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Isovanilloids
The isovanilloids are compounds which possess an isovanillyl group. They include isovanillyl alcohol, isovanillin, isovanillic acid, ''iso''-acetovanillon, etc. They are isomers of the vanilloids The vanilloids are compounds which possess a vanillyl group. They include vanillyl alcohol, vanillin, vanillic acid, acetovanillon, vanillylmandelic acid, homovanillic acid, capsaicin, etc. Isomers are the isovanilloids. : A number of vanilloid .... : Literature * {{Dead link, date=January 2020 , bot=InternetArchiveBot , fix-attempted=yes Phenols Phenol ethers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vanilloids
The vanilloids are compounds which possess a vanillyl group. They include vanillyl alcohol, vanillin, vanillic acid, acetovanillon, vanillylmandelic acid, homovanillic acid, capsaicin, etc. Isomers are the isovanilloids. : A number of vanilloids, most notably capsaicin, bind to the transient receptor potential vanilloid type 1 (TRPV1) receptor, an ion channel which naturally responds to noxious stimuli such as high temperatures and acidic pH. This action is responsible for the burning sensation experienced after eating spicy peppers. Endogenously generated chemicals that trigger the TRPV1 channel of the vanilloids class are referred to as endovanilloids including anandamide, 20-Hydroxyeicosatetraenoic_acid(20-HETE) ,N-Arachidonoyl_dopamine (NADA) and N-oleoyl-dopamine. : Outside the food industry vanilloids such as nonivamide are used commercially in pepper spray formulations. Other vanilloids which act at TRPV1 include resiniferatoxin Resiniferatoxin (RTX) is a natura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isovanillin
Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. It is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid, which could make it a candidate drug for use in alcohol aversion therapy. Isovanillin can be used as a precursor in the chemical total synthesis of morphine. The proposed metabolism of isovanillin (and vanillin) in rat has been described in literature, and is part of the WikiPathways machine readable pathway collection. See also * Vanillin * 2-Hydroxy-5-methoxybenzaldehyde * ortho-Vanillin ''ortho''-Vanillin (2-hydroxy-3-methoxybenzaldehyde) is an organic solid present in the extracts and essential oils of many plants. Its functional groups include aldehyde, ether and phenol. ''ortho''-Vanillin, a compound of the formula C8H8O3, is ... * 2-Hydroxy-4-methoxybenzaldehyde References Hydroxybenzaldehydes Flavors Perfume ingredients Phenol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isovanillin
Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. It is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid, which could make it a candidate drug for use in alcohol aversion therapy. Isovanillin can be used as a precursor in the chemical total synthesis of morphine. The proposed metabolism of isovanillin (and vanillin) in rat has been described in literature, and is part of the WikiPathways machine readable pathway collection. See also * Vanillin * 2-Hydroxy-5-methoxybenzaldehyde * ortho-Vanillin ''ortho''-Vanillin (2-hydroxy-3-methoxybenzaldehyde) is an organic solid present in the extracts and essential oils of many plants. Its functional groups include aldehyde, ether and phenol. ''ortho''-Vanillin, a compound of the formula C8H8O3, is ... * 2-Hydroxy-4-methoxybenzaldehyde References Hydroxybenzaldehydes Flavors Perfume ingredients Phenol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioorganic & Medicinal Chemistry Letters
''Bioorganic & Medicinal Chemistry Letters'' is a scientific journal focusing on the results of research on the molecular structure of biological organisms and the interaction of biological targets with chemical agents. It is published by Elsevier, which also publishes ''Bioorganic & Medicinal Chemistry ''Bioorganic & Medicinal Chemistry'' is a scientific journal focusing on the results of research on the molecular structure of biological organisms and the interaction of biological targets with chemical agents.Bioorganic & Medicinal Chemistry' It ...'' for longer works. Biochemistry journals Elsevier academic journals English-language journals Medicinal chemistry journals {{biochem-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenols
In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (— O H) bonded directly to an aromatic hydrocarbon group. The simplest is phenol, . Phenolic compounds are classified as simple phenols or polyphenols based on the number of phenol units in the molecule. Phenols are both synthesized industrially and produced by plants and microorganisms. Properties Acidity Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12). Deprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book). Condensation with aldehydes and ketones Phenols are susceptible to Electrophilic aromatic substitutions. Condensation with formald ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
