier to the barrage of periodontal insults to deeper tissue. Healthy gums are usually coral pink in light skinned people, and may be naturally darker with melanin pigmentation. Changes in color, particularly increased redness, together with swelling and an increased tendency to bleed, suggest an inflammation that is possibly due to the accumulation of bacterial plaque. Overall, the clinical appearance of the tissue reflects the underlying histology, b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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