|
Imipramine Pamoate
Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant (TCA) mainly used in the treatment of depression (mood), depression. It is also effective in treating anxiety and panic disorder. The drug is also used to treat nocturnal enuresis, bedwetting. Imipramine is taken oral administration, by mouth. Common side effects of imipramine include dry mouth, drowsiness, dizziness, hypotension, low blood pressure, tachycardia, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose of the medication can result in death. Imipramine appears to work by Serotonin–norepinephrine reuptake inhibitor, increasing levels of serotonin and norepinephrine and by receptor antagonist, blocking certain serotonin, adrenergic receptor, adrenergic, histamine receptor, histamine, and acetylcholine receptor, cholinergic receptor (biochemistry), receptors. Imipramine was discovered in 1951 and was introduced for medical use in 1957. It was the first TC ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oral Administration
Oral administration is a route of administration where a substance is taken through the mouth. Per os abbreviated to P.O. is sometimes used as a direction for medication to be taken orally. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example. Oral administration can be easier and less painful than other routes, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients willing and able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
