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Friulimicin
Friulimicin B is a lipopeptide antibiotic produced by ''Actinoplanes friuliensis ''Actinoplanes friuliensis'' is a species of bacteria that produces lipopeptide antibiotics with peptidoglycan Peptidoglycan or murein is a unique large macromolecule, a polysaccharide, consisting of sugars and amino acids that forms a mesh-li ...''. It includes the unusual amino acid methylaspartate. References {{reflist Antibiotics Lipopeptides Cyclic peptides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actinoplanes Friuliensis
''Actinoplanes friuliensis'' is a species of bacteria that produces lipopeptide antibiotics with peptidoglycan synthesis-inhibiting activity, called friulimicin Friulimicin B is a lipopeptide antibiotic produced by ''Actinoplanes friuliensis ''Actinoplanes friuliensis'' is a species of bacteria that produces lipopeptide antibiotics with peptidoglycan Peptidoglycan or murein is a unique large macromo ...s. References Further reading * * External links *LPSN Micromonosporaceae [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipopeptide
A lipopeptide is a molecule consisting of a lipid connected to a peptide. They are able to self-assemble into different structures. Many bacteria produced these molecules as a part of their metabolism, especially those of the genus ''Bacillus'', ''Pseudomonas'' and ''Streptomyces''. Certain lipopeptides are used as antibiotics. Other lipopeptides are toll-like receptor agonists. Certain lipopeptides can have strong antifungal and hemolytic activities. It has been demonstrated that their activity is generally linked to interactions with the plasma membrane, and sterol components of the plasma membrane could play a major role in this interaction. It is a general trend that adding a lipid group of a certain length (typically C10–C12) to a lipopeptide will increase its bactericidal activity. Lipopeptides with a higher amount of carbon atoms, for example 14 or 16, in its lipid tail will typically have antibacterial activity as well as anti-fungal activity. Lipopeptide detergents (LPDs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
L-threo-3-methylaspartate
-''threo''-3-Methylaspartate is an unusual amino acid formed by glutamate mutase and can be metabolised by methylaspartate ammonia-lyase. It is found in the structures of the antibiotics friulimicin and vicenistatin and in carbon metabolism of haloarchaea Haloarchaea (halophilic archaea, halophilic archaebacteria, halobacteria) are a class of the Euryarchaeota, found in water saturated or nearly saturated with salt. Halobacteria are now recognized as archaea rather than bacteria and are one of t ... ( Methylaspartate cycle). References {{DEFAULTSORT:Methylaspartate, L-threo-3- Amino acids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipopeptides
A lipopeptide is a molecule consisting of a lipid connected to a peptide. They are able to self-assemble into different structures. Many bacteria produced these molecules as a part of their metabolism, especially those of the genus ''Bacillus'', ''Pseudomonas'' and ''Streptomyces''. Certain lipopeptides are used as antibiotics. Other lipopeptides are toll-like receptor agonists. Certain lipopeptides can have strong antifungal and hemolytic activities. It has been demonstrated that their activity is generally linked to interactions with the plasma membrane, and sterol components of the plasma membrane could play a major role in this interaction. It is a general trend that adding a lipid group of a certain length (typically C10–C12) to a lipopeptide will increase its bactericidal activity. Lipopeptides with a higher amount of carbon atoms, for example 14 or 16, in its lipid tail will typically have antibacterial activity as well as anti-fungal activity. Lipopeptide detergents (LPDs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
