Gigantine
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Gigantine
Gigantine is an tetrahydroisoquinoline alkaloid found in ''Carnegiea gigantea'' and other related cacti. Gigantine was first discovered along with macromerine in 1967. It is found in significant quantities in many mescaline-containing cactus species, but it is unclear whether gigantine contributes in any way to their psychoactive A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. Th ... effects.Shulgin AT, Perry WE. The Simple Plant Isoquinolines. Transform Press, 2002. References {{Reflist Norsalsolinol ethers ...
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Carnegiea Gigantea
The saguaro (, ) (''Carnegiea gigantea'') is a tree-like cactus species in the monotypic genus ''Carnegiea'' that can grow to be over tall. It is native to the Sonoran Desert in Arizona, the Mexican state of Sonora, and the Whipple Mountains and Imperial County areas of California. The saguaro blossom is the state wildflower of Arizona. Its scientific name is given in honor of Andrew Carnegie. In 1994, Saguaro National Park, near Tucson, Arizona, was designated to help protect this species and its habitat. Saguaros have a relatively long lifespan, often exceeding 150 years. They may grow their first side arm around 75–100 years of age, but some never grow any arms. Arms are developed to increase the plant's reproductive capacity, as more apices lead to more flowers and fruit. A saguaro can absorb and store considerable amounts of rainwater, visibly expanding in the process, while slowly using the stored water as needed. This characteristic enables the saguaro to ...
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Tetrahydroisoquinoline
Tetrahydroisoquinoline (TIQ or THIQ) is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline by hydrogenation. It is a colorless viscous liquid that is miscible with most organic solvents. The tetrahydroisoquinoline skeleton is encountered in a number of bioactive compounds and drugs. Reactions As a secondary amine, tetrahydroisoquinoline has weakly basic properties and forms salts with strong acids. It can be dehydrogenated to give isoquinoline and hydrogenated to decahydroisoquinoline. Like other secondary amines, tetrahydroisoquinoline can be oxidized to the corresponding nitrone using hydrogen peroxide, catalyzed by selenium dioxide. Toxicology Tetrahydroisoquinoline derivatives may be formed in the body as metabolites of some drugs, and this was once thought to be involved in the development of alcoholism. This theory has now been discredited and is no longer generally accepted by the scientific community, ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ...
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Macromerine
Macromerine is a phenethylamine derivative. It was first identified from the cactus '' Coryphantha macromeris''. It can also be found in ''C. runyonii'', ''C. elephantidens'', and other related members of the family Cactaceae. The plants may have been used by Tarahumara shamans for their entheogen Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoac ...ic effects. Chemistry Macromerine is a phenethylamine derivative with the molecular formula C12H19NO3. Effects At least one study found macromerine to be non-psychoactive, however as a phenethylamine derivative, it may be psychoactive. See also * Phenethylamine cactus * Mescaline References {{Phenethylamines Phenethylamine alkaloids Phenethylamines Phenol ethers Phenylethanolamines ...
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Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sources It occurs naturally in several species of cacti. It is also found in small amounts in certain members of the bean family, Fabaceae, including ''Acacia berlandieri''. However those claims concerning ''Acacia'' species have been challenged and have been unsupported in any additional analysis. History and use Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador. While religious and ceremonial peyote use was widespread in the Aztec empire and northern M ...
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Psychoactive Substance
A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. These substances may be used medically, recreationally or spiritually to a. Purposefully improve one’s perceived performance b. Alter one's consciousness (such as with entheogens for ritual, spiritual or shamanic purposes) or c. For research. Some categories of psychoactive drugs - which are believed, by some, to have therapeutic value - may be prescribed by some physicians and other healthcare practitioners. Examples of medication categories that may contain potentially beneficial psychoactive drugs include, but are not limited to: # Anesthetics # Analgesics # Anticonvulsants # Anti-Parkinson’s medications # Medications used to treat Neuropsychiatric Disorders a. Antidepressants b. Anxiolytics c. Antipsychotics d. Sti ...
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