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Information Bias (epidemiology)
In epidemiology, information bias refers to bias arising from measurement error. Information bias is also referred to as observational bias and misclassification. ''A Dictionary of Epidemiology'', sponsored by the International Epidemiological Association, defines this as the following: "1. A flaw in measuring exposure, covariate, or outcome variables that results in different quality (accuracy) of information between comparison groups. The occurrence of information biases may not be independent of the occurrence of selection biases. 2. Bias in an estimate arising from measurement errors." Misclassification Misclassification thus refers to measurement error. There are two types of misclassification in epidemiological research: non-differential misclassification and differential misclassification. Nondifferential misclassification Nondifferential misclassification is when all classes, groups, or categories of a variable (whether exposure, outcome, or covariate) have the same e ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ...
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Bias (statistics)
Statistical bias is a systematic tendency which causes differences between results and facts. The bias exists in numbers of the process of data analysis, including the source of the data, the estimator chosen, and the ways the data was analyzed. Bias may have a serious impact on results, for example, to investigate people's buying habits. If the sample size is not large enough, the results may not be representative of the buying habits of all the people. That is, there may be discrepancies between the survey results and the actual results. Therefore, understanding the source of statistical bias can help to assess whether the observed results are close to the real results. Bias can be differentiated from other mistakes such as accuracy (instrument failure/inadequacy), lack of data, or mistakes in transcription (typos). Bias implies that the data selection may have been skewed by the collection criteria. Bias does not preclude the existence of any other mistakes. One may have a poo ...
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Observational Error
Observational error (or measurement error) is the difference between a measured value of a quantity and its true value.Dodge, Y. (2003) ''The Oxford Dictionary of Statistical Terms'', OUP. In statistics, an error is not necessarily a " mistake". Variability is an inherent part of the results of measurements and of the measurement process. Measurement errors can be divided into two components: ''random'' and ''systematic''. Random errors are errors in measurement that lead to measurable values being inconsistent when repeated measurements of a constant attribute or quantity are taken. Systematic errors are errors that are not determined by chance but are introduced by repeatable processes inherent to the system. Systematic error may also refer to an error with a non-zero mean, the effect of which is not reduced when observations are averaged. Measurement errors can be summarized in terms of accuracy and precision. Measurement error should not be confused with measurement unce ...
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Observation
Observation is the active acquisition of information from a primary source. In living beings, observation employs the senses. In science, observation can also involve the perception and recording of data via the use of scientific instruments. The term may also refer to any data collected during the scientific activity. Observations can be qualitative, that is, only the absence or presence of a property is noted, or quantitative if a numerical value is attached to the observed phenomenon by counting or measuring. Science The scientific method requires observations of natural phenomena to formulate and test hypotheses. It consists of the following steps: # Ask a question about a natural phenomenon # Make observations of the phenomenon # Formulate a hypothesis that tentatively answers the question # Predict logical, observable consequences of the hypothesis that have not yet been investigated # Test the hypothesis' predictions by an experiment, observational study, field study, or ...
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International Epidemiological Association
The International Epidemiological Association (IEA) is a worldwide association with more than 2000 members in over 100 different countries, who follow the aims of the association to facilitate communication amongst those engaged in research and teaching of epidemiology throughout the world, and to encourage its use in all fields of health including social, community and preventative medicine.IEA. "International Epidemiological Association Council Handbook". 6th ed2006. These aims are achieved by holding scientific meetings and seminars, by publication of journals, reports, translations of books, by contact amongst members and by other activities consistent with these aims. Members are accepted without regard to race, religion, sex, political affiliation or country of origin. The association publishes its own Journal, the ''International Journal of Epidemiology'' (IJEInternational Journal of Epidemiology which is published bi-monthly, a complimentary copy of which is included in th ...
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Covariate
Dependent and independent variables are variables in mathematical modeling, statistical modeling and experimental sciences. Dependent variables receive this name because, in an experiment, their values are studied under the supposition or demand that they depend, by some law or rule (e.g., by a mathematical function), on the values of other variables. Independent variables, in turn, are not seen as depending on any other variable in the scope of the experiment in question. In this sense, some common independent variables are time, space, density, mass, fluid flow rate, and previous values of some observed value of interest (e.g. human population size) to predict future values (the dependent variable). Of the two, it is always the dependent variable whose variation is being studied, by altering inputs, also known as regressors in a statistical context. In an experiment, any variable that can be attributed a value without attributing a value to any other variable is called an ind ...
