Haplogroup W (mtDNA)
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Haplogroup W (mtDNA)
Haplogroup W is a human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup W is believed to have originated around 23,900 years ago in Western Asia. It is descended from the haplogroup N2. Distribution Haplogroup W is found in Europe, Western Asia, and South Asia. It is widely distributed at low frequencies, with a high concentration in Northern Pakistan. Haplogroup W is also found in the Maghreb among Algerians (1.08%-3.23%)S5 Table/ref> and in Siberia among Yakuts (6/423 = 1.42%Sardana A Fedorova, Maere Reidla, Ene Metspalu, ''et al.'', "Autosomal and uniparental portraits of the native populations of Sakha (Yakutia): implications for the peopling of Northeast Eurasia." ''BMC Evolutionary Biology'' 2013, 13:127. http://www.biomedcentral.com/1471-2148/13/127). Additionally, the clade has been observed among ancient Egyptian mummies excavated at the Abusir el-Meleq archaeological site in Middle Egypt, which date from the Ptolemaic Kingdom. The W5 subclade has been foun ...
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Human Mitochondrial DNA Haplogroup
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the mitochon ...
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Western Asia
Western Asia, West Asia, or Southwest Asia, is the westernmost subregion of the larger geographical region of Asia, as defined by some academics, UN bodies and other institutions. It is almost entirely a part of the Middle East, and includes Anatolia, the Arabian Peninsula, Iran, Mesopotamia, the Armenian Highlands, the Levant, the island of Cyprus, the Sinai Peninsula, and partly the Caucasus Region (Transcaucasia). The region is considered to be separated from Africa by the Isthmus of Suez in Egypt, and separated from Europe by the waterways of the Turkish Straits and the watershed of the Greater Caucasus. Central Asia lies to its northeast, while South Asia lies to its east. Twelve seas surround the region (clockwise): the Aegean Sea, the Sea of Marmara, the Black Sea, the Caspian Sea, the Persian Gulf, the Gulf of Oman, the Arabian Sea, the Gulf of Aden, the Red Sea, the Gulf of Aqaba, the Gulf of Suez, and the Mediterranean Sea. Western Asia covers an area of , with a p ...
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Abusir
Abusir ( ar, ابو صير  ; Egyptian ''pr wsjr'' cop, ⲃⲟⲩⲥⲓⲣⲓ ' "the House or Temple of Osiris"; grc, Βούσιρις) is the name given to an Egyptian archaeological locality – specifically, an extensive necropolis of the Old Kingdom period, together with later additions – in the vicinity of the modern capital Cairo. The name is also that of a neighbouring village in the Nile Valley, whence the site takes its name. Abusir is located several kilometres north of Saqqara and, like it, served as one of the main elite cemeteries for the ancient Egyptian capital city of Memphis. Several other villages in northern and southern Egypt are named Abusir or Busiri. Abusir is one relatively small segment of the extensive "pyramid field" that extends from north of Giza to below Saqqara. The locality of Abusir took its turn as the focus of the prestigious western burial rites operating out of the then-capital of Memphis during the Old Kingdom 5th Dynasty. As an e ...
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Population Genetics
Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure. Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, laboratory, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and adaptive dynamics, is its emphasis on such genetic phenomena as dominance, epi ...
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Human Mitochondrial Genetics
Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. There are theories, however, that paternal mtDNA transmission in humans can occur under certain circumstances. Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the genetic material of a fertilized egg (zygote) derives from each parent. Eighty percent of mitochondrial DNA codes for mitochondrial RNA, and therefore most mitochondrial DNA mutations lead to functional problems, ...
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Genetic Genealogy
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. As of 2019, about 30 million people had been tested. As the field developed, the aims of practitioners broadened, with many seeking knowledge of their ancestry beyond the recent centuries, for which traditional pedigrees can be constructed. History The investigation of surnames in genetics can be said to go back to George Darwin, a son of Charles Darwin and Charles' first cousin Emma Darwin. In 1875, George Darwin used surnames to estimate the frequency of first-cousin marriages and calculated t ...
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Genealogical DNA Test
A genealogical DNA test is a DNA-based test used in genetic genealogy that looks at specific locations of a person's genome in order to find or verify ancestral genealogical relationships, or (with lower reliability) to estimate the ethnic mixture of an individual. Since different testing companies use different ethnic reference groups and different matching algorithms, ethnicity estimates for an individual vary between tests, sometimes dramatically. Three principal types of genealogical DNA tests are available, with each looking at a different part of the genome and being useful for different types of genealogical research: autosomal (atDNA), mitochondrial (mtDNA), and Y-DNA. Autosomal tests may result in a large number of DNA matches to both males and females who have also tested with the same company. Each match will typically show an estimated degree of relatedness, i.e., a close family match, 1st-2nd cousins, 3rd-4th cousins, etc. The furthest degree of relationship is u ...
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Phylogenetic Tree Of Haplogroups N1a1b And W
In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, protein amino acid sequences, or morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An unrooted tree diagram (a network) makes no assumption about the ancestral line, and does ...
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Sungir
Sungir (, sometimes spelled Sunghir) is an Upper Paleolithic archaeological site in Russia and one of the earliest records of modern ''Homo sapiens'' in Eurasia. It is situated about two hundred kilometres east of Moscow, on the outskirts of Vladimir, near the Klyazma River. It is dated by calibrated carbon analysis to between 32,050 and 28,550 BC. Additional pollen finds suggest the relative warm spell of the "Greenland interstadial (GI) 5" between the 305th and 301st centennia BCE as most probable dates. The settlement area was found to have four burials: the remains of an older man and two adolescent children are particularly well-preserved, and the nature of the rich and extensive burial goods suggests they belonged to the same class. In addition, a skull and two fragments of human femur were also found at the settlement area, and two human skeletons outside the settlement area without cultural remains. History This site was discovered in 1955, in the course of local digging ...
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Starčevo Culture
The Starčevo culture is an archaeological culture of Southeastern Europe, dating to the Neolithic period between ''c.'' 6200 and 4500 BCE. It originates in the spread of the Neolithic package of peoples and technological innovations including farming and ceramics from Anatolia to the area of Sesklo. The Starčevo culture marks its spread to the inland Balkan peninsula as the Cardial ware culture did along the Adriatic coastline. It forms part of the wider Starčevo–Körös–Criş culture which gave rise to the central European Linear Pottery culture c. 700 years after the initial spread of Neolithic farmers towards the northern Balkans. The Starčevo site, the type site, is located on the north bank of the Danube near the village of Starčevo in Serbia (Vojvodina province), opposite Belgrade. Origins The Starčevo culture represents a northern expansion of Early European Farmers, Early Neolithic Farmers who settled from Anatolia to present-day central Greece and expanded n ...
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