Hypoxen
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Hypoxen
Sodium polydihydroxyphenylene thiosulfonate (гипоксен, Hypoxen) is under laboratory studies in Russia as a potential regulator of cell metabolism. It is purported to affect mitochondrial function, though this has not been proven in any high-quality, peer-reviewed publications. It is registered in Russia as an antihypoxic agent, but has not been subjected to any clinical trials meeting internationally accepted standards, and has no regulatory approval as a prescription drug outside Russia and some former Soviet states. Although called an "oxygen booster" in public media to imply its potential to "increase endurance and reduce fatigue", there is no scientific evidence it has this property, and it is not used in conventional cardiology as a therapy for treating heart disease. Hypoxen is sold online without a prescription, mainly from Russian websites, and does not appear to be sold in health stores in the United States. Hypoxen is not listed on the prohibited subs ...
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Kamila Valieva
Kamila Valeryevna Valieva (russian: Камила Валерьевна Валиева; born 26 April 2006) is a Russian figure skater. She is the 2022 European champion, 2021 Rostelecom Cup champion, 2021 Skate Canada International champion, 2022 Russian national champion, and 2021 Russian National silver medalist. She is also a provisional 2022 Olympic champion in the team event pending the conclusion of a WADA investigation. During the 2022 Winter Olympics, a sample that Valieva had submitted for a drug test in December tested positive for trimetazidine, which is banned in sports competition for increasing endurance. As of mid-February investigations were ongoing. Valieva is the current world record holder for the women's short program, free skating and total scores. She has set nine world records during her career. She is the first female skater to break the 250-, 260- and 270-point thresholds in the total score (all within one season), the first to break the 170- an ...
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Trimetazidine
Trimetazidine (IUPAC: 1-(2,3,4-trimethoxybenzyl)piperazine) is a drug for angina pectoris (chest pain associated with blood flow to the heart) sold under many brand names. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). It is an anti-ischemic (antianginal) metabolic agent of the fatty acid oxidation inhibitor class, meaning that it improves myocardial glucose utilization through inhibition of fatty acid metabolism. Medical uses Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for tinnitus and dizziness. It is taken twice a day. In 2012, the European Medicines Agency (EMA) finished a review of benefits and risks of trimetazidine and recommended restricting use of trimetazidine-containing medicines to just as an additional treatment of angina pectoris in cases of inadequate control by or intolerance to first-line anti ...
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Health Food Store
A health food store (or health food shop) is a type of grocery store that primarily sells health foods, organic foods, local produce, and often nutritional supplements. Health food stores typically offer a wider or more specialized selection of foods than conventional grocery stores for their customers, for example people with special dietary needs, such as people who are allergic to the gluten in wheat or some other substance, and for people who observe vegetarian, vegan, raw food, organic, or other alternative diets. Health food The term '' health food'' has been used since the 1920s to refer to specific foods claimed to be especially beneficial to health, although the term has no official definition. Some terms that are associated with health food are macrobiotics, natural foods, organic foods and whole foods. Macrobiotics is a diet focusing primarily on whole cereals. Whole cereals, along with other ''whole foods'', are foods that are minimally processed. Whole cerea ...
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Meldonium
Meldonium (INN; trade name Mildronate, among others) is a limited-market pharmaceutical, developed in 1970 by Ivars Kalviņš at the USSR Latvia Institute of Organic Synthesis, and now manufactured by the Latvian pharmaceutical company Grindeks and several generic manufacturers. It is primarily distributed in Eastern European countries as an anti- ischemia medication. Since 1 January 2016, it has been on the World Anti-Doping Agency (WADA) list of substances banned from use by athletes. Meldonium can be used as a metabolic modulator, changing how some hormones accelerate or slow down enzymatic reactions in the body. However, there are debates over its use as an athletic performance enhancer. Some athletes are known to have used meldonium before it was banned. Nevertheless, many athletes have been suspended or disqualified officially in relation to this drug. Medical use Meldonium may be used to treat coronary artery disease. These heart problems may sometimes lead to ...
