Essential Drugs
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Essential Drugs
Essential medicines, as defined by the World Health Organization (WHO), are the medicines that "satisfy the priority health care needs of the population". These are the medications to which people should have access at all times in sufficient amounts. The prices should be at generally affordable levels. Since 1977, the WHO has published a model list of essential medicines, with the current (2019) list for adult patients containing over 400 medicines. Since 2007, a separate list of medicines intended for child patients has been published. Both the WHO adult and children's lists contain a notation indicating that a particular medication is "complementary", thus essentially there are two lists, the "core list" and the "complementary list". The ''core list'' presents a list of minimum medicine needs for a basic health care system, listing the most efficacious, safe and cost-effective medicines for priority conditions. Priority conditions are selected on the basis of current and es ...
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V1 40 Years Model List Of Essential Medicines
V1, V01 or V-1 can refer to version one (for anything) (e.g., see version control) V1, V01 or V-1 may also refer to: In aircraft * V-1 flying bomb, a World War II German weapon * V1 speed, the maximum speed at which an aircraft pilot may abort a takeoff without causing a runway overrun * Vultee V-1, an American single-engine airliner of the 1930s * Fokker V.1, a German parasol monoplane experimental fighter prototype, built in 1916 * The first prototype/experimental ''(Versuchs)'' airframe of nearly any German WW II-era military aircraft Vessels * V1-class destroyer, a German World War I destroyer class * USS V-1, 1924–1931 designation of the USS ''Barracuda'' (SS-163), first of the US "V-boat" series of submarines * V1, a rudderless single-paddler outrigger canoe In medicine * V1, the primary visual cortex * V1, the ophthalmic nerve, first division of the trigeminal nerve * V1, one of six precordial leads in electrocardiography In astronomy * V1, or ''Hubble variable n ...
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Pharmaceutical Formulation
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word ''formulation'' is often used in a way that includes dosage form. Stages and timeline Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have to be carried out to ensure that the encapsulated drug is compatible with these other substances in a way that does not cause harm, whether direct or indirect. Preformulation involves the characterization of a drug's physical, chemical, and mechanical properties in order to choose what other ingredients (excipients) should be used in the pre ...
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List Of World Health Organization Essential Medicines
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. The list is frequently used by countries to help develop their own local lists of essential medicines. , more than 155 countries have created national lists of essential medicines based on the World Health Organization's model list. This includes both developed and developing countries. The list is divided into core items and complementary items. The core items are deemed to be the most cost-effective options for key health problems and are usable with little additional health care resources. The complementary items either require additional infrastructure such as specially trained health care providers or diagnostic equipment or have a lower cost–benefit ratio. About 25% of items are in the complementary list. Some medicat ...
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Department Of Essential Drugs And Medicines
The mission of the Department of Essential Drugs and Medicines of the World Health Organization is "to help save lives and improve health by closing the huge gap between the potential that essential drugs have to offer and the reality that for millions of people – particularly the poor and disadvantaged – medicines are unavailable, unaffordable, unsafe or improperly used." The EDM provides "global guidance on essential drugs and medicines, and working with countries – at their request – to implement national drug policies to ensure equity of access to essential drugs, drug quality and safety, and rational use of drugs." See also * Campaign for Access to Essential Medicines *Essential medicines *WHO Model List of Essential Medicines The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a hea ...
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Universities Allied For Essential Medicines
Universities Allied for Essential Medicines (UAEM) is a student-led organization working to improve access to and affordability of medicines around the world, and to increase research and development of drugs for neglected tropical diseases. Supported by an active board of directors and guided by an advisory board that includes Partners in Health co-founder Paul Farmer and Nobel Laureate Sir John Sulston, UAEM has mobilized hundreds of students on more than 100 campuses in more than 20 countries. These student advocates have convinced universities worldwide to adopt equitable global access licensing policies for licensing their medical research, in order to make life-saving health innovations affordable and accessible in low and middle income countries. UAEM has published two student-led research projects—the University Report Card, which ranks universities on their contributions to global health and has received coverage in ''The New York Times'' and others; and Re:Route, a map ...