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Selection Bias
Selection bias is the bias introduced by the selection of individuals, groups, or data for analysis in such a way that proper randomization is not achieved, thereby failing to ensure that the sample obtained is representative of the population intended to be analyzed. It is sometimes referred to as the selection effect. The phrase "selection bias" most often refers to the distortion of a statistical analysis, resulting from the method of collecting samples. If the selection bias is not taken into account, then some conclusions of the study may be false. Types Sampling bias Sampling bias is systematic error due to a non-random sample of a population, causing some members of the population to be less likely to be included than others, resulting in a biased sample, defined as a statistical sample of a population (or non-human factors) in which all participants are not equally balanced or objectively represented. It is mostly classified as a subtype of selection bias, sometimes sp ...
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Binary Variable
Binary data is data whose unit can take on only two possible states. These are often labelled as 0 and 1 in accordance with the binary numeral system and Boolean algebra. Binary data occurs in many different technical and scientific fields, where it can be called by different names including ''bit'' (binary digit) in computer science, ''truth value'' in mathematical logic and related domains and ''binary variable'' in statistics. Mathematical and combinatoric foundations A discrete variable that can take only one state contains zero information, and is the next natural number after 1. That is why the bit, a variable with only two possible values, is a standard primary unit of information. A collection of bits may have states: see binary number for details. Number of states of a collection of discrete variables depends exponentially on the number of variables, and only as a power law on number of states of each variable. Ten bits have more () states than three decimal digits ...
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Dichotomous
A dichotomy is a partition of a whole (or a set) into two parts (subsets). In other words, this couple of parts must be * jointly exhaustive: everything must belong to one part or the other, and * mutually exclusive: nothing can belong simultaneously to both parts. If there is a concept A, and it is split into parts B and not-B, then the parts form a dichotomy: they are mutually exclusive, since no part of B is contained in not-B and vice versa, and they are jointly exhaustive, since they cover all of A, and together again give A. Such a partition is also frequently called a bipartition. The two parts thus formed are complements. In logic, the partitions are opposites if there exists a proposition such that it holds over one and not the other. Treating continuous variables or multicategorical variables as binary variables is called dichotomization. The discretization error inherent in dichotomization is temporarily ignored for modeling purposes. Etymology The term ''di ...
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Average
In ordinary language, an average is a single number taken as representative of a list of numbers, usually the sum of the numbers divided by how many numbers are in the list (the arithmetic mean). For example, the average of the numbers 2, 3, 4, 7, and 9 (summing to 25) is 5. Depending on the context, an average might be another statistic such as the median, or mode. For example, the average personal income is often given as the median—the number below which are 50% of personal incomes and above which are 50% of personal incomes—because the mean would be higher by including personal incomes from a few billionaires. For this reason, it is recommended to avoid using the word "average" when discussing measures of central tendency. General properties If all numbers in a list are the same number, then their average is also equal to this number. This property is shared by each of the many types of average. Another universal property is monotonicity: if two lists of numbers ''A'' and ...
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Null (mathematics)
In mathematics, the word null (from german: null meaning "zero", which is from la, nullus meaning "none") is often associated with the concept of zero or the concept of nothing. It is used in varying context from "having zero members in a set" (e.g., null set) to "having a value of zero" (e.g., null vector). In a vector space, the null vector is the neutral element of vector addition; depending on the context, a null vector may also be a vector mapped to some ''null'' by a function under consideration (such as a quadratic form coming with the vector space, see null vector, a linear mapping given as matrix product or dot product, a seminorm in a Minkowski space, etc.). In set theory, the empty set, that is, the set with zero elements, denoted "" or "∅", may also be called null set. In measure theory, a null set is a (possibly nonempty) set with zero measure. A null space of a mapping is the part of the domain that is mapped into the null element of the image (the inverse image ...
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