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Hydroxytyrosol
Hydroxytyrosol is an organic compound with the formula . Classified as a phenylethanoid, i.e. a relative of phenethyl alcohol, Its derivatives are found in a variety of natural sources, notably olive oils and wines. The compound is colorless solid. although commercial samples are often beige. It is a derivative, formally speaking, of catechol. It or its derivatives occurs in olives and in wines Occurrence Olives left, Oleuropein, a bitter component found in green olive skin, is an ester of hydroxytyrosol.">olive.html" ;"title="Oleuropein, a bitter component found in green olive">Oleuropein, a bitter component found in green olive skin, is an ester of hydroxytyrosol. The olives, leaves, and olive pulp contain large amounts of hydroxytyrosol derivative Oleuropein, more so than olive oil). Unprocessed, green (unripe) olives, contain between 4.3 and 116 mg of hydroxytyrosol per 100g of olives, while unprocessed, black (ripe) olives contain up to 413.3 mg per 100g. The r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrosol
Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, i.e. a derivative of phenethyl alcohol, It is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oil. Research As an antioxidant, tyrosol may protect cells against injury due to oxidation ''in vitro''. Although it is not as potent as other antioxidants present in olive oil (e.g., hydroxytyrosol), its higher concentration and good bioavailability indicate that it may have an important overall effect. Tyrosol may also be cardioprotective. Trosol-treated animals showed significant increase in the phosphorylation of Akt, eNOS and FOXO3a. In addition, tyrosol also induced the expression of the protein SIRT1 in the heart after myocardial infarction in a rat MI model. Tyrosol forms esters with a variety of organic acids. See also * tyrosinol, * hydroxytyrosol Hydroxytyrosol is an organic compound with the formula . Classified ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrosol
Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, i.e. a derivative of phenethyl alcohol, It is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oil. Research As an antioxidant, tyrosol may protect cells against injury due to oxidation ''in vitro''. Although it is not as potent as other antioxidants present in olive oil (e.g., hydroxytyrosol), its higher concentration and good bioavailability indicate that it may have an important overall effect. Tyrosol may also be cardioprotective. Trosol-treated animals showed significant increase in the phosphorylation of Akt, eNOS and FOXO3a. In addition, tyrosol also induced the expression of the protein SIRT1 in the heart after myocardial infarction in a rat MI model. Tyrosol forms esters with a variety of organic acids. See also * tyrosinol, * hydroxytyrosol Hydroxytyrosol is an organic compound with the formula . Classified ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleuropein
Oleuropein is a glycosylated seco-iridoid, a type of phenolic bitter compound found in green olive skin, flesh, seeds, and leaves. The term oleuropein is derived from the botanical name of the olive tree, ''Olea europaea''. Because of its bitter taste, oleuropein must be completely removed or decomposed to make olives edible. During processing of bitter and inedible green olives for consumption as table olives, oleuropein is removed from olives via a number of methods, including by immersion in lye. Chemical treatment Oleuropein is a derivative of elenolic acid linked to the orthodiphenol hydroxytyrosol by an ester bond and to a molecule of glucose by a glycosidic bond. When olives are immersed in a lye solution, the alkaline conditions lead to hydrolysis of the ester bond. The basic conditions also significantly increases the solubility of these derivatives, facilitating their release into the lye solution. The high pH accelerates the oxidation of the phenolics, leading to blac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleuropein
Oleuropein is a glycosylated seco-iridoid, a type of phenolic bitter compound found in green olive skin, flesh, seeds, and leaves. The term oleuropein is derived from the botanical name of the olive tree, ''Olea europaea''. Because of its bitter taste, oleuropein must be completely removed or decomposed to make olives edible. During processing of bitter and inedible green olives for consumption as table olives, oleuropein is removed from olives via a number of methods, including by immersion in lye. Chemical treatment Oleuropein is a derivative of elenolic acid linked to the orthodiphenol hydroxytyrosol by an ester bond and to a molecule of glucose by a glycosidic bond. When olives are immersed in a lye solution, the alkaline conditions lead to hydrolysis of the ester bond. The basic conditions also significantly increases the solubility of these derivatives, facilitating their release into the lye solution. The high pH accelerates the oxidation of the phenolics, leading to blac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleuropein Structure
Oleuropein is a glycosylated seco-iridoid, a type of phenolic bitter compound found in green olive skin, flesh, seeds, and leaves. The term oleuropein is derived from the botanical name of the olive tree, ''Olea europaea''. Because of its bitter taste, oleuropein must be completely removed or decomposed to make olives edible. During processing of bitter and inedible green olives for consumption as table olives, oleuropein is removed from olives via a number of methods, including by immersion in lye. Chemical treatment Oleuropein is a derivative of elenolic acid linked to the orthodiphenol hydroxytyrosol by an ester bond and to a molecule of glucose by a glycosidic bond. When olives are immersed in a lye solution, the alkaline conditions lead to hydrolysis of the ester bond. The basic conditions also significantly increases the solubility of these derivatives, facilitating their release into the lye solution. The high pH accelerates the oxidation of the phenolics, leading to blac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Verbascoside