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2022 Winter Olympics
The 2022 Winter Olympics (2022年冬季奥林匹克运动会), officially called the XXIV Olympic Winter Games () and commonly known as Beijing 2022 (2022), was an international winter multi-sport event held from 4 to 20 February 2022 in Beijing, China, and surrounding areas with competition in selected events beginning 2 February 2022. It was the 24th edition of the Winter Olympic Games. Beijing was selected as host city in 2015 at the 128th IOC Session in Kuala Lumpur, Malaysia, marking its second time hosting the Olympics, and the last of three consecutive Olympics hosted in East Asia following the 2018 Winter Olympics in Pyeongchang County, South Korea, and the 2020 Summer Olympics in Tokyo, Japan. Having previously hosted the 2008 Summer Olympics, Beijing became the first city to have hosted both the Summer and Winter Olympics. The venues for the Games were concentrated upon Beijing, its suburb Yanqing District, and Zhangjiakou, with some events (including the ceremo ...
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Figure Skating
Figure skating is a sport in which individuals, pairs, or groups perform on figure skates on ice. It was the first winter sport to be included in the Olympic Games, when contested at the 1908 Olympics in London. The Olympic disciplines are men's singles, women's singles, pair skating, and ice dance; the four individual disciplines are also combined into a team event, first included in the Winter Olympics in 2014. The non-Olympic disciplines include synchronized skating, Theater on Ice, and four skating. From intermediate through senior-level competition, skaters generally perform two programs (the short program and the free skate), which, depending on the discipline, may include spins, jumps, moves in the field, lifts, throw jumps, death spirals, and other elements or moves. Figure skaters compete at various levels from beginner up to the Olympic level (senior) at local, regional, sectional, national, and international competitions. The International Skating Unio ...
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United States Anti-Doping Agency
The United States Anti-Doping Agency (USADA, ) is a non-profit, non-governmental 501(c)(3) organization and the national anti- doping organization (NADO) for the United States. To protect clean competition and the integrity of sport and prevent doping in the United States with a performance-enhancing substance, the USADA provides education, leads scientific initiatives, conducts testing, and oversees the results management process. Headquartered in Colorado Springs, Colorado, USADA is a signatory to the World Anti-Doping Code, which harmonizes anti-doping practices around the world and is widely considered the basis for the strongest and strictest anti-doping programs to prevent doping in sport. In 2001, USADA was recognized by the U.S. Congress as "the official anti-doping agency for Olympic, Pan American and Paralympic sport in the United States." While USADA is not a government entity, it is partly funded by the Office of National Drug Control Policy (ONDCP), with its rem ...
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World Anti-Doping Agency
The World Anti-Doping Agency (WADA; french: Agence mondiale antidopage, AMA) is a foundation initiated by the International Olympic Committee based in Canada to promote, coordinate, and monitor the fight against drugs in sports. The agency's key activities include scientific research, education, development of anti-doping capacities, and monitoring of the World Anti-Doping Code, whose provisions are enforced by the UNESCO International Convention Against Doping in Sport. The aims of the Council of Europe Anti-Doping Convention and the United States Anti-Doping Agency are also closely aligned with those of WADA. History The World Anti-Doping Agency is a foundation created through a collective initiative led by the International Olympic Committee (IOC). It was set up on 10 November 1999 in Lausanne, Switzerland, as a result of what was called the "Declaration of Lausanne", to promote, coordinate and monitor the fight against drugs in sports. Since 2002, the organization's head ...
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Doping In Sport
In competitive sports, doping is the use of banned athletic performance-enhancing drugs by athletic competitors as a way of cheating in sports. The term ''doping'' is widely used by organizations that regulate sporting competitions. The use of drugs to enhance performance is considered unethical, and therefore prohibited, by most international sports organizations, including the International Olympic Committee. Furthermore, athletes (or athletic programs) taking explicit measures to evade detection exacerbate the ethical violation with overt deception and cheating. The origins of doping in sports go back to the very creation of sport itself. From ancient usage of substances in chariot racing to more recent controversies in doping in baseball, doping in tennis, doping at the Olympic Games, and doping at the Tour de France, popular views among athletes have varied widely from country to country over the years. The general trend among authorities and sporting organizations over ...
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Metabolism
Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as '' catabolic'' – the ''breaking down'' of compounds (for example, of glucose to pyruvate ...
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Mitochondria
A mitochondrion (; ) is an organelle found in the cells of most Eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'' was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase coined by Philip Siekevitz in a 1957 article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). A large number of unicellular organisms, such as microsporidia, parabasalids and diplomonads, have reduced or transformed their mitochondria into other structures. One eukaryote, ''Monocercomonoides'', is known to have completely lost its mitochondria, and one multicellular organism, ' ...
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Cardiology
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat adult heart disease. Surgical aspects are not included in ...
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