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Fading Puppy Syndrome
Fading puppy syndrome (or fading puppy complex) is when a puppy dies within the first few weeks of life without a clear cause of death or clinical signs, that is to say, they fail to thrive. Death usually occurs within the first five days of life, but can happen up to ten weeks of age. It is responsible for about 50% of deaths of new-born puppies. Around 30% of pedigree puppies die in their first few weeks of life, with only about half of them dying due to identifiable causes. General Like other species of mammals, canine puppies are very vulnerable during their first weeks of life, partly because they have no ability to regulate their own body temperature and their immune systems are not yet fully developed. It is estimated that the mortality rate is around 20-30% of "live-born pedigree puppies" in the first three weeks of life. Signs of the syndrome can include weakness, low body temperature, and 'paddling'. Contributing factors Some of the more common possible causes of fa ...
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Puppy
A puppy is a juvenile dog. Some puppies can weigh , while larger ones can weigh up to . All healthy puppies grow quickly after birth. A puppy's coat color may change as the puppy grows older, as is commonly seen in breeds such as the Yorkshire Terrier. ''Puppy'' refers specifically to young dogs, while ''pup'' may be used for other animals such as wolves, seals, giraffes, guinea pigs, rats or sharks. Development Puppies are born after an average of 63 days of gestation, puppies emerge in an amnion that is bitten off and eaten by the mother dog. Puppies begin to nurse almost immediately. If the litter exceeds six puppies, particularly if one or more are obvious runts, human intervention in hand-feeding the stronger puppies is necessary to ensure that the runts get proper nourishment and attention from the mother. As they reach one month of age, puppies are gradually weaned and begin to eat solid food. The mother may regurgitate partially digested food for the puppies or migh ...
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Canine Parvovirus
Canine parvovirus (also referred to as CPV, CPV2, or parvo) is a contagious virus mainly affecting dogs. CPV is highly contagious and is spread from dog to dog by direct or indirect contact with their feces. Vaccines can prevent this infection, but mortality can reach 91% in untreated cases. Treatment often involves veterinary hospitalization. Canine parvovirus often infects other mammals including foxes, wolves, cats, and skunks. Felines (cats) are also susceptible to panleukopenia, a different strain of parvovirus. Signs Dogs that develop the disease show signs of the illness within three to ten days. The signs may include lethargy, vomiting, fever, and diarrhea (usually bloody). Generally, the first sign of CPV is lethargy. Secondary signs are loss of weight and appetite or diarrhea followed by vomiting. Diarrhea and vomiting result in dehydration that upsets the electrolyte balance and this may affect the dog critically. Secondary infections occur as a result of the weaken ...
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Neonatal Isoerythrolysis
Neonatal isoerythrolysis (NI), also known as hemolytic icterus or hemolytic anemia, is a disease most commonly seen in kittens and foals, but has also been reported in puppies. It occurs when the mother has antibodies against the blood type of the newborn. Neonatal isoerythrolysis in kittens In cats, the antibodies are already present in the queen's blood before parturition. The blood group antigens are similar in structure to the antigen of a common bacteria in the gut of cats leading to antibody formation. Kittens obtain the majority of their immune response from the colostrum, and are not born with a strong immune response. When they absorb the mother's antibodies against their blood type it causes lysis of the red blood cells leading to anemia. Symptoms include lethargy, weakness, depression, pale mucus membranes, fever, and blood in the urine. Hypoxia may lead to forebrain disease, increased heart rate and respiratory rate, and liver or kidney disease. Animals suffering from ...
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Sepsis
Sepsis, formerly known as septicemia (septicaemia in British English) or blood poisoning, is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage is followed by suppression of the immune system. Common signs and symptoms include fever, tachycardia, increased heart rate, hyperventilation, increased breathing rate, and mental confusion, confusion. There may also be symptoms related to a specific infection, such as a cough with pneumonia, or dysuria, painful urination with a pyelonephritis, kidney infection. The very young, old, and people with a immunodeficiency, weakened immune system may have no symptoms of a specific infection, and the hypothermia, body temperature may be low or normal instead of having a fever. Severe sepsis causes organ dysfunction, poor organ function or blood flow. The presence of Hypotension, low blood pressure, high blood Lactic acid, lactate, or Oliguria, low urine o ...
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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ...
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Canine Adenovirus
Infectious canine hepatitis (ICH) is an acute liver infection in dogs caused by ''Canine mastadenovirus A'', formerly called ''Canine adenovirus 1'' (CAV-1). CAV-1 also causes disease in wolves, coyotes, and bears, and encephalitis in foxes. The virus is spread in the feces, urine, blood, saliva, and nasal discharge of infected dogs. It is contracted through the mouth or nose, where it replicates in the tonsils. The virus then infects the liver and kidneys. The incubation period is 4 to 9 days. Symptoms include fever, depression, loss of appetite, coughing, and a tender abdomen. Corneal edema and signs of liver disease, such as jaundice, vomiting, and hepatic encephalopathy, may also occur. Severe cases will develop bleeding disorders, which can cause hematomas to form in the mouth. Death can occur secondary to this or the liver disease. However, most dogs recover after a brief illness, although chronic corneal edema and kidney lesions may persist. Diagnosis is made by re ...
