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Fumigaclavine A
Fumigaclavine A is an antibacterial ergoline alkaloid produced by endophytic '' Aspergillus''. Both 8α and 8β diastereomers (epimers) were named fumigaclavine A in scientific literature. See also * Fumigaclavine B * Fumigaclavine C Fumigaclavine C is an ergoline alkaloid produced by ''Aspergillus fumigatus ''Aspergillus fumigatus'' is a species of fungus in the genus ''Aspergillus'', and is one of the most common ''Aspergillus'' species to cause disease in individuals wit ... * Fumigaclavine A dimethylallyltransferase References Ergolines Acetate esters {{alkaloid-stub ...
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Ergoline
Ergoline is a chemical compound whose structural skeleton is contained in a variety of alkaloids, referred to as ergoline derivatives or ergoline alkaloids. Ergoline alkaloids, one being ergine, were initially characterized in ergot. Some of these are implicated in the condition ergotism, which can take a convulsive form or a gangrenous form. Even so, many ergoline alkaloids have been found to be clinically useful. Annual world production of ergot alkaloids has been estimated at 5,000–8,000 kg of all ergopeptines and 10,000–15,000 kg of lysergic acid, used primarily in the manufacture of semi-synthetic derivatives. Others, such as lysergic acid diethylamide, better known as LSD, a semi-synthetic derivative, and ergine, a natural derivative found in ''Argyreia nervosa'', ''Ipomoea tricolor'' and related species, are known psychedelic substances. Natural occurrence Ergoline alkaloids are found in lower fungi and some species of flowering plants: the Mexican species ...
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Aspergillus
'''' () is a genus consisting of several hundred mold species found in various climates worldwide. ''Aspergillus'' was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli. Viewing the fungi under a microscope, Micheli was reminded of the shape of an ''aspergillum'' (holy water sprinkler), from Latin ''spargere'' (to sprinkle), and named the genus accordingly. Aspergillum is an asexual spore-forming structure common to all ''Aspergillus'' species; around one-third of species are also known to have a sexual stage. While some species of ''Aspergillus'' are known to cause fungal infections, others are of commercial importance. Taxonomy Species ''Aspergillus'' consists of 837 species of fungi. Growth and distribution ''Aspergillus'' is defined as a group of conidial fungi—that is, fungi in an asexual state. Some of them, however, are known to have a teleomorph (sexual state) in the Ascomycota. With DNA evidence, all members of the genus '' ...
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Fumigaclavine B
Fumigaclavine B is an ergoline compound made by certain fungi. Both 8α and 8β diastereomers (epimers) were named fumigaclavine B in scientific literature. See also * Fumigaclavine A * Fumigaclavine C Fumigaclavine C is an ergoline alkaloid produced by ''Aspergillus fumigatus ''Aspergillus fumigatus'' is a species of fungus in the genus ''Aspergillus'', and is one of the most common ''Aspergillus'' species to cause disease in individuals wit ... * Fumigaclavine B O-acetyltransferase References * https://pubchem.ncbi.nlm.nih.gov/compound/46173120#section=Top Ergolines {{alkaloid-stub ...
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Fumigaclavine C
Fumigaclavine C is an ergoline alkaloid produced by ''Aspergillus fumigatus ''Aspergillus fumigatus'' is a species of fungus in the genus ''Aspergillus'', and is one of the most common ''Aspergillus'' species to cause disease in individuals with an immunodeficiency. ''Aspergillus fumigatus'', a saprotroph widespread in ...''. Both 8α and 8β diastereomers (epimers) were named fumigaclavine C in scientific literature. See also * 9-Deacetoxyfumigaclavine C * Fumigaclavine A * Fumigaclavine B * Fumigaclavine A dimethylallyltransferase * Desformylflustrabromine References Ergolines Acetate esters {{alkaloid-stub ...
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Fumigaclavine A Dimethylallyltransferase
Fumigaclavine A dimethylallyltransferase (, ''FgaPT1'') is an enzyme with systematic name ''dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase''. This enzyme catalyses the following chemical reaction : fumigaclavine A + dimethylallyl diphosphate \rightleftharpoons fumigaclavine C + diphosphate Fumigaclavine C is an ergot alkaloid produced by some fungi A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from ... of the '' Trichocomaceae'' family. References External links * {{Portal bar, Biology, border=no EC 2.5.1 ...
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Ergolines
Ergoline is a chemical compound whose structural skeleton is contained in a variety of alkaloids, referred to as ergoline derivatives or ergoline alkaloids. Ergoline alkaloids, one being ergine, were initially characterized in ergot. Some of these are implicated in the condition ergotism, which can take a convulsive form or a gangrenous form. Even so, many ergoline alkaloids have been found to be clinically useful. Annual world production of ergot alkaloids has been estimated at 5,000–8,000 kg of all ergopeptines and 10,000–15,000 kg of lysergic acid, used primarily in the manufacture of semi-synthetic derivatives. Others, such as lysergic acid diethylamide, better known as LSD, a semi-synthetic derivative, and ergine, a natural derivative found in ''Argyreia nervosa'', ''Ipomoea tricolor'' and related species, are known psychedelic substances. Natural occurrence Ergoline alkaloids are found in lower fungi and some species of flowering plants: the Mexican species ...
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