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Extrapyramidal Effect
In anatomy, the extrapyramidal system is a part of the motor system network causing involuntary actions. The system is called ''extrapyramidal'' to distinguish it from the tracts of the motor cortex that reach their targets by traveling through the pyramids of the medulla. The pyramidal tracts (corticospinal tract and corticobulbar tracts) may directly innervate motor neurons of the spinal cord or brainstem ( anterior (ventral) horn cells or certain cranial nerve nuclei), whereas the extrapyramidal system centers on the modulation and regulation (indirect control) of anterior (ventral) horn cells. Extrapyramidal tracts are chiefly found in the reticular formation of the pons and medulla, and target lower motor neurons in the spinal cord that are involved in reflexes, locomotion, complex movements, and postural control. These tracts are in turn modulated by various parts of the central nervous system, including the nigrostriatal pathway, the basal ganglia, the cerebellum, the ves ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anatomy
Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function (biology), function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic research, basic sciences that are applied in medicine. The discipline of anatomy is divided into macroscopic scale, macroscopic and microscopic scale, microscopic. Gross anatomy, Macroscopic anatomy, or gross anatomy, is the examination of an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vestibular Nuclei
The vestibular nuclei (VN) are the cranial nuclei for the vestibular nerve located in the brainstem. In Terminologia Anatomica they are grouped in both the pons and the medulla in the brainstem. Structure Path The fibers of the vestibular nerve enter the medulla oblongata on the medial side of those of the cochlear, and pass between the inferior peduncle and the spinal tract of the trigeminal nerve. They then divide into ascending and descending fibers. The latter end by arborizing around the cells of the medial nucleus, which is situated in the area acustica of the rhomboid fossa. The ascending fibers either end in the same manner or in the lateral nucleus, which is situated lateral to the area acustica and farther from the ventricular floor. Some of the axons of the cells of the lateral nucleus, and possibly also of the medial nucleus, are continued upward through the inferior peduncle to the roof nuclei of the opposite side of the cerebellum, to which also other fibers of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts. It is a structure composed of nervous tissue positioned along the rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain (precursor structures exist in onychophorans, gastropods and lancelets). The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal cord are both enclosed in the meninges. The meninges provide a barrier to chemicals dissolv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vestibulospinal Tract
The vestibulospinal tract is a neural tract in the central nervous system. Specifically, it is a component of the extrapyramidal system and is classified as a component of the medial pathway. Like other descending motor pathways, the vestibulospinal fibers of the tract relay information from nuclei to motor neurons. The vestibular nuclei receive information through the vestibulocochlear nerve about changes in the orientation of the head. The nuclei relay motor commands through the vestibulospinal tract. The function of these motor commands is to alter muscle tone, extend, and change the position of the limbs and head with the goal of supporting posture and maintaining balance of the body and head. Classification The vestibulospinal tract is part of the "extrapyramidal system" of the central nervous system. In human anatomy, the extrapyramidal system is a neural network located in the brain that is part of the motor system involved in the coordination of movement. The system i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tectospinal Tract
In humans, the tectospinal tract (or colliculospinal tract) is a nerve tract that coordinates head and eye movements. This tract is part of the extrapyramidal system and connects the midbrain tectum, and cervical regions of the spinal cord. It is responsible for motor impulses that arise from one side of the midbrain to muscles on the opposite side of the body (contralateral). The function of the tectospinal tract is to mediate reflex postural movements of the head in response to visual and auditory stimuli. The portion of the midbrain from where this tract originates is the superior colliculus, which receives afferents from the visual nuclei (primarily the oculomotor nuclei complex), then projects to the contralateral (decussating dorsal to the mesencephalic duct) and ipsilateral portion of the first cervical neuromeres of the spinal cord, the oculomotor and trochlear nuclei in the midbrain and the abducens nucleus in the caudal portion of the pons. The tract descends to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reticulospinal Tract
The reticular formation is a set of interconnected nuclei that are located throughout the brainstem. It is not anatomically well defined, because it includes neurons located in different parts of the brain. The neurons of the reticular formation make up a complex set of networks in the core of the brainstem that extend from the upper part of the midbrain to the lower part of the medulla oblongata. The reticular formation includes ascending pathways to the cortex in the ascending reticular activating system (ARAS) and descending pathways to the spinal cord via the reticulospinal tracts. Neurons of the reticular formation, particularly those of the ascending reticular activating system, play a crucial role in maintaining behavioral arousal and consciousness. The overall functions of the reticular formation are modulatory and premotor, involving somatic motor control, cardiovascular control, pain modulation, sleep and consciousness, and habituation. The modulatory functions are prim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rabbit Syndrome