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Metritis
Metritis is inflammation of the wall of the uterus, whereas endometritis is inflammation of the functional lining of the uterus, called the endometrium. The term pelvic inflammatory disease (PID) is often used for metritis. Definitions Postpartum metritis, also known as puerperal sepsis, occurs within 21 days and is most common within 10 days of delivery. Metritis is characterized by an enlarged uterus and a watery red-brown fluid to viscous off-white purulent uterine discharge, which often has a bad smell. The severity of disease is categorized by the signs of health: *Grade 1 metritis: An abnormally enlarged uterus and a purulent uterine discharge without any systemic signs of ill health. *Grade 2 metritis: Animals with additional signs of systemic illness such as decreased milk yield, dullness, and fever >39.5 °C. *Grade 3 metritis: Animals with signs of toxemia such as inappetence, cold extremities, depression, and/or collapse. Clinical endometritis is defined in c ...
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Mastitis
Mastitis is inflammation of the breast or udder, usually associated with breastfeeding. Symptoms typically include local pain and redness. There is often an associated fever and general soreness. Onset is typically fairly rapid and usually occurs within the first few months of delivery. Complications can include abscess formation. Risk factors include poor latch, cracked nipples, use of a breast pump, and weaning. The bacteria most commonly involved are '' Staphylococcus'' and '' Streptococci''. Diagnosis is typically based on symptoms. Ultrasound may be useful for detecting a potential abscess. Prevention is by proper breastfeeding techniques. When infection is present, antibiotics such as cephalexin may be recommended. Breastfeeding should typically be continued, as emptying the breast is important for healing. Tentative evidence supports benefits from probiotics. About 10% of breastfeeding women are affected. Types When it occurs in breastfeeding mothers, it is known as puer ...
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In Practice
''De facto'' ( ; , "in fact") describes practices that exist in reality, whether or not they are officially recognized by laws or other formal norms. It is commonly used to refer to what happens in practice, in contrast with ''de jure'' ("by law"), which refers to things that happen according to official law, regardless of whether the practice exists in reality. History In jurisprudence, it mainly means "practiced, but not necessarily defined by law" or "practiced or is valid, but not officially established". Basically, this expression is opposed to the concept of "de jure" (which means "as defined by law") when it comes to law, management or technology (such as standards) in the case of creation, development or application of "without" or "against" instructions, but in accordance with "with practice". When legal situations are discussed, "de jure" means "expressed by law", while "de facto" means action or what is practiced. Similar expressions: "essentially", "unofficial", "in ...
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Canine Herpesvirus
''Canid alphaherpesvirus 1'' (CaHV-1), formerly ''Canine herpesvirus'' (CHV), is a virus of the family ''Herpesviridae'' which most importantly causes a fatal hemorrhagic disease in puppies (and in wild ''Canidae'') less than two to three weeks old. It is known to exist in the United States, Canada, Australia, Japan, England and Germany. CHV was first recognized in the mid-1960s from a fatal disease in puppies. CHV in puppies The incubation period of CHV is six to ten days. CHV is transmitted to puppies in the birth canal and by contact with infected oral and nasal secretions from the mother or other infected dogs, but it is not spread through the air. The virus replicates in the surface cells of the nasal mucosa, tonsils, and pharynx. Low body temperature allows the virus to spread and infect the rest of the body. Symptoms include crying, weakness, depression, discharge from the nose, soft, yellow feces, and a loss of the sucking reflex. CHV also causes a necrotizing vascu ...
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Fail To Thrive
Failure to thrive (FTT), also known as weight faltering or faltering growth, indicates insufficient weight gain or absence of appropriate physical growth in children. FTT is usually defined in terms of weight, and can be evaluated either by a low weight for the child's age, or by a low rate of increase in the weight. The term "failure to thrive" has been used in different ways, as there is no objective standard or universally accepted definition for when to diagnose FTT. One definition describes FTT as a fall in one or more weight centile spaces on a World Health Organization (WHO) growth chart depending on birth weight or when weight is below the 2nd percentile of weight for age irrespective of birth weight. Another definition of FTT is a weight for age that is consistently below the 5th percentile or weight for age that falls by at least two major percentile lines on a growth chart. While weight loss after birth is normal and most babies return to their birth weight by three wee ...
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Toxocara Canis
''Toxocara canis'' (also known as dog roundworm) is a worldwide-distributed helminth parasite of dogs and other canids. The name is derived from the Greek word "," meaning bow or quiver, and the Latin word "caro," meaning flesh.Bassert , J., & Thomas, J. (2014). McCurnin's Clinical Textbook for Veterinary Technicians. (8th ed.). St. Louis , MO: Elsevier They live in the small intestine of the definitive host. In adult dogs, the infection is usually asymptomatic but may be characterized by diarrhea. By contrast, massive infection with ''Toxocara canis'' can be fatal in puppies, causing diarrhea, vomiting, an enlarged abdomen, flatulence, and poor growth rate. As paratenic hosts, a number of vertebrates, including humans, and some invertebrates can become infected. Humans are infected, like other paratenic hosts, by ingestion of embryonated ''T. canis'' eggs. The disease (toxocariasis) caused by migrating ''T. canis'' larvae results in two syndromes: visceral larva migrans and ocu ...
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