Verbascoside is a caffeoyl phenylethanoid glycoside in which the phenylpropanoid caffeic acid and the phenylethanoid hydroxytyrosol form an ester and an ether bond respectively, to the rhamnose part of a disaccharide, namely β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-(4-O-caffeoyl)-glucopyranoside. Occurrences Natural occurrences Verbascoside can be found in species in all the families of the order Lamiales (syn. Scrophulariales). Only two examples are known from outside the order, in the clade Asterids. ; in the Lamiales In the family Lamiaceae, it can be found in the medicinal plants in the genus '' Phlomis'', in the Scrophulariaceae, in '' Verbascum phlomoides'', '' Verbascum mallophorum'', or, in the family Buddlejaceae, in '' Buddleja globosa'' or '' Buddleja cordata'', in the family Bignoniaceae, in '' Pithecoctenium sp'' and '' Tynanthus panurensis'', in the family Orobanchaceae, in '' Cistanche sp'' and '' Orobanche rapum-genistae'', ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Echinacoside
Echinacoside is a natural phenol. It is a caffeic acid glycoside from the phenylpropanoid class. It is constituted from a trisaccharide consisting of two glucose and one rhamnose moieties glycosidically linked to one caffeic acid and one dihydroxyphenylethanol (hydroxytyrosol) residue at the centrally situated rhamnose. This water-soluble glycoside is a distinctive secondary metabolite of ''Echinacea angustifolia'' and '' Echinacea pallida'' (to about 1%) but only occurs in trace amounts in ''Echinacea purpurea''. It is also isolated from '' Cistanche spp''. It was first isolated by Stoll et al. in 1950 from the roots of ''Echinacea angustifolia''. It shows weak antibiotic activity in vitro against ''Staphylococcus aureus ''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive ...'' and '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylethanoids
Phenylethanoids are a type of phenolic compounds characterized by a phenethyl alcohol structure. Tyrosol and hydroxytyrosol are examples of such compounds. Glycosides The red deadnettle (''Lamium purpureum'') contains phenylethanoid glycosides named lamiusides A, B, C, D and E. The aerial parts of '' Stachys officinalis'' contain phenylethanoid glycosides, ( betonyosides A, B, C, D, E and F). Chemical investigation of methanol extracts from '' Pithecoctenium crucigerum'' (Bignoniaceae) showed the presence of five phenylethanoid glycosides ( verbascoside, isoverbascoside, forsythoside B, jionoside D and leucosceptoside B), these all active against DPPH DPPH is a common abbreviation for the organic chemical compound 2,2-diphenyl-1-picrylhydrazyl. It is a dark-colored crystalline powder composed of stable free radical molecules. DPPH has two major applications, both in laboratory research: one is .... Verbascoside and echinacoside are phenylethanoid and phenylpr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olive Oil
Olive oil is a liquid fat obtained from olives (the fruit of ''Olea europaea''; family Oleaceae), a traditional tree crop of the Mediterranean Basin, produced by pressing whole olives and extracting the oil. It is commonly used in cooking: for frying foods or as a salad dressing. It can be found in some cosmetics, pharmaceuticals, soaps, and fuels for traditional oil lamps. It also has additional uses in some religions. The olive is one of three core food plants in Mediterranean cuisine; the other two are wheat and grapes. Olive trees have been grown around the Mediterranean since the 8th millennium BC. In 2019–2020, world production of olive oil was . Spain was the largest producer followed by Italy, Tunisia, Greece, Turkey and Morocco. San Marino has by far the largest per capita consumption of olive oil worldwide. The composition of olive oil varies with the cultivar, altitude, time of harvest, and extraction process. It consists mainly of oleic acid (up to 83%), with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylethanoid
Phenylethanoids are a type of phenolic compounds characterized by a phenethyl alcohol structure. Tyrosol and hydroxytyrosol are examples of such compounds. Glycosides The red deadnettle (''Lamium purpureum'') contains phenylethanoid glycosides named lamiusides A, B, C, D and E. The aerial parts of '' Stachys officinalis'' contain phenylethanoid glycosides, ( betonyosides A, B, C, D, E and F). Chemical investigation of methanol extracts from '' Pithecoctenium crucigerum'' (Bignoniaceae) showed the presence of five phenylethanoid glycosides ( verbascoside, isoverbascoside, forsythoside B, jionoside D and leucosceptoside B), these all active against DPPH DPPH is a common abbreviation for the organic chemical compound 2,2-diphenyl-1-picrylhydrazyl. It is a dark-colored crystalline powder composed of stable free radical molecules. DPPH has two major applications, both in laboratory research: one is .... Verbascoside and echinacoside are phenylethanoid and phenylpro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mediterranean Diet
The Mediterranean diet is a diet inspired by the eating habits of people who live near the Mediterranean Sea. When initially formulated in the 1960s, it drew on the cuisines of Greece, Italy, France and Spain. In decades since, it has also incorporated other Mediterranean cuisines, such as those in Turkey, the Balkans, Lebanon, Syria, North Africa and Portugal. The principal aspects of this diet include proportionally high consumption of unprocessed cereals, legumes, olive oil, fruits, and vegetables, and moderate consumption of fish, dairy products (mostly cheese and yogurt), and meat products. Olive oil has been studied as a potential health factor for reducing all-cause mortality and the risk of chronic diseases. The Mediterranean diet is associated with a reduction in all-cause mortality in observational studies. There is evidence that the Mediterranean diet lowers the risk of heart disease and early death. The American Heart Association and American Diabetes Association r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GPER Agonists
G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the ''GPER'' gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. Discovery The classical estrogen receptors first characterized in 1958 are water-soluble proteins located in the interior of cells that are activated by estrogenenic hormones such as estradiol and several of its metabolites such as estrone or estriol. These proteins belong to the nuclear hormone receptor class of transcription factors that regulate gene transcription. Since it takes time for genes to be transcribed into RNA and translated into protein, the effects of estrogens binding to these classical estrogen receptors is delayed. However, estrogens are also known to have effects that are too fast to be caused by regulation of gene transcription. In 2005, it was discovered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