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Campaign For Access To Essential Medicines
The Campaign for Access to Essential Medicines is an international campaign started by Médecins Sans Frontières (MSF) to increase the availability of essential medicines in developing countries. MSF often has difficulties treating patients because the medicines required are too expensive or are no longer produced. Sometimes, the only drugs available are highly toxic or ineffective, and they often have to resort to inadequate testing methods to diagnose patients. The lack of research into diseases that affect most of the world’s poor population is known as the 10-90 gap and it occurs because pharmaceutical companies rarely make a profit when developing drugs for these diseases. Although some countries have created legislation to encourage development of essential but commercially ignored medicines, which are called orphan drugs in the United States, MSF started this campaign in November 1999 to bring more awareness to the issue, using its prize money from its 1999 Nobel Peace ...
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Sustainable Development Goals
The Sustainable Development Goals (SDGs) or Global Goals are a collection of 17 interlinked objectives designed to serve as a "shared blueprint for peace and prosperity for people and the planet, now and into the future".United Nations (2017) Resolution adopted by the General Assembly on 6 July 2017, :File:A RES 71 313 E.pdf, Work of the Statistical Commission pertaining to the 2030 Agenda for Sustainable DevelopmentA/RES/71/313) The goals are: Sustainable Development Goal 1, No poverty, Sustainable Development Goal 2, zero hunger, Sustainable Development Goal 3, good health and well-being, Sustainable Development Goal 4, quality education, Sustainable Development Goal 5, gender equality, Sustainable Development Goal 6, clean water and sanitation, Sustainable Development Goal 7, affordable and clean energy, Sustainable Development Goal 8, decent work and economic growth, Sustainable Development Goal 9, industry, innovation and infrastructure, Sustainable Development Goal 10, Redu ...
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Antidote
An antidote is a substance that can counteract a form of poisoning. The term ultimately derives from the Greek term φάρμακον ἀντίδοτον ''(pharmakon) antidoton'', "(medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents. The antidotes for some particular toxins are manufactured by injecting the toxin into an animal in small doses and extracting the resulting antibodies from the host animals' blood. This results in an antivenom that can be used to counteract venom produced by certain species of snakes, spiders, and other venomous animals. Some animal venoms, especially those produced by arthropods (such as certain spiders, scorpions, and bees) are only potentially lethal when they provoke allergic reactions and induce anaphylactic shock; as such, there is no "antidote" for these venoms; however anaphylactic shock can be treated (e.g. with epinephrine). Some other toxins have no known antidote. For example, the pois ...
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Antimigraine
Antimigraine drugs are medications intended to reduce the effects or intensity of migraine headache. They include drugs for the treatment of acute migraine symptoms as well as drugs for the prevention of migraine attacks. Treatment of acute symptoms Examples of specific antimigraine drug classes include triptans (first line option), ergot alkaloids, ditans and gepants. Migraines can also be treated with unspecific analgesics such as nonsteroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ... (NSAIDs) or acetaminophen. Opioids are not recommended for treatment of migraines. Triptans The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan. Due to their safety, efficacy and selectiv ...
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Cost Effectiveness
Cost-effectiveness analysis (CEA) is a form of economic analysis that compares the relative costs and outcomes (effects) of different courses of action. Cost-effectiveness analysis is distinct from cost–benefit analysis, which assigns a monetary value to the measure of effect. Cost-effectiveness analysis is often used in the field of health services, where it may be inappropriate to monetize health effect. Typically the CEA is expressed in terms of a ratio where the denominator is a gain in health from a measure (years of life, premature births averted, sight-years gained) and the numerator is the cost associated with the health gain. The most commonly used outcome measure is quality-adjusted life years (QALY). Cost–utility analysis is similar to cost-effectiveness analysis. Cost-effectiveness analyses are often visualized on a plane consisting of four quadrants, the cost represented on one axis and the effectiveness on the other axis. Cost-effectiveness analysis focuses on m ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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