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Genomic Selection
Genomic Selection (GS) predicts the breeding values of an offspring in a population by associating their traits (i.e. resistance to pests) with their high-density genetic marker scores. GS is a method proposed to address deficiencies of marker-assisted selection (MAS) in breeding programs. However, GS is a form of MAS that differs from it by estimating, at the same time, all genetic markers, haplotypes or marker effects along the entire genome to calculate the values of genomic estimated breeding values (GEBV). The potentiality of GS is to explain the genetic diversity of a breeding program through a high coverage of genome-wide markers and to assess the effects of those markers to predict breeding values. MAS limitations In contrast to MAS and its focus on a few significant markers, GS examines together all markers in a population. Since the initial proposal of GS for application in breeding populations, it has been emerging as a solution to the deficiencies of MAS. The MAS has ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marker-assisted Selection
Marker assisted selection or marker aided selection (MAS) is an indirect selection process where a trait of interest is selected based on a marker ( morphological, biochemical or DNA/ RNA variation) linked to a trait of interest (e.g. productivity, disease resistance, abiotic stress tolerance, and quality), rather than on the trait itself.Ribaut, J.-M. et al., Genetic basis of physiological traits. In Application of Physiology in Wheat Breeding, CIMMYT, Mexico, 2001.Ribaut, J.-M. and Hoisington, D. A., Marker assisted selection: new tools and strategies. Trends Plant Sci., 1998, 3, 236–239.Rosyara, U.R. 2006. REQUIREMENT OF ROBUST MOLECULAR MARKER TECHNOLOGY FOR PLANT BREEDING APPLICATIONS. Journal of Plant Breed. Gr. 1: 67 – 72click to download/ref> This process has been extensively researched and proposed for plant and animal breeding. For example, using MAS to select individuals with disease resistance involves identifying a marker allele that is linked with disease resi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breeding Program
A breeding program is the planned breeding of a group of animals or plants, usually involving at least several individuals and extending over several generations. There are a couple of breeding methods, such as artificial (which is man made) and natural (it occurs on its own). According to the Dutch State Secretary of Economic Affairs the delivery of young animals is important for the natural behavior of the mother, the herd and is desirable from a veterinary perspective. Breeding programs are commonly employed in several fields where humans wish to change the characteristics of their animals' offspring through careful selection of breeding partners: *Dog and cat fanciers may coordinate a breeding program to raise the probability of an animal's litter producing a championship-caliber animal. *Horse breeders try to produce fast racehorses through breeding programs. *Conservationists use breeding programs to try to help the recovery of endangered species by preserving the exis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whole Genome Sequencing
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondrial DNA, mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of DNA sequencing, gene sequencing at Single-nucleotide polymorphism, SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quantitative Trait Locus
A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. This is often an early step in identifying the actual genes that cause the trait variation. Definition A quantitative trait locus (QTL) is a region of DNA which is associated with a particular phenotypic trait, which varies in degree and which can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment. . These QTLs are often found on different chromosomes. The number of QTLs which explain variation in the phenotypic trait indicates the genetic architecture of a trait. It may indicate that plant height is controlled by many genes of small effect, or by a few genes of large effect. Typically, QTLs underlie continuous traits (those traits which vary continuously, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Faculty Opinions Ltd
F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than before, publishing a research article. Initially, F1000 was named after the 1,000 faculty members that performed peer-reviews, but over time F1000 expanded to more than 8,000 members. When F1000 was acquired by Taylor & Francis Group in January 2020, it kept the publishing services. F1000Prime (AKA Faculty Opinions) and F1000 Workspace (AKA Sciwheel) were acquired by different brands. History ''Faculty of 1000'' was founded in 2000 by publishing entrepreneur Vitek Tracz in London. Initially, it was named after the 1,000 experts it had reviewing academic works, but over time F1000 expanded to more than 8,000 members. In 2002, it introduced F1000Prime (later known as Faculty Opinions), which recommended scientific articles selected by its e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Briefings In Functional Genomics
''Briefings in Functional Genomics'' is a bimonthly peer-reviewed scientific journal covering genomics. It was established in 2002 as ''Briefings in Functional Genomics & Proteomics'', obtaining its current title in 2010. It is published by Oxford University Press and the editor-in-chief is Paul Hurd (Queen Mary University of London). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 4.241. References External links * Genetics in the United Kingdom Genomics journals Oxford University Press academic journals English-language journals Publications established in 2002 {{genetics-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cham, Switzerland
Cham is a municipality in the canton of Zug in Switzerland. Location Cham is located on the northern shore of Lake Zug, northwest of the cantonal capital of Zug. Surrounding Cham, Steinhausen is to the east, Hünenberg is to the west, Lake Zug is south, and Maschwanden and Knonau in the Canton of Zürich are to the north. The town has an area of . The train station is located above sea level and the highest point in town is above sea level. The town is located at the mouth of the Lorze river, with two sections (Kirchbühl and Städtli) located on both sides of the river. Cham also includes a number of smaller villages; Enikon, Lindencham, Friesencham, Hagendorn, Rumentikon, Niederwil, Oberwil and Bibersee. Cham has an area, , of . Of this area, 63.3% is used for agricultural purposes, while 13.2% is forested. Of the rest of the land, 21.7% is settled (buildings or roads) and the remainder (1.8%) is non-productive (rivers, glaciers or mountains). History The shores of Lak ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Springer International Publishing AG
Springer Nature or the Springer Nature Group is a German-British academic publishing company created by the May 2015 merger of Springer Science+Business Media and Holtzbrinck Publishing Group's Nature Publishing Group, Palgrave Macmillan, and Macmillan Education. History The company originates from a number of journals and publishing houses, notably Springer-Verlag, which was founded in 1842 by Julius Springer in Berlin (the grandfather of Bernhard Springer who founded Springer Publishing in 1950 in New York), Nature Publishing Group Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in scie ... which has published ''Nature (journal) , Nature'' since 1869, and Macmillan Education, which goes back to Macmillan Publishers founded in 1843. Springer Nature was formed in 2015 by the merger of Natu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complex Traits
Complex traits, also known as quantitative traits, are traits that do not behave according to simple Mendelian inheritance laws. More specifically, their inheritance cannot be explained by the genetic segregation of a single gene. Such traits show a continuous range of variation and are influenced by both environmental and genetic factors. Compared to strictly Mendelian traits, complex traits are far more common, and because they can be hugely polygenic, they are studied using statistical techniques such as QTL mapping rather than classical genetics methods. Examples of complex traits include height, circadian rhythms, enzyme kinetics, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits. History When Mendel’s work on inheritance was rediscovered in 1900, scientists debated whether Mendel’s laws could account for t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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