Rabbit syndrome is a rare form of extrapyramidal side effect of antipsychotic drugs in which perioral tremors occur at a rate of approximately 5 Hz. Rabbit syndrome is characterized by involuntary, fine, rhythmic motions of the mouth along a vertical plane, without involvement of the tongue, and resembling the chewing movements of a rabbit. It is usually seen after years of pharmacotherapy, and is more prominent with high potency drugs like haloperidol, fluphenazine, and pimozide. There is also a low incidence with thioridazine, clozapine, olanzapine, aripiprazole, and low doses of risperidone. Rabbit syndrome can be treated with anticholinergic Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system. These agents inhibit the parasympathetic nervous sys ... drugs. It generally disappears within a few days of treatment but may re-emerge aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extrapyramidal Symptoms
Extrapyramidal symptoms (EPS) are symptoms that are archetypically associated with the extrapyramidal system of the brain's cerebral cortex. When such symptoms are caused by medications or other drugs, they are also known as extrapyramidal side effects (EPSE). The symptoms can be acute (short-term) or chronic (long-term). They include movement dysfunction such as dystonia (continuous spasms and muscle contractions), akathisia (may manifest as motor restlessness), parkinsonism characteristic symptoms such as rigidity, bradykinesia (slowness of movement), tremor, and tardive dyskinesia (irregular, jerky movements). Extrapyramidal symptoms are a reason why subjects drop out of clinical trials of antipsychotics; of the 213 (14.6%) subjects that dropped out of one of the largest clinical trials of antipsychotics (the CATIE trial (Clinical Antipsychotic Trials for Intervention Effectiveness), which included 1460 randomized subjects), 58 (27.2%) of those discontinuations were due to E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Regions In The Human Brain
The human brain anatomical regions are ordered following standard neuroanatomy hierarchies. Functional, connective, and developmental regions are listed in parentheses where appropriate. Hindbrain (rhombencephalon) Myelencephalon * Medulla oblongata **Medullary pyramids **Arcuate nucleus **Olivary body ***Inferior olivary nucleus **Rostral ventrolateral medulla **Caudal ventrolateral medulla **Solitary nucleus (Nucleus of the solitary tract) **Respiratory center- Respiratory groups ***Dorsal respiratory group ***Ventral respiratory group or Apneustic centre ****Pre-Bötzinger complex ****Botzinger complex ****Retrotrapezoid nucleus ****Nucleus retrofacialis ****Nucleus retroambiguus ****Nucleus para-ambiguus **Paramedian reticular nucleus **Gigantocellular reticular nucleus **Parafacial zone **Cuneate nucleus ** Gracile nucleus ** Perihypoglossal nuclei *** Intercalated nucleus *** Prepositus nucleus *** Sublingual nucleus **Area postrema **Medullary cranial nerve nucl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tectospinal Tract
In humans, the tectospinal tract (or colliculospinal tract) is a nerve tract that coordinates head and eye movements. This tract is part of the extrapyramidal system and connects the midbrain tectum, and cervical regions of the spinal cord. It is responsible for motor impulses that arise from one side of the midbrain to muscles on the opposite side of the body (contralateral). The function of the tectospinal tract is to mediate reflex postural movements of the head in response to visual and auditory stimuli. The portion of the midbrain from where this tract originates is the superior colliculus, which receives afferents from the visual nuclei (primarily the oculomotor nuclei complex), then projects to the contralateral (decussating dorsal to the mesencephalic duct) and ipsilateral portion of the first cervical neuromeres of the spinal cord, the oculomotor and trochlear nuclei in the midbrain and the abducens nucleus in the caudal portion of the pons. The tract descends to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lateral Vestibulospinal Tract
The lateral vestibulospinal tract is one of the descending spinal tracts of the ventromedial funiculus. The lateral part of the vestibulospinal tract is the major portion and is composed of fibers originating in the lateral, superior, and inferior vestibular nuclei (primarily the lateral). It projects ipsilaterally down to the lumbar region of the spinal cord. There it helps to maintain an upright and balanced posture by stimulating extensor motor neurons in the legs. It also innervates muscles of the trunk, thus additionally aiding in body posture. The lateral vestibular nuclei receive input from cerebellum, particularly the vestibulocerebellum, or the flocculi and nodulus. The cerebellum aids in coordinating postural adjustments. See also *Decerebrate posturing Abnormal posturing is an involuntary flexion or extension of the arms and legs, indicating severe brain injury. It occurs when one set of muscles becomes incapacitated while the opposing set is not, and an ex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reticulospinal Tract
The reticular formation is a set of interconnected nuclei that are located throughout the brainstem. It is not anatomically well defined, because it includes neurons located in different parts of the brain. The neurons of the reticular formation make up a complex set of networks in the core of the brainstem that extend from the upper part of the midbrain to the lower part of the medulla oblongata. The reticular formation includes ascending pathways to the cortex in the ascending reticular activating system (ARAS) and descending pathways to the spinal cord via the reticulospinal tracts. Neurons of the reticular formation, particularly those of the ascending reticular activating system, play a crucial role in maintaining behavioral arousal and consciousness. The overall functions of the reticular formation are modulatory and premotor, involving somatic motor control, cardiovascular control, pain modulation, sleep and consciousness, and habituation. The modulatory functions are prim